High sensitivity assay

Manufactured by Siemens

The High-sensitivity assay is a lab equipment product designed to perform highly sensitive and accurate measurements. It is capable of detecting and quantifying target analytes at very low concentrations. The core function of this product is to provide researchers and scientists with a reliable tool for conducting precise and sensitive analyses in various applications.

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Lab products found in correlation

Close spelling variants of this product

Atellica IM High Sensitivity Troponin I assay (4 citations)

3 protocols using high sensitivity assay

Cardiometabolic Biomarkers in HIV

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Interviews and structured questionnaires were given to all participants at the time of enrollment covering sociodemographic characteristics, CVD risk factors, HIV disease history, medications, and health-related behaviors, including drug use. Fasting blood work was drawn to measure serum total cholesterol, triglycerides, and high-density lipoprotein (HDL) cholesterol. Low-density lipoprotein (LDL) cholesterol was calculated using Friedewald formula^{6 (link)} except for participants with triglycerides ≥400 or <40 mg/dL, where it was measured directly. High-sensitivity C-reactive protein levels were measured using a high-sensitivity assay (Dade Behring, Deerfield, IL).

Phan B.A., Weigel B., Ma Y., Scherzer R., Li D., Hur S., Kalapus S.C., Deeks S, & Hsue P. (2017). Utility of 2013 American College of Cardiology/American Heart Association Cholesterol Guidelines in HIV-Infected Adults With Carotid Atherosclerosis. Circulation. Cardiovascular Imaging, 10(7), e005995.

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Comprehensive Cardiovascular Health Evaluation

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Interviews and structured questionnaires were given to all participants at the time of enrollment covering socio-demographic characteristics, CVD risk factors, HIV disease history, medications, and health-related behaviors including drug use. Fasting blood work was drawn to measure serum total cholesterol, triglycerides (TG), and high-density lipoprotein cholesterol (HDL-C). Low-density lipoprotein cholesterol (LDL-C) was calculated using Friedewald’s formula except for participants with TG ≥ 400 mg/dL or < 40 mg/dL, where it was measured directly [10 (link)]. High-sensitivity C-reactive protein (hs-CRP) levels were measured using a high-sensitivity assay (Dade Behring, Deerfield, IL).

Phan B.A., Ma Y., Scherzer R., Deeks S.G, & Hsue P.Y. (2020). Association between statin use, atherosclerosis, and mortality in HIV-infected adults. PLoS ONE, 15(4), e0232636.

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Measuring Inflammatory Biomarkers in Plasma

Cited 1 time

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Circulating levels of inflammatory biomarkers were measured from prospectively collected plasma stored in the laboratory of Dr. Nader Rifai (Boston, MA). CRP levels were measured using a high-sensitivity assay (Dade Behring). IL-6 and TNFR2 levels were determined by a commercially available enzyme-linked immunosorbent assay test (R and D Systems)(20 (link)). The median coefficients of variation (CV) for CRP, IL-6 and TNFR2 were 0.5%, 5.3%, and 6.8%, respectively(9 (link),20 (link)). All laboratory personnel were blinded from case/control status. Case/control pairs were assayed in adjoining wells, and 10% of samples were randomly distributed across the plates as pooled quality controls.

Markt S.C., Rider J.R., Penney K.L., Schumacher F.R., Epstein M.M., Fall K., Sesso H.D., Stampfer M.J, & Mucci L.A. (2014). Genetic Variation across C-Reactive Protein and Risk of Prostate Cancer. The Prostate, 74(10), 1034-1042.

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