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Anti rac1 2

Manufactured by Cell Signaling Technology
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Sourced in United States

Anti-Rac1/2 is a primary antibody that recognizes the Rac1 and Rac2 proteins. Rac1 and Rac2 are small GTPases that play a role in regulating the actin cytoskeleton and cellular processes. This antibody can be used to detect and analyze the expression of Rac1 and Rac2 proteins in various cell and tissue samples.

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Lab products found in correlation

Anti p47phox, by Santa Cruz Biotechnology (2 mentions)

Close spelling variants of this product

Anti-Rac1 (10 citations) Anti-Rac1/2/3 (4 citations) RAC1/2 (2 citations)

2 protocols using anti rac1 2

1

Cytosol to Membrane Translocation of p47phox and Rac1/2

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Cytosol to membrane translocation of p47phox, which is essential for NADPH oxidase activation, and Rac1/2 (small G protein necessary for NADPH oxidase activity) was assessed in VSMCs. Cells were lysed and fractionated to obtain cytosol- and membrane-enriched fractions. Western blotting was performed as described using anti-p47phox (Santa Cruz Biotechnology, TX-USA) and anti-Rac1/2 (Cell Signaling, MA-USA). Translocation was determined as the ratio of protein expression in membrane to cytosolic fractions.
Bruder-Nascimento T., Callera G.E., Montezano A.C., de Chantemele E.J., Tostes R.C, & Touyz R.M. (2019). Atorvastatin inhibits pro-inflammatory actions of aldosterone in vascular smooth muscle cells by reducing oxidative stress. Life sciences, 221, 29-34.
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2

Cytosol to Membrane Translocation of p47phox and Rac1/2

Check if the same lab product or an alternative is used in the 5 most similar protocols
Cytosol to membrane translocation of p47phox, which is essential for NADPH oxidase activation, and Rac1/2 (small G protein necessary for NADPH oxidase activity) was assessed in VSMCs. Cells were lysed and fractionated to obtain cytosol- and membrane-enriched fractions. Western blotting was performed as described using anti-p47phox (Santa Cruz Biotechnology, TX-USA) and anti-Rac1/2 (Cell Signaling, MA-USA). Translocation was determined as the ratio of protein expression in membrane to cytosolic fractions.
Bruder-Nascimento T., Callera G.E., Montezano A.C., de Chantemele E.J., Tostes R.C, & Touyz R.M. (2019). Atorvastatin inhibits pro-inflammatory actions of aldosterone in vascular smooth muscle cells by reducing oxidative stress. Life sciences, 221, 29-34.
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