Capmul mcm

Amisulpride was gifted by Dr. Reddy's (Hyderabad, India). Labrasol, Transcutol P, lauroglycol 90, capmul MCM were received as gift samples from Gattefosse Company (Mumbai, India). Polyethylene glycol 400 (PEG 400), Polysorbate 80, Oleic acid, coconut oil, Tween 20, Propylene glycol, potassium chloride, Oleic acid, Arachis oil, sodium hydroxide, potassium dihydrogen orthophosphate, potassium chloride were purchased from SD fine chem Ltd (Mumbai, India) are of analytical grade. Methanol and Acetonitrile were purchased from Merck Limited (Mumbai, India). All other chemicals were analytical grade and purchased commercially. Double distilled water was used throughout the study. Solubility 2 ml of each of the selected vehicle was taken in glass vial to which excess of Amisulpride was added. They were mixed using a cyclomixer to facilitate uniform dispersion. Then the mixtures were agitated in a shaker at room temperature. Samples were collected at 48 hrs intervals, centrifuged at 400 rpm for 10 min and filtrated through 0.45 µm membrane filter. The concentration of drug was quantified by U.V. visible spectrophotometer. 18, 19

Raspberry ketone was gift sample from the Kshipra Biotech, Indore, India. Sefsol 218 ® was provided as gift sample from Nikko Chemicals (Tokyo, Japan). The oil vitamin E was purchased from Merck, Mumbai, India. Olive oil and almond oil were purchased from Falcon, Bengaluru (India). Linseed oil was purchased from Sigma-Aldrich, Mumbai, India. Solutol HS 15 was provided as gift samples from Signet Chemicals Corporation Pvt. Ltd, Mumbai, India. Tween 20, tween 60, tween 80 and polyethylene glycol 400 were gifted samples from SD Fine Chemicals, New Delhi, India. Propylene glycol was procured from Thomas Baker Chemicals, Mumbai, India.Capmul MCM, lauroglycol 90 and transcutol P were obtained as gift from Gattefosse (Saint Priest, Cedex, France). HPLC-grade acetonitrile was purchased from Merck, Mumbai, India.