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Syngo vvi

Manufactured by Siemens
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Syngo VVI is a software module developed by Siemens for use with their medical imaging equipment. It is designed to provide image visualization and analysis capabilities for vascular applications. The core function of Syngo VVI is to enable the display and assessment of vascular structures based on medical imaging data, such as angiograms or CT scans.

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Lab products found in correlation

Acuson sc2000, by Siemens (1 mentions)

5 protocols using syngo vvi

1

Echocardiographic Assessment of LV-GLS

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LV‐GLS measurements were obtained from baseline transthoracic echocardiograms from gray‐scale images of apical 2‐, 3‐, and 4‐chamber views (A.A., N.I.). The frame rate was at least 30 frames/s. LV‐GLS was analyzed offline using velocity vector imaging (Syngo VVI; Siemens), as described previously.12 After manual definition of the LV endocardial border, the endocardium was automatically tracked throughout the cardiac cycle. LV‐GLS was obtained by averaging all segmental strain values and later by averaging all 3 apical views. No patient was in atrial fibrillation at the time of analysis. Peak global strain was defined as peak negative value on the strain curve during the entire cardiac cycle. All measurements were made by investigators blinded to clinical and demographic information. As reported, LV‐GLS values are negative; a lower absolute number represented a worse value than a higher number. Our group has previously provided data on reproducibility of LV‐GLS measurements using the same software.12, 15
Alashi A., Isaza N., Faulx J., Popovic Z.B., Menon V., Ellis S.G., Faulx M., Kapadia S.R., Griffin B.P, & Desai M.Y. (2020). Characteristics and Outcomes of Patients With Takotsubo Syndrome: Incremental Prognostic Value of Baseline Left Ventricular Systolic Function. Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 9(16), e016537.
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2

Echocardiographic Assessment of Subclinical Systolic and Diastolic Function

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A transthoracic 2-dimensional and Doppler echocardiographic study was performed among using standard equipment (ACUSON SC2000, Siemens Healthcare USA, Mountain View, California and GE E95 ultrasound device, GE Healthcare, Chicago, Illinois, United States) and transducer (4V1c, 1.25 to 4.5 MHz; 4Z1c, 1.5 to 3.5 MHz) in accordance with the American Society of Echocardiography guidelines. Subclinical LV systolic function was assessed with GLS computed using speckle tracking (Syngo VVI; Siemens Healthcare USA) [17 (link)]. Diastolic function was assessed from transmitral flow (peak early [E] and late diastolic velocity E/A ratio), mitral annular early diastolic velocities (e′) and E/e′ ratio, left atrial volume index (LAVi) indexed to body surface area, and tricuspid regurgitation velocity [18 ].
SBHF was defined by the presence of one or more of: (i) diastolic dysfunction (DD) (E/e′ > 15 or E/e′ > 10 with left atrium enlargement (LAE) or impaired relaxation with LAE); (ii) reduced GLS (≤ 18%); or (iii) left ventricular hypertrophy (LVH, LV mass index > 95 g/m2 in women and > 115 g/m2 in men).
Soh C.H., de Sá A.G., Potter E., Halabi A., Ascher D.B, & Marwick T.H. (2024). Use of the energy waveform electrocardiogram to detect subclinical left ventricular dysfunction in patients with type 2 diabetes mellitus. Cardiovascular Diabetology, 23, 91.
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3

Strain Imaging for Cardiac Function Assessment

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Speckle tracking was used for the measurement of global longitudinal strain (GLS), from three standard apical views, using commercial software (Syngo VVI, Siemens Medical Solutions). After manual tracing of LV endocardial border during end systole, this was automatically tracked throughout the cardiac cycle. GLS was obtained by averaging all 18 segment strain values from the three standard views; abnormal GLS is defined as >−18%.14 (link) Global diastolic strain (DS) was obtained by averaging of all 18 segment strain values and measured according to method published by Ishii et al.15 (link) Calculation of DS was determined as (A−B)/A×100% (A=the systolic value of strain at closure of aortic valve; B=the value of strain at the one-third point of diastole duration) (figure 1). DS rate (DSR) was determined from the average of 18 segments of early DSR.
Yang H., Wang Y., Negishi K., Nolan M, & Marwick T.H. (2016). Pathophysiological effects of different risk factors for heart failure. Open Heart, 3(1), e000339.
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4

Automated Cardiac Strain Analysis

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2-D STE images were imported into a vendor-independent workplace (Syngo VVI, Siemens Medical Solution Inc., USA) for GLS analyses as previously reported.20 (link) The endocardial border was traced manually starting at the mitral annulus during end-systole. Tracking quality of the region of interest was visually inspected and manually adjusted as needed. GLS was averaged from 18 segments obtained of apical 4-, 3-, and 2-chamber views (Figure 1). Strain results were averaged from 3-beat cycles. Twenty-three segments (0.7% of the total) were excluded, no more than 2 segments per chamber view.
Barros-Gomes S., Roger V.L., Pislaru S.V., Kimura T., Pislaru C, & Enriquez-Sarano M. (2021). Cardiac Remodeling in Acute Myocardial Infarction: Prospective Insights from Multimodality Ultrasound Imaging. Echocardiography (Mount Kisco, N.Y.), 38(12), 2032-2042.
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5

Comprehensive Echocardiographic Evaluation of Aortic Stenosis

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All patients underwent a comprehensive echocardiogram with commercially available instruments (Philips Medical Systems, General Electric, and Siemens Medical Solutions). Measurements were obtained according to recommendations and indexed to body surface area.22, 23, 24For quantification of AS, LV outflow tract (LVOT) diameter was measured on parasternal long‐axis views. Pulsed‐wave and continuous‐wave Doppler was used to record velocities across LVOT and aortic valve (AV), respectively. LV‐SVI was measured using the following formula: LVOTVTI×LVOTarea/body surface area. A cutoff ≥35 mL/m2 was considered as preserved LV‐SVI.4, 23, 25, 26 AVA was calculated using the continuity equation and severe AS was defined as AVA ≤1 cm2 or mean AV gradient ≥40 mm Hg. Finally, valvuloarterial impedance (mm Hg·mL−1·m2), a measure of global LV afterload, was calculated as follows27: mean AV gradient+systolic blood pressure/LV‐SVI).
In all patients, LV‐GLS measurements were obtained from gray‐scale images recorded in apical 2, 3, and 4‐chamber views, using offline Velocity Vector Imaging (Syngo VVI; Siemens Medical Solutions, Mountain View, CA). The details of our protocol have been described previously.28 Measurements were made by an investigator blinded to all clinical information. LV‐GLS was not available to physicians at the time of surgical decision‐making.
Goodman A., Kusunose K., Popovic Z.B., Parikh R., Barr T., Sabik J.F., Rodriguez L.L., Svensson L.G., Griffin B.P, & Desai M.Y. (2016). Synergistic Utility of Brain Natriuretic Peptide and Left Ventricular Strain in Patients With Significant Aortic Stenosis. Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 5(1), e002561.
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