L3.6pl

The normal immortalized human pancreatic epithelial cell line (HPDE6C7) and four human pancreatic cancer cell lines (CFPAC‐1, BXPC3, L3.6pl and Panc‐1) were purchased from the Cell Bank of the Chinese Academy of Sciences (Shanghai, China). All the relevant cells were cultured in DMEM (Sigma‐Aldrich, St. Louis) supplemented with 10% fetal bovine serum (FBS; HyClone, Logan, USA) and kept in a humidified incubator with 5% carbon dioxide at 37°C. The pcDNA3.1‐SNHG14 and pcDNA3.1‐ANXA2 (vector with SNHG4 or ANXA2 overexpression) and empty vectors were from GenePharma (Shanghai, China). The miR‐613 mimic and its negative control (NC), and SNHG14 small interfering RNA (siRNA) (si‐SNHG14) and scrambled siRNA for SNHG14 (si‐NC) were from RiboBio (Guangzhou, China). For cell transfections, cells were grown on 6‐well plates until 60% confluence, and then cells were transfected by miRNA, siRNA, or plasmid using Lipofectamine 2000 reagent (Invitrogen, Carlsbad).

The human pancreatic cancer cell lines (BXPC3, CFPAC-1, Panc-1 and L3.6pl) and HEK-293T cells were purchased from the Cell Bank of the Chinese Academy of Sciences (Shanghai, China). Cells were cultured in Dulbecco's modified Eagle's medium (DMEM, Sigma, St Louis, USA) supplemented with 10% fetal bovine serum (HyClone, GE Healthcare Life Science, Logan, USA) and incubated in a humidified chamber supplemented with 5% CO₂ at 37°C.

The human pancreatic cancer cell lines (BXPC3, CFPAC-1, Panc-1 and L3.6pl) and HEK-293T cells were purchased from the Cell Bank of the Chinese Academy of Sciences (Shanghai, China). Cells were cultured in Dulbecco's modified Eagle's medium (DMEM, Sigma, St Louis, USA) supplemented with 10% fetal bovine serum (HyClone, GE Healthcare Life Science, Logan, USA) and incubated in a humidified chamber supplemented with 5% CO₂ at 37°C.