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Discovery 3t scanner

Manufactured by GE Healthcare

The Discovery 3T scanner from GE Healthcare is a magnetic resonance imaging (MRI) system designed to provide high-quality images. It operates at a magnetic field strength of 3 Tesla, which enables the acquisition of detailed anatomical and functional information. The scanner is equipped with advanced imaging capabilities to support a wide range of clinical applications.

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4 protocols using discovery 3t scanner

1

High-Resolution T1-Weighted Imaging Protocol

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For the high-resolution T1-weighted imaging (T1WI) sequences, we used a GE Discovery 3T scanner with an 8-channel head coil containing 192 slices with a repetition time of 6.8 ms, echo time of 3 ms, flip angle of 12°, 1-mm slice thickness, 256 × 256 matrix, and field of view of 216 × 216. We checked the image quality and excluded data that featured visible head motion artifacts and signal noises caused by the skull base.
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2

T1 Measurements of 13C-Urea Samples

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13C T1 measurements were collected using the GE Discovery 3T scanner inside the 13C/1H volume resonator. Four reference samples were measured individually: non-lyophilized urea in H2O without Gd, non-lyophilized urea in H2O with Gd, twice lyophilized urea in D2O without Gd, and twice lyophilized urea in D2O with Gd. A non-selective spectroscopy method was used to acquire variable flip angle measurements for calculating the T1 for 13C-urea in these mixtures.
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3

Brain MRI Acquisition Protocol

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Brain MRI scans were performed on a GE Discovery 3 T scanner at Pennington Biomedical Research Center. A 32-channel phased array head coil was used. Sequences included: (1) T1-weighted 3D BRAVO (voxel size, 0.94 × 0.94 × 1.2 mm3; voxel array, 256 × 256 × 140; flip angle, 12°; NEX, 2; TI, 450; bandwidth, 31.25; total run time, 6:41); (2) axial 2D FLAIR (voxel size, 1.07 × 1.07 × 2 mm3; voxel array, 224 × 224 × 69; flip angle, 160°; TE, 95 ms; TR, 9000 ms; TI, 2250 ms; NEX, 1; bandwidth, 31.25; total run time, 4:58); (3) axial 2D gradient echo EPI BOLD (voxel size, 3 × 3 × 3 mm3; voxel array, 64 × 64 × 43; flip angle, 90°; TE, 35 ms; TR, 2500 ms; NEX, 1); (4) axial 2D single-shot spin echo EPI diffusion (30 independent gradient directions; 1 B0 image; 1.875 × 1.875 × 3.6 mm3 voxel size; 128 × 128 × 56 voxel array; TE: minimum; TR: 8000). Participants wore a respiratory monitoring belt and pulse oxygenation sensor to model respiratory and cardiac effects on the BOLD signal19 (link).
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4

Multimodal MRI Protocol for Imitation and Observation

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MRI scanning was conducted on a General Electric Discovery 3-T scanner at the Centre for Addiction and Mental Health, on a General Electric Signa 3-T scanner at Zucker Hillside Hospital, and on a Siemens Tim Trio 3-T scanner at the Maryland Psychiatric Research Center. The imitate/observe task was part of a longer multimodal MRI protocol to which each participant consented. Each block of the task (imitate or observe) used an echo-planar imaging scan (110 repetition times of 3 seconds, echo time 30 ms, voxel size 3 mm isotropic, 50 slices, 64364 matrix with field of view=192 mm, flip angle=77°). A fast-gradient echo anatomical T 1 scan was collected for use in the preprocessing pipeline (repetition time, 2300 ms, 0.9 mm isotropic, no gap, interleaved ascending).
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