Cti rds eclipse st

The whole-body FDG PET/CT was performed as previously described [24 (link)]. Briefly, ¹⁸F-FDG was made automatically by cyclotron (Siemens CTI RDS Eclipse ST; Knoxville, TN, USA) using an Explora FDG4 module. Patients had been fasting for more than 6 h. Scanning was started 1 h after intravenous injection of the tracer (7.4 MBq/kg). The images were acquired on a Siemens biograph 16HR PET/CT scanner with a transaxial intrinsic spatial resolution of 4.1 mm. CT scanning was first initiated from the proximal thighs to the head, with 120 kV, 80–250 mA, pitch 3.6, and rotation time 0.5 s. Image interpretation was carried out on a multimodality computer platform (Syngo; Siemens). Quantification of metabolic activity was acquired using the standardized uptake value (SUV) normalized to bodyweight and the maximum SUV (SUVmax) for each lesion was calculated.

18F-FDG was automatically generated by using Explora FDG4 module on a cyclotron (Siemens CTI RDS Eclipse ST, Knoxville, Tennessee, USA). The purity of radiochemical was over 95%. All patients were required to fast for at least 6 h. Blood glucose level of each patient was measured before the administration of 18F-FDG (dosage: 7.4 MBq/kg), and it should not exceed 10 mmol/L at the time of injection. The patients were comfortably lay down in a quiet and dimly lit room before and after the injection. All patients were scanned on the same instrument. All PET/CT image scans were performed on a Siemens biograph 16HR PET/CT in a 3-dimension, high resolution mode (the transaxial intrinsic spatial resolution was 4.1 mm, full-width at half-maximum in the center of the field of view) after 60 mins after injection. The process of data acquisition was as follows: For attenuation correction, CT scanning was first acquired using a low-dose technique [120 kV, CARE Dose (Siemens), 80–250 mA, pitch 3.6, rotation time 0.5] from the proximal thighs to head. A PET emission scan covering the same transverse field of view was obtained immediately after the CT scan (2–3 minutes/bed). We used a gaussian-filter iterative reconstruction method (iterations 4; subsets 8; image size 168) for the reconstruction of emission images.

¹⁸F-FDG was produced automatically by cyclotron (Siemens CTI RDS Eclipse ST, Knoxville, Tennessee, USA) using the Explora FDG4 module in our center, and the radiochemical purity was over 95%. All patients fasted at least 6 h and the venous blood glucose levels were maintained under 10 mmol/L before ¹⁸F-FDG injection (7.4 MBq/kg). Patients were required to be quiet after injection for approximately 1 h. Siemens biograph 16HR PET/CT scanner (Knoxville, Tennessee, USA) was performed for scanning. The transaxial intrinsic spatial resolution was 4.1 mm (full-width at half-maximum) in the center of the view. CT scanning (120 kV, 80–250 mA, pitch 3.6, rotation time 0.5) from the proximal thighs to the head was first performed for data acquisition, following by a PET emission scan. The acquisition time was 2–3 min/bed. PET image data sets were iteratively reconstructed using the attenuation correction of CT data, and the infused images were displayed on a workstation. The reconstructed images were then converted to a semiquantitative image corrected by the injection dose and the subject’s body weight (SUV).