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Ominpaque 350

Manufactured by GE Healthcare
Sourced in Italy

Omnipaque 350 is a non-ionic, water-soluble iodinated contrast medium used for various diagnostic imaging procedures. It is a radiopaque agent that enhances the visibility of internal structures and organs during radiologic examinations. Omnipaque 350 is presented as a sterile, clear, colorless to slightly yellow, aqueous solution for injection.

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4 protocols using ominpaque 350

1

Pulmonary CT Angiography Protocol

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All patients were scanned using 64-detector row (Light speed VCT GE Healthcare). Scan parameters were as follows: matrix 512X512, tube voltage 80-120, pitch 1,375 rotation time 0.6s. All imaging was acquired in a single breath hold in a caudocranial direction, started from the posterior costophrenic angles and ends at the lung apex. Patient received 40-100 ml iodinated contrast medium with 350 mgI/ml concentration (ominpaque350, GE Healthcare or xenetix350, Guerbet) with an injection rate of 5ml/sec. In 2014 the image delay was determined by automatic bolus tracking and selecting the best image time with the max contrast filing in the pulmonary artery. On the other hand the 2015 protocol has added waiting for five seconds before starting the scan for bolus tracking, as the contrast medium could not have reached the pulmonary artery in the first 5 sec and scanning in this time will be an addition of non useful radiation to the patient (Fig.1). Contrast medium volume was calculated to be equal to the product of the scan time delay and the flow rate. Adaptive Statistical Iterative Reconstruction (ASIR) algorithm was used; the image acquisition was modified by 30%.
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2

Chest CT Imaging Protocol for Lung Evaluation

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Chest CT scans were performed with different multi-slice CT systems: Aquilion ONE (Toshiba Medical Systems, Otawara, Japan); GE Revolution, GE Discovery CT750 HD, or LightSpeed VCT (GE Healthcare, Milwaukee, WI, USA); and Brilliance iCT (Philips Healthcare, Cleveland, OH, USA). Parameters used for scans without intravenous contrast included a peak x-ray tube voltage of 120 kV, automatic tube current modulation (300–500 mAs), and slice thickness of 0.625 to 1.25 mm. The protocol for contrast-enhanced included a peak x-ray tube voltage of 120 kV, automatic tube current modulation (500–650 mAs), and slice thickness of 0.625 to 1.0 mm. A total of 80–100 ml iodinated contrast material (Iomeron 400, Bracco Imaging SpA, Milan, Italy; or Ominpaque 350, GE Healthcare, United States) was injected intravenously at a rate of 5 ml/s and followed by 20–30ml of saline chaser at a rate of 4–5 ml/s. Images were reconstructed using standard lung filters specific to each CT vendor. All scans were obtained in the supine position during inspiratory breath-hold.
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3

Contrast-Enhanced Chest CT Imaging

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Chest CT scans were performed with different multi-slice CT systems: Aquilion ONE (Toshiba Medical Systems, Otawara, Japan); GE Revolution, GE Discovery CT750 HD, or LightSpeed VCT (GE Healthcare, Milwaukee, WI, USA); and Brilliance iCT (Philips Healthcare, Cleveland, OH, USA). Parameters used for scans without intravenous contrast included a peak x-ray tube voltage of 120 kV, automatic tube current modulation (300-500 mAs), and slice thickness of 0.625 to 1.25 mm. The protocol for contrast-enhanced included a peak x-ray tube voltage of 120 kV, automatic tube current modulation (500-650 mAs), and slice thickness of 0.625 to 1.0 mm. A total of 80–100 ml iodinated contrast material (Iomeron 400, Bracco Imaging SpA, Milan, Italy; or Ominpaque 350, GE Healthcare, United States) was injected intravenously at a rate of 5 ml/s and followed by 20-30ml of saline chaser at flow are of 4-5 ml/s. Images were reconstructed using standard lung filters specific to each CT vendor. All scans were obtained in the supine position during inspiratory breath-hold.
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4

Chest CT Imaging Protocol for COVID-19

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Chest CT scans were conducted using various multi-slice CT systems, including the Aquilion ONE (Toshiba Medical Systems, Otawara, Japan), GE Revolution, GE Discovery CT750 HD, or LightSpeed VCT (GE Healthcare, Milwaukee, WI, USA), and Brilliance iCT and Incisive CT (Philips Healthcare, Cleveland, OH, USA). Scans without intravenous contrast utilized a peak x-ray tube voltage of 120 kV, automatic tube current modulation (300-500 mAs), and a slice thickness of 0.625 to 1.25 mm. The contrast-enhanced protocol consisted of a peak x-ray tube voltage of 120 kV, automatic tube current modulation (500-650 mAs), and a slice thickness of 0.625 to 1.0 mm. Iodinated contrast material (Iomeron 400 and 350, Bracco Imaging SpA, Milan, Italy; or Ominpaque 350, GE Healthcare, United States) totaling 80-100 ml was injected intravenously at a rate of 5 ml/s and followed by 20-30ml of saline chaser at a flow rate of 4-5 ml/s. Standard lung filters specific to each CT vendor were used to reconstruct the images. All scans were obtained while patients were in the supine position during an inspiratory breathhold.
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