Log In Sign up
The largest database of trusted experimental protocols

Z lytescreen

Manufactured by Thermo Fisher Scientific
Visit Supplier

The Z'LyteScreen is a versatile lab equipment product designed for sensitive cell-based assays. It utilizes a proprietary fluorescence-based detection technology to enable reliable and accurate measurements of cellular responses. The core function of the Z'LyteScreen is to provide a platform for researchers to conduct various cell-based experiments and analyses.

Automatically generated - may contain errors

Lab products found in correlation

Lanthascreen eu kinase binding assay, by Thermo Fisher Scientific (1 mentions)

2 protocols using z lytescreen

1

Kinase Profiling of INX-315

Check if the same lab product or an alternative is used in the 5 most similar protocols
INX-315 was first evaluated in the SelectScreen Biochemical Kinase Profiling at Thermo Fisher Scientific (Madison, WI). The primary screen consisted of INX-315 dosed at a single concentration of 100 nmol/L in 1% DMSO across each platform within the SelectScreen array of assays, LanthaScreen Eu Kinase Binding Assay; AdaptaScreen; and Z'LyteScreen using preestablished conditions at Thermo Fisher Scientific as shown in Supplementary Table S2. All target kinases that responded to greater than 90% inhibition in primary screen were retested as individuals for IC50 determination shown in Supplementary Fig. S1. The follow-up screen consisted of 10-point dose–response curves for INX-315 from 1 μmol/L to 0.0495 nmol/L.
Dietrich C., Trub A., Ahn A., Taylor M., Ambani K., Chan K.T., Lu K.H., Mahendra C.A., Blyth C., Coulson R., Ramm S., Watt A.C., Matsa S.K., Bisi J., Strum J., Roberts P, & Goel S. (2023). INX-315, a Selective CDK2 Inhibitor, Induces Cell Cycle Arrest and Senescence in Solid Tumors. Cancer Discovery, 14(3), 446-467.
+ Open protocol
+ Expand
2

Assessing RSK2 Kinase Activity

Check if the same lab product or an alternative is used in the 5 most similar protocols
RSK2 kinase assays performed as described (32 (link)). The kinase screen was performed using the ZLYTE screen (Thermo Fisher Scientific, Inc.).
Ludwik K.A., Campbell J.P., Li M., Li Y., Sandusky Z.M., Pasic L., Sowder M.E., Brenin D.R., Pietenpol J.A., O’Doherty G.A, & Lannigan D.A. (2016). Development of a RSK Inhibitor as a Novel Therapy for Triple Negative Breast Cancer. Molecular cancer therapeutics, 15(11), 2598-2608.
+ Open protocol
+ Expand

About PubCompare

Our mission is to provide scientists with the largest repository of trustworthy protocols and intelligent analytical tools, thereby offering them extensive information to design robust protocols aimed at minimizing the risk of failures.

We believe that the most crucial aspect is to grant scientists access to a wide range of reliable sources and new useful tools that surpass human capabilities.

However, we trust in allowing scientists to determine how to construct their own protocols based on this information, as they are the experts in their field.

Ready to get started?

Sign up for free.
Registration takes 20 seconds.
Available from any computer
No download required

Sign up now

Revolutionizing how scientists
search and build protocols!