Avanto 1.5 tesla

Subjects were scanned with a Siemens Avanto 1.5 Tesla magnetic resonance imaging scanner with a 32-channel head coil, with sounds presented via Sensimetrics S14 earbuds, padded around the ear with NoMoCo memory foam cushions. Functional data were collected using a slow event-related design with sparse temporal sampling to allow presentation of auditory stimuli in quiet. We used an echo planar image sequence, with 40 slices, slice time 85 ms, slab tilted to capture the entire cerebrum and dorsal cerebellum, ascending sequential acquisition; 3 × 3 × 3 mm voxel size; silent stimulus and response period = 8.7 s, volume acquisition time = 3.4 s, total inter-trial interval = 12.1 s, flip angle = 90 degrees, bandwidth = 2298 Hz/pixel, echo time (TE) = 50 ms. After collecting functional runs, a high-resolution T1-weighted structural scan was collected (MPRAGE, 176 slices, sagittal acquisition, 2x GRAPPA acceleration, 1 mm isotropic voxels, acquisition matrix = 224 × 256).

The scanner was a Siemens Avanto 1.5 Tesla with a knee coil. Structural scans and clinically required images were always acquired first. For details of the acquisition parameters, structural resolution and analysis of image data, see Supporting information Methods (Data S1).

MRI (Table 1) was performed on a Siemens Avanto 1.5 Tesla (Siemens, Erlangen, Germany). b-Values for DTI were 0, 1000 s/mm² and 12 diffusion directions were used. DTI data was post-processed using MITK Diffusion [22 (link)] to generate voxel-wisely calculated maps of axial, mean and radial diffusivity (AD, MD and RD), which were derived from the eigenvalues λ₁, λ₂ and λ₃ of the diffusion tensor:
$\mathrm{A}\mathrm{D}={\mathrm{\lambda }}_1;\mathrm{R}\mathrm{D}=\frac{{(\mathrm{\lambda }}_2+{\mathrm{\lambda }}_3)}{2};\mathrm{M}\mathrm{D}=\frac{{({\mathrm{\lambda }}_1+\mathrm{\lambda }}_2+{\mathrm{\lambda }}_3)}{3};{{\mathrm{\lambda }}_1\ge \mathrm{\lambda }}_2\ge {\mathrm{\lambda }}_3$