Log In Sign up
The largest database of trusted experimental protocols

Advia centaur platform

Manufactured by Siemens
Visit Supplier
Sourced in United States

The ADVIA Centaur platform is an automated immunoassay analyzer designed for in-vitro diagnostic testing. It is capable of performing a wide range of immunoassay tests, including those for hormones, infectious diseases, and therapeutic drug monitoring. The platform is equipped with automated sample handling and advanced analytical capabilities to provide accurate and reliable results.

Automatically generated - may contain errors

Lab products found in correlation

Immunocap isac, by Thermo Fisher Scientific (1 mentions) Prism v7, by GraphPad (1 mentions) Spss statistics v24, by IBM (1 mentions) Triglycerides gpopap, by Roche (1 mentions) Hdl c plus, by Roche (1 mentions) Gluco quant, by Roche (1 mentions) Immulite 2000, by Siemens (1 mentions) Eclia, by Roche (1 mentions)

4 protocols using advia centaur platform

1

Measurement of Allergen-specific IgE and IgG4

Check if the same lab product or an alternative is used in the 5 most similar protocols
Allergen‐specific IgE was measured using the ADVIA Centaur platform (Siemens Healthcare Diagnostics, Inc, Tarrytown, NY, United States) according to standard methods. Values provided are the sum of Phl p 1 and Phl p 5. Phl p 1‐ and p 5‐specific IgG4 was determined by ELISA.1 All samples were tested by ImmunoCAP‐ISAC (Thermo Fisher Scientific, Uppsala, Sweden) to investigate sensitization profiles.
Statistical analysis was performed using IBM SPSS Statistics, v24. As data did not follow normality, Mann‐Whitney U test was applied to test the differences in the treatment at each time point. On the other hand, Friedman test was used to obtain differences due to the time in each treatment. Moreover, Wilcoxon test was performed for pair‐based comparisons. In all cases, P‐values < .05 were considered significant. Data were represented using violin plots showing sample median ± max and min values with Prism v7.0 software (GraphPad Software, La Jolla, CA).
Barker‐Tejeda T.C., Bazire R., Obeso D., Mera‐Berriatua L., Rosace D., Vazquez‐Cortes S., Ramos T., Rico M.D., Chivato T., Barbas C., Villaseñor A., Escribese M.M., Fernández‐Rivas M., Blanco C, & Barber D. (2020). Exploring novel systemic biomarker approaches in grass‐pollen sublingual immunotherapy using omics. Allergy, 76(4), 1199-1212.
+ Open protocol
+ Expand
2

Fasting Lipid and Hormone Profiling

Check if the same lab product or an alternative is used in the 5 most similar protocols
Levels of fasting lipids [total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), and triglycerides (TGs)] were measured using in vitro enzyme test kits on a Hitachi system (Cholesterol CHOD-PAD, HDL-C plus, Triglycerides GPO-PAP, and LDL-C plus; Roche Diagnostics GmbH, Mannheim, Germany). The ratios of LDL-C to HDL-C and TGs to HDL-C were calculated as independent markers for cardiovascular risk (27 (link)).
Insulin was measured using an electrochemiluminescence immunoassay (IMMULITE 2000; Siemens Healthcare Diagnostics, NJ, USA). Fasting glucose was measured by enzymatic absorption photometry using a cobas® 8000 analyzer (via Gluco-Quant; Roche Diagnostics GmbH). Insulin resistance (IR) was defined by using the homeostatic model assessment (HOMA) index, compared with specific pediatric percentiles according to sex and pubertal stage (28 ), and defined by a fasting glucose-to-insulin ratio (FGIR) of less than 7 (29 (link)).
Measurements of luteinizing hormone (LH), follicle-stimulating hormone (FSH), and estradiol (E2) were taken using the ADVIA Centaur® platform (Siemens Healthcare Diagnostics, NJ, USA) using the chemiluminescent immunometric method.
All biochemical analyses were carried out in the same laboratory.
Bruzzi P., Valeri L., Sandoni M., Madeo S.F., Predieri B., Lucaccioni L, & Iughetti L. (2022). The impact of BMI on long-term anthropometric and metabolic outcomes in girls with idiopathic central precocious puberty treated with GnRHas. Frontiers in Endocrinology, 13, 1006680.
+ Open protocol
+ Expand
3

Biomarker Assessment in Cardiovascular Disease

Check if the same lab product or an alternative is used in the 5 most similar protocols
Venous blood samples for NPs (brain natriuretic peptide (BNP) at the Pavia Center and/or N-terminal-proBNP (NT-proBNP) at the Palermo and Montescano centers) were drawn on the day of echocardiography. Chilled ethylenediaminetetraacetic acid (EDTA) tubes were centrifuged immediately at 4000 g (48°C) for 15 minutes. Separated plasma samples were processed by immunofluorescence assay (ADVIA Centaur platform, Siemens Healthcare Diagnostics S.R.L., Milan, Italy, for BNP; ECLIA; Roche Diagnostics; Indianapolis, Indiana, for NT-proBNP). For BNP, the lower assay detection limit was 1 pg/mL, while for NT-proBNP, the measuring range was 5–35000 pg/mL. We measured serum troponin I using a high-sensitive troponin I assay (Centaur TnI-Ultra/Siemens Medical Solution Diagnostics, NY). In this assay, the lower limit of detection is 0.006 ng/mL and the lowest concentration at which the coefficient of variation was <10% was 0.03 ng/ml, while the intra-assay and interassay CVs were 3.5% (n=4) and 4.2% (n=4), respectively, in a sample with a troponin I concentration of 0.03 ng/mL.
Falletta C., Clemenza F., Klersy C., Agnese V., Bellavia D., Di Gesaro G., Minà C., Romano G., Temporelli P.L., Dini F.L., Rossi A., Raineri C., Turco A., Traversi E, & Ghio S. (2019). Additive Value of Biomarkers and Echocardiography to Stratify the Risk of Death in Heart Failure Patients with Reduced Ejection Fraction. Cardiology Research and Practice, 2019, 1824816.
+ Open protocol
+ Expand
4

Allergen-specific IgE and IgG Measurement

Check if the same lab product or an alternative is used in the 5 most similar protocols
Allergen‐specific IgE (to the major allergens Phleum p 1 and p 5) was measured using the ADVIA Centaur platform (Siemens Healthcare Diagnostics, Inc., Tarrytown, NY. United States) according to standard methods. Phleum p 1‐ and p 5‐specific IgG4 and IgG1 were determined by ELISA.11
Varona R., Ramos T., Escribese M.M., Jimeno L., Galán A., Würtzen P.A., Vega F., Marín A., Martín S., Carrera A.C., Blanco C, & Barber D. (2018). Persistent regulatory T‐cell response 2 years after 3 years of grass tablet SLIT: Links to reduced eosinophil counts, sIgE levels, and clinical benefit. Allergy, 74(2), 349-360.
+ Open protocol
+ Expand

About PubCompare

Our mission is to provide scientists with the largest repository of trustworthy protocols and intelligent analytical tools, thereby offering them extensive information to design robust protocols aimed at minimizing the risk of failures.

We believe that the most crucial aspect is to grant scientists access to a wide range of reliable sources and new useful tools that surpass human capabilities.

However, we trust in allowing scientists to determine how to construct their own protocols based on this information, as they are the experts in their field.

Ready to get started?

Sign up for free.
Registration takes 20 seconds.
Available from any computer
No download required

Sign up now

Revolutionizing how scientists
search and build protocols!