The VIPER software was developed at the Calvary Mater Newcastle Hospital (CMNH) for EP-ID-based 3D dose distribution reconstruction onto a virtual water phantom [25 (
link), 26 (
link)]. VIPER can be used for either 2D or 3D dose reconstruction to perform dosimetric verification of the individual fields or composite plan, respectively. However, it was shown by Kruse that single field planar verification is insensitive and not sufficient to detect important dosimetric inaccuracies of the overall IMRT plan [27 (
link)]. Therefore, 3D reconstructed dose-based verification is better than using 2D reconstructed doses. The resulting 3D dose can be compared with the corresponding dose distribution computed by a treatment planning system (TPS) to be evaluated.
Instructions provided by CMNH were followed to obtain a VIPER (v. 3.10 beta, May 2019) calibration tailored to our facility. VIPER was configured for 6 MV beams from a Varian
CLINAC 2100 CD linac (Varian Medical Systems, Palo Alto, CA), equipped with the
Millennium 120 multileaf collimator (MLC) and the
PortalVision aS500 EPID. Repetition rate of 600 monitor units per minute was used.
The validation and feasibility of VIPER for SRS plan verification were described by our group in a recent publication [24 (
link)].
Calvo-Ortega J.F., Greer P.B., Moragues-FemenÃa S., Pozo-Massó M, & Casals-Farran J. (2022). Verification of stereotactic radiosurgery plans for multiple brain metastases using a virtual phantom-based procedure. Reports of Practical Oncology and Radiotherapy, 27(3), 449-457.