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Mitoxantrone

Manufactured by Yuanye Bio-Technology

Mitoxantrone is a laboratory reagent used in scientific research. It is a synthetic anthraquinone derivative that intercalates with DNA and acts as a topoisomerase II inhibitor. Mitoxantrone is commonly used in cell biology and molecular biology experiments to study DNA interactions and cellular processes.

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2 protocols using mitoxantrone

1

Biochemical Assay Reagents Procurement

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Compounds, such as lurasidone, paliperidone, mitoxantrone, and risperidone, were purchased from Yuanye Biotech or Meilun. PMA/ionomycin was purchased from Beyotime Biotechnology. Anti-CYLD antibody was purchased from Cell Signaling Technology. Anti-β-actin antibody and HRP-labeled goat anti-rabbit or goat anti-mouse secondary antibody were purchased from TransGen Biotech.
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2

Investigating Multidrug Resistance Mechanisms

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Metyrapone, ketoconazole, and mitoxantrone were purchased from Shanghai Yuanye Bio-Technology Co., Ltd (Shanghai, China). Ko143 was purchased from MedChemExpress (Monmouth Junction, NJ). Anti-ABCG2 (N338) and anti-β-tubulin polyclonal antibodies were purchased from Bioworld Technology (Louis Park, MN). DNA transfection reagents were purchased from Vazyme Biotech Co., Ltd (Nanjing, China). An RNA transfection reagent was purchased from Zeta Life (Menlo Park, CA). All other chemicals were of analytical grade and obtained from standard suppliers unless mentioned otherwise.
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