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Biograph mmr 3 t scanner

Manufactured by Siemens
Sourced in Germany

The Biograph mMR 3 T scanner is a magnetic resonance imaging (MRI) system designed for medical research applications. It provides a 3 Tesla magnetic field strength and is capable of acquiring high-resolution anatomical and functional images. The system is intended for use in clinical research settings to support the advancement of medical knowledge and understanding.

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3 protocols using biograph mmr 3 t scanner

1

Multimodal Brain Imaging with 3T MRI

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T1-, T2-, and diffusion-weighted images were acquired with a 3.0-Tesla Siemens Biograph mMR 3 T scanner (Siemens Healthcare Sector, Germany) with a 16-channel head coil. T1-weighted structural images were acquired with the following parameters: echo time (TE) = 1.89 ms, repetition time (TR) = 1670 ms, field of view (FOV) = 250 mm, flip angle = 9°, matrix = 256 × 256, voxel size = 1.0 × 1.0 × 1.0 mm3, and 208 slices. T2-wighted images were acquired with the following parameters: 47 axial slices, slice thickness = 3 mm, TR = 5000 ms, TE = 81 ms, FOV = 220 × 220 mm2, flip angle = 124°.
Axial diffusion-weighted single-shot echo-planar images were acquired with the following parameters: TE = 92.0 ms, TR = 9500 ms, FOV = 230 mm3, voxel size = 2.0 × 2.0 × 2.0 mm3, 66 axial slices, slice gap = 0 mm, and b-factor = 1000 sec/mm2. A baseline image without diffusion volume was used as a reference image, and diffusion-weighted images were acquired from 67 different directions. All axial images were acquired parallel to the anterior-posterior commissure line.
Preprocessing steps included skull stripping and eddy -current correction using the FMRIB software Library(FSL)(Jenkinson et al., 2012 (link)). Motion correction was done by the affine alignment to the b0 image.
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2

Cardiac Stroke Volume Measurement by MRI

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SV was measured by MRI (Biograph mMR 3-T scanner, Siemens, Erlangen, Germany) once during the BDC phase (BDC-4), twice during the HDT phase (HDT21 and HDT58), and once during the recovery phase (R + 4, see Fig. 1). The subject was placed inside the MRI machine in supine 0° position. 2D PC-MRI images (30 frames per cardiac cycle, spatial resolution 1.4 × 1.4 × 5.0 mm3 (link)) were acquired during spontaneous breathing using a plane perpendicular to the centerline at a proximal site of the ascending aorta, with three-directional velocity encoding (x, y: 80 cm/s; z: 150 cm/s). SV was computed as the time integral of the flow rate in the systolic ejection period. More information concerning this protocol is given by Caiani and coworkers31 .
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3

Neuropsychological Assessment and Resting-State fMRI

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This study has been conducted at the IRCCS Synlab SDN (Naples, Italy). An expert neuropsychologist performed the neuropsychological assessment for each participant. Such an assessment included a self-report evaluation of subjective sleep quality (PSQI), an assessment of depression and anxiety, and an evaluation of verbal and visuospatial working memory performance. After the neuropsychological assessment, each participant underwent a resting-state fMRI experimental protocol. MR images were acquired using a Biograph mMR 3T scanner (Siemens Healthcare, Erlangen, Germany) and a 12-channel head coil. An ad hoc acquisition protocol was devised, which included the following structural and functional sequences: (1) 3D T1-Magnetisation Prepared Rapid Acquisition Gradient Echo (MPRAGE), voxel size 0.8 × 0.8 × 0.8 mm3, Field of View (FOV) 214 × 214 mm, TR/TE/TI = 2,400/2.25/1,000 ms, scan time 5:03; and (2) Resting-state fMRI, Echo Planar Imaging-Gradient Echo sequence (EPI-GRE), voxel-size 4 × 4 × 4 mm3, TR/TE = 1,000/21.4 ms, 350 measurements, bandwidth: 2,230 Hz, scan time 6:02.
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