Tetrahydrocannabivarin

Commercial medical cannabis extracts (“cannabis oils”) and commercial inflorescences, produced by various Israeli licensed producers, were obtained from Bazelet Pharma (Or Akiva, Israel). Cannabinoid standards: cannabinol (CBN), cannabichromene (CBC), cannabichromenic acid (CBCA), cannabigerolic acid (CBGA), cannabigerol (CBG), cannabidiolic acid (CBDA), cannabidiol (CBD), delta-9-tetrahydrocannabinoic acid (THCA) and delta-9-tetrahydrocannabinol (THC) were purchased from Cerrilliant (Cerilliant Corporation, Round Rock, TX, USA). Cannabidivarin (CBDV), Cannabidivarinic Acid (CBDVA), tetrahydrocannabivarin (THCV), and delta-8-tetrahydrocannabinol (Δ8-THC) were purchased from Restek (Bellefonte, PA, USA). All cannabinoid standards are Certified Reference Materials (CRM) standards, at 1000 µg/mL in methanol. Terpene standards were purchased from Restek (Bellefonte, PA, USA), Merck (Rosh-Ha’ayin, Israel), and Phyto Lab (Vestenbergsgreuth, Germany) (See Supplementary data for further details). Ethanol for standard solutions and samples preparation was HPLC grade (J.T. Baker, Phillipsburg, NJ, USA). All terpene standards are Certified Reference Materials (CRM) standards, at 2500 µg/mL in isopropanol.