Synapse recording software system3

Recordings were performed during the first 24 to 48 h after clinical implantation of the temporary depth electrodes. Each electrode lead has a diameter of 1.2 mm and contains 6 low-impedance (1–2 kΩ) ring electrodes with 2 mm height and 5 mm spacing, as well as 10 high-impedance (70–90 kΩ) microelectrodes (50-µm diameter fine wire). The microelectrodes are arranged in groups of 2 or 3, spaced evenly around the circumference of the electrode shaft, between pairs of ring electrodes. The electrodes were connected to AD-TECH CABRIO connectors modified to include a custom unity-gain preamplifier for each microelectrode to reduce noise and motion artifacts. Macroelectrodes bypass the preamplifiers in order to allow for external electrical stimulation. All data reported here are from the high-impedance microelectrode recordings. Microelectrode signals were amplified, sampled at 24 kHz, and digitized by a TUCKER-DAVIS TECHNOLOGIES PZ5M analog-to-digital amplifier connected to an RZ2 digital signal processor. Data were streamed to an RS4 high-speed data storage unit, controlled by SYNAPSE recording software (SYSTEM3, TUCKER-DAVIS TECHNOLOGIES, Alachua, FL, USA).

Recordings were performed during the first 24 to 48 h after clinical implantation of the temporary depth electrodes. Each MM16C electrode lead has a diameter of 1.2 mm and contains 6 low-impedance (1–2 kΩ) ring electrodes with 2-mm height and 5-mm spacing, as well as 10 high-impedance (70–90 kΩ) microwire electrodes (50-μm diameter). The microwire electrodes are arranged in groups of 2 or 3, spaced evenly around the circumference of the electrode shaft, between pairs of ring electrodes. Results reported here are from the microwire electrodes in GPi, VoaVop, and Vim. Therefore, there are either 30 (unilateral) or 60 (bilateral) contacts recorded simultaneously.
The external proximal ends of electrodes were connected to Adtech Cabrio™ connectors, modified to include a custom unity-gain preamplifier for each microwire electrode to reduce noise and motion artifacts. Microwire electrode signals were amplified with a DC-coupled amplifier, sampled at 22 kHz, and digitized by a Tucker-Davis Technologies PZ5M analog-to-digital amplifier connected to an RZ2 digital signal processor. Data were streamed to an RS4 high-speed data storage unit, controlled by Synapse recording software (System3, Tucker-Davis Technologies Inc., Alachua, FL, USA) (Figure 1).