Protocatechuic acid

Manufactured by Tokyo Chemical Industry

Sourced in Japan

Protocatechuic acid is a organic compound that can be used as a laboratory reagent. It is a dihydroxybenzoic acid with the chemical formula C6H6O3.

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Lab products found in correlation

Quercetin, by Merck Group (2 mentions) Gallic acid, by Fujifilm (1 mentions) Epicatechin, by Fujifilm (1 mentions) Apigenin, by Tokyo Chemical Industry (1 mentions) Kaempferol, by Tokyo Chemical Industry (1 mentions) Methanol, by Fujifilm (1 mentions) Luteolin, by Merck Group (1 mentions) 4 hydroxybenzoic acid, by Fujifilm (1 mentions) N hexane, by Fujifilm (1 mentions) Silymarin, by Merck Group (1 mentions) Taxifolin hydrate, by Merck Group (1 mentions) Tnf α, by Thermo Fisher Scientific (1 mentions) Il 1β, by Thermo Fisher Scientific (1 mentions) Interleukin 6 (il 6), by Thermo Fisher Scientific (1 mentions) Glutathione peroxidase gpx, by Randox (1 mentions)

2 protocols using protocatechuic acid

Solvent Extraction of Phytochemicals

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The solvents, n-hexane, dichloromethane (DCM), ethyl acetate (EtOAc), acetone, and methanol (MeOH), were purchased from Wako Pure Chemical Industries (Osaka, Japan). The standard compounds, epicatechin, gallic acid, and 4-hydroxybenzoic acid, were purchased from Wako Pure Chemical Industries (Osaka, Japan). Quercetin and luteolin were purchased from Sigma-Aldrich (St. Louis, MO, USA). Apigenin, protocatechuic acid, and kaempferol were purchased from Tokyo Chemical Industry (Tokyo, Japan).

Mittraphab Y., Amen Y., Nagata M., Matsumoto M., Wang D, & Shimizu K. (2022). Anti-Phototoxicity Effect of Phenolic Compounds from Acetone Extract of Entada phaseoloides Leaves via Activation of COX-2 and iNOS in Human Epidermal Keratinocytes. Molecules, 27(2), 440.

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Hepatoprotective Effects of Antioxidants

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Silymarin, taxifolin hydrate (≥90%), and quercetin (≥98%) were purchased from Sigma–Aldrich Chemical Co. (USA). Protocatechuic acid (≥98%) was purchased from Tokyo Chemical Industry Co. Ltd. (Japan). CCl₄ was purchased from Merck Co. (Germany) and was dissolved in olive oil to form a 0.175% (v/v) solution. Silymarin was suspended in 1% carboxymethylcellulose (CMC). All other reagents used were of analytical grades. Serum aspartate aminotransferase (AST), serum alanine aminotransferase (ALT), alkaline phosphatase (ALP), superoxide dismutase (SOD), glutathione peroxidase (GPx), and glutathione reductase (GRd) assay kits were purchased from Randox Laboratory Ltd., and nitric oxide (NO) and malondialdehyde (MDA) assays were obtained from Cayman Chemical Co. (Ann Arbor, MI, USA). TNF-α, IL-1β, and IL-6 were obtained from eBioscience Inc. (San Diego, CA, USA).

Chiu Y.J., Chou S.C., Chiu C.S., Kao C.P., Wu K.C., Chen C.J., Tsai J.C, & Peng W.H. (2017). Hepatoprotective effect of the ethanol extract of Polygonum orientale on carbon tetrachloride-induced acute liver injury in mice. Journal of Food and Drug Analysis, 26(1), 369-379.

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