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Icon scanner

Manufactured by Bruker
Sourced in Germany

The ICON scanner is a compact magnetic resonance imaging (MRI) system designed for materials analysis and small-sample imaging. It provides high-quality, non-invasive imaging of a variety of samples, including polymers, composites, and porous media. The ICON scanner employs permanent magnets and features a simple, user-friendly interface.

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3 protocols using icon scanner

1

High-Resolution MRI Imaging of SCN Ablated Mice

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Screening of SCN ablated mice was performed using a Bruker ICON scanner (Bruker, Karlsruhe, Germany). RARE (Rapid Acquisition with Refocused Echoes) sequence was used to acquire coronal, sagittal and axial slices (5 slices in each orientation) with the following parameters: RARE factor=8, TE=85ms, TR=2500ms, resolution = 156x156x500µm3 (30 averages). For high-quality images a 9.4T BioSpec scanner (Bruker, Karlsruhe, Germany) was employed. This operates with Paravision 6.0.1 software and interfaced with an Avance IIIHD console. Anatomical images (16 axial and 13 sagittal slices) were acquired using a RARE (Rapid Acquisition with Refocused Echoes) sequence with RARE factor=8, TE=36ms, TR=2200ms and resolution of 80x80x500µm3 (12 averages).
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2

High-Resolution MRI Imaging of SCN Ablated Mice

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Screening of SCN ablated mice was performed using a Bruker ICON scanner (Bruker, Karlsruhe, Germany). RARE (Rapid Acquisition with Refocused Echoes) sequence was used to acquire coronal, sagittal and axial slices (5 slices in each orientation) with the following parameters: RARE factor=8, TE=85ms, TR=2500ms, resolution = 156x156x500µm3 (30 averages). For high-quality images a 9.4T BioSpec scanner (Bruker, Karlsruhe, Germany) was employed. This operates with Paravision 6.0.1 software and interfaced with an Avance IIIHD console. Anatomical images (16 axial and 13 sagittal slices) were acquired using a RARE (Rapid Acquisition with Refocused Echoes) sequence with RARE factor=8, TE=36ms, TR=2200ms and resolution of 80x80x500µm3 (12 averages).
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3

Adsorption of Emulsion Droplets on Mica Substrate

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A 5 µL volume of the freshly prepared NFPh emulsion, prepared as described in Section 4.1, was dispensed onto freshly cleaved mica. Mica surface (0.15 mm thick, sized 15 × 15 mm, TipsNano, Zelenograd, Russia) was used as a substrate for non-covalent adsorption.
The emulsion droplet was incubated on the mica substrate surface for 10 min. Then, the substrate was washed with 1 mL of deionized water, which was obtained using a Simplicity UV system (Millipore, Molsheim, France). The washed substrate was dried in air and subjected to AFM scanning.
The AFM images of nanosized particles were obtained with a Dimension atomic force microscope equipped with an Icon scanner (Bruker, Billerica, MA, USA). The instrument is a part of the Avogadro unique research facility (http://avo.ibmc.msk.ru/ (accessed on 1 October 2023)). Scanning was carried out in the tapping mode. A short cantilever holder was used; the measurements were conducted in air. The images were recorded using the NanoScope 9.4 software (Bruker, Billerica, MA, USA). AFM images were processed using the standard NanoScope Analysis 2.0 software (Bruker, Billerica, MA, USA), Gwyddion 2.62, and Femtoscan Online software 4.8 (LLC Scientific and Production Enterprise “Center for Advanced Technologies”, Moscow, Russia; www.nanoscopy.net/en/Femtoscan-V.shtm (accessed on 6 May 2021)).
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