For patients in all three cohorts, the MR images were acquired using 3 Tesla GE scanners (GE Healthcare, Waukesha, WI, USA) with external 32-channel body array coils without endorectal coils. The imaging protocol included T2-weighted MRI (T2w), diffusion weighted imaging, derived Apparent Diffusion Coefficient (ADC) maps, and dynamic contrast-enhanced imaging sequences. Axial T2w MRI (acquired using a 2D Spin Echo protocol) and ADC maps were used in this study (Table 1 ).
3 tesla ge scanner
Manufactured by GE Healthcare
Sourced in United States
The 3 Tesla GE scanners are magnetic resonance imaging (MRI) machines that use a strong magnetic field and radio waves to generate detailed images of the body's internal structures. The 3 Tesla refers to the strength of the magnetic field, which is three times stronger than a standard MRI scanner. This increased magnetic field allows for faster image acquisition and improved image quality, enabling healthcare professionals to make more accurate diagnoses.
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Lab products found in correlation
7 protocols using 3 tesla ge scanner
1
Prostate MRI Protocol for Cancer
2
MRI Acquisition Protocols for Brain Imaging
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All structural MR images were acquired by two procedures using 3 Tesla GE scanners (GE Healthcare, Chicago, Il) and a T1-weighted 3D-fast spoiled gradient echo sequence. For protocol 1, we examined 106 participants (HC = 58, AVH+ = 30, AVH− = 18) and used the following equipment and parameters: SIGNA HDx with an 8-channel head coil, TR = 6.80 ms, TE = 1.94 ms, flip angle = 20°, slice thickness = 1.0 mm, FOV = 240 × 240 mm, and number of slices = 176. For protocol 2 (total = 98, HC = 59, AVH+ = 28, AVH− = 11), we used DISCOVERY MR750w with a 24-channel head coil, TR = 7.65 ms, TE = 3.10 ms, flip angle = 11°; slice thickness = 1.2 mm, FOV = 256 × 256 mm, and number of slices = 196. There were no procedural differences in the number of groups (χ2 = 1.5, p = 0.5).
3
Multimodal MRI Imaging of Prostate Cancer
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Magnetic resonance images (MRI) were acquired using 3 Tesla GE scanners (GE Healthcare, Waukesha, WI, USA) with external 32-channel body array coils without endorectal coils. The imaging protocol included T2-weighted MRI (T2w), diffusion weighted imaging (DWI), derived Apparent Diffusion Coefficient (ADC) maps and dynamic contrast-enhanced imaging sequences. Axial T2w MRI (acquired using a 2D Spin Echo protocol) and ADC maps were used in this study (see characteristics in Table 3 ).
The excised prostates were fixed in formalin and embedded in paraffin and then serially sectioned using customized 3D-printed molds with slice orientation and thickness matching that of T2w images, followed by staining with hematoxylin and eosin. All stained slices were scanned at 20× magnification (pixel size 0.5 μm) to generate digitized whole-mount histopathology images.
The excised prostates were fixed in formalin and embedded in paraffin and then serially sectioned using customized 3D-printed molds with slice orientation and thickness matching that of T2w images, followed by staining with hematoxylin and eosin. All stained slices were scanned at 20× magnification (pixel size 0.5 μm) to generate digitized whole-mount histopathology images.
4
Functional MRI Acquisition Protocols
5
Longitudinal Brain MRI Acquisition
6
Structural MRI Acquisition and Preprocessing
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Three-dimensional structural MRI scans were acquired on a 3-Tesla GE scanner (GE Medical Systems, Milwaukee, WI) using a magnetization prepared rapid gradient echo (MPRAGE) sequence (repetition time 7.28 ms, echo time 2.74 ms, 120–136 slices, resolution 0.859 × 0.859 × 1.2 mm). Preprocessing included intensity nonuniformity normalization52 (link) and rigid alignment to MNI space.
7
Multimodal Neuroimaging: Acquisition and Preprocessing
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Images were acquired on a 3-Tesla GE scanner equipped with an 8-channel headcoil. T1-weighted whole-brain axial images were obtained with 1-mm isotropic voxels using array spatial sensitivity encoding technique and fast spoiled gradient-recall (3D-FSPGR) (TR/TE/flip angle = 8.16 ms/3.18 ms/12°, FOV = 256 mm2, 1 mm slice thickness, 172 slices, 256 × 256 matrix). Functional images were obtained using the standard echo-planar pulse sequence (TR/TE/flip angle = 2000 ms/27 ms/60°, FOV = 256 mm2, 64 × 64 matrix, 3.8 mm thickness, 34 oblique axial slices, no interslice gap).
Images were preprocessed using the CONN toolbox (https://sites.google.com/view/conn/ ). After discarding the first three volumes, functional images were slice-time and head-motion corrected, and co-registered to each participant’s structural image. Structural images were segmented, bias corrected and spatially normalized to the Montreal Neurological Institute (MNI) space. The normalization parameters were also applied to normalize the functional images. Finally, functional images were smoothed with an 8-mm FWHM Gaussian kernel.
Images were preprocessed using the CONN toolbox (
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