3t whole body scanner

Manufactured by GE Healthcare

Sourced in United States

The 3T whole body scanner is a magnetic resonance imaging (MRI) system that generates high-resolution images of the human body. It operates at a magnetic field strength of 3 tesla, allowing for improved image quality and faster scanning times compared to lower-field MRI systems. The 3T whole body scanner is designed to capture detailed anatomical information across the entire body.

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Lab products found in correlation

8 channel head coil, by GE Healthcare (1 mentions)

Close spelling variants of this product

3T scanner (86 citations) Signa 3T whole-body scanner (7 citations) 3T whole-body MRI scanner (3 citations) Scanners (2 citations) 3T MR750 whole-body 60 cm bore MRI scanner (2 citations)

6 protocols using 3t whole body scanner

Quantifying Liver Fat Fraction via MRS

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MRS was performed on a 1.5 Tesla (T) whole body clinical scanner (General Electric Healthcare, Waukesha, WI) from December 2003 to February 2010 and on a 3T whole body scanner (General Electric Healthcare, Waukesha, WI) beginning in March 2010. Data collected from the 1.5T scanner were standardized to values collected from the 3T scanner. All VAHH participants were scanned using the same 3T scanner as used in WIHS participants. A time series of 128 (1.5T) or 64 (3T) acquisitions of spectra were obtained from an 8 cubic centimeter (cm³), single voxel region of tissue and were analyzed with motion correction and T2 relaxation time correction algorithms using a standardized MRS protocol[28 (link)]. The peak areas under the resonance frequencies of lipids and unsuppressed water were calculated for each participant and the liver fat fraction (LFF) derived as the ratio of the total lipids measure to the total lipids plus unsuppressed water measure. The LFF was then multiplied by 100 and expressed as a percent. A mean inter-examination coefficient of variation for MRS-measured LFF of 11.9% (range 2.8 – 20.3%) in a sample of 9 controls confirmed its reproducibility. Steatosis was defined as a LFF≥5%.

KARDASHIAN A., MA Y., SCHERZER R., PRICE J.C., SARKAR M., KORN N., TILLINGHAST K., PETERS M.G., NOWOROLSKI S.M, & TIEN P.C. (2017). Sex differences in the Association of HIV infection with Hepatic Steatosis. AIDS (London, England), 31(3), 365-373.

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PET Imaging of Ketamine's Effects

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For PET imaging, 40 patients will be randomly selected from the daytime and nighttime ketamine administration groups (20 per group) to undergo PET scans using the ¹¹C‐UCB‐J PET ligand at baseline and upon completion of the 24‐week treatment period. This subset of patients will be included in consideration of the difficulties involved in brain PET, including poor patient compliance and high cost (Rausch et al., 2017; Thompson et al., 2016). In brief, PET imaging will be performed using a high‐resolution research tomography (GE Health Care) with a reconstructed image resolution of nearly 3 mm, as described previously (Finnema et al., 2018; Nabulsi et al., 2016). These patients will also undergo T1‐weighted MRI imaging in a 3‐T whole‐body scanner (GE HealthCare) at the same timepoints for coregistration with the PET images.

Zhuo C., Tian H., Li G., Chen M., Jiang D., Lin X., Xu Y, & Wang W. (2019). Effects of ketamine on circadian rhythm and synaptic homeostasis in patients with treatment‐resistant depression: A protocol for mechanistic studies of its rapid and sustained antidepressant actions in humans. Brain and Behavior, 9(11), e01423.

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High-Resolution Diffusion Imaging Protocol

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Images were acquired on a 3T whole body scanner (General Electric Medical Systems) at Brigham and Women’s Hospital, Boston, MA. Diffusion weighted images were acquired with a high-spatial resolution twice refocused echo-planar imaging sequence (TR = 17 s, TE = 78 ms, flip angle 90°, FOV 240 × 240 mm, 85 slices, 1.7 × 1.7 mm in-plane, 1.7 mm slice thickness, 51 gradient directions with b = 900 s/mm 2, and 8 baseline scans with b = 0).
Diffusion weighted images were then corrected for head motion and eddy current distortion by performing an affine registration of each gradient weighted image to the baseline using Brain Extraction Tool (BET) software (Smith 2002 (link)).

Hamoda H.M., Makhlouf A.T., Fitzsimmons J., Rathi Y., Makris N., Mesholam-Gately R.I., Wojcik J.D., Goldstein J., McCarley R.W., Seidman L.J., Kubicki M, & Shenton M.E. (2019). Abnormalities in thalamo-cortical connections in patients with first-episode schizophrenia: a two-tensor tractography study. Brain imaging and behavior, 13(2), 472-481.

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In Vivo Liver MRI/MRE Evaluation in Mice

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The MRI/MRE scans were performed using a 3T whole-body scanner (GE Healthcare) [22 (link)]. Briefly, after preparation and administration of maintenance anesthesia with isoflurane, each mouse was placed in a plastic cradle in the supine position, then slid into a custom 8-channel birdcage imaging coil. A disposable silver acupuncture needle with a 0.26-mm diameter and 39-mm length (Asahi Medical Instrument) was inserted into the liver through the anterior body wall. The other end of the needle was connected to a passive pneumatic driver that generated longitudinally oriented sinusoidal vibrations at 80-Hz. MRE phase (“wave”) images were acquired with a free-breathing, spin-echo echo-planar-imaging MRE sequence. Hepatic FF (%) was measured using a two-point Dixon method [23 (link)]. Details of imaging protocols are given in Appendix-E1.

Yin Z., Murphy M.C., Li J., Glaser K.J., Mauer A.S., Mounajjed T., Therneau T.M., Liu H., Malhi H., Manduca A., Ehman R.L, & Yin M. (2019). Prediction of Nonalcoholic Fatty Liver Disease (NAFLD) Activity Score (NAS) with Multiparametric Hepatic Magnetic Resonance Imaging and Elastography. European radiology, 29(11), 5823-5831.

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Resting-state fMRI and Structural Brain Imaging

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All MRI scans were acquired using a GE 3T whole-body scanner (GE, Waukesha, Wisconsin, USA) with a standard transmit-receive quadrature head coil. These included an 8-min task free R-fcMRI scan using a single-shot gradient echo-echo planar (EPI) imaging and a 6-min high-resolution three-dimensional spoiled gradient-recalled echo (SPGR) pulse sequences. All participants were instructed to close their eyes and relax during the scans. The R-fcMRI imaging parameters were: TE = 25 ms, TR = 2000 ms, flip angle (FA) = 90°, number of slices = 36, slice thickness = 4 mm, matrix size = 64 × 64, and field of view (FOV) = 240 × 240 mm. The SPGR axial images were acquired for anatomical reference with parameters: TE = 3.2 ms, TR = 8.2 ms, TI = 450 ms, FA = 12°, number of slices = 150, slice thickness = 1 mm, matrix size = 256 × 192, and FOV = 240 × 240 mm².

Li W., Ward B.D., Xie C., Jones J.L., Antuono P.G., Li S.J, & Goveas J.S. (2015). Amygdala Network Dysfunction in Late-Life Depression Phenotypes: Relationships with Symptom Dimensions. Journal of psychiatric research, 70, 121-129.

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Structural Brain Imaging Protocol for Neurofeedback

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Participants in the NF group underwent structural brain scanning in a 3 T whole body scanner (General Electric, Milwaukee, USA) with an 8-channel head coil. The parameters used for the acquisition of a high-resolution anatomical scan (Fast Spoiled Gradient-Recalled-Echo [FSPGR] sequence) were: 178 slices, TE=3 ms, TR=7.9 ms, voxel size=1.0×1.0×1.0 mm³, FA=15°, FOV=256×256. The structural scan was used for coregistration and anatomical localisation of the functional data obtained from the real-time fMRI neurofeedback data acquisition.

Habes I., Rushton S., Johnston S.J., Sokunbi M.O., Barawi K., Brosnan M., Daly T., Ihssen N, & Linden D.E. (2016). fMRI neurofeedback of higher visual areas and perceptual biases. Neuropsychologia, 85, 208-215.

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