Primary tumors were represented in tissue microarrays (TMAs) compiled by the Tumor Bank. To construct a TMA, all cases were initially selected from the database and then sections were re-reviewed to confirm and select areas for coring of corresponding blocks. Duplicate tissue cores (0.6 mm diameter) were taken from central cellular areas of each tumor with a tissue arrayer instrument (Beecher Instruments, Silver Spring, MD, USA). The original cohort of 636 cases was arrayed across 7 blocks. Prior utilization of these blocks and exhaustion of individual cores meant that the final interpretable cohort for this study was 443 cases.
Tissue arrayer instrument
Manufactured by Beecher Instruments
Sourced in United States
The tissue arrayer instrument is a device used to create tissue microarrays (TMAs) for research purposes. It precisely arranges and transfers small tissue samples from donor blocks onto a recipient paraffin block, enabling the simultaneous analysis of multiple tissue samples on a single slide.
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Lab products found in correlation
2 protocols using tissue arrayer instrument
1
Tissue Microarray Construction for Cancer Research
2
Tissue Microarray Construction Protocol
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Primary tumors were represented in tissue microarrays (TMAs) compiled by the Tumor Bank. To construct a TMA, all cases were initially selected from the database and then sections were re-reviewed to confirm and select areas for coring of corresponding blocks. Duplicate tissue cores (0.6 mm diameter) were taken from central cellular areas of each tumor with a tissue arrayer instrument (Beecher Instruments, Silver Spring, MD, USA).
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