Corescan software

Manufactured by GE Healthcare

Sourced in United States

CoreScan is a software solution developed by GE Healthcare to assist healthcare professionals in the analysis and interpretation of medical imaging data. The core function of CoreScan is to provide automated tools for image segmentation, quantification, and visualization to support clinical decision-making.

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Lab products found in correlation

Ge lunar idxa, by GE Healthcare (1 mentions) Fibroscan 502 touch, by Echosens (1 mentions) Lunar prodigy, by GE Healthcare (1 mentions) Quark, by Cosmed (1 mentions) Lunar idxa, by GE Healthcare (1 mentions) Dxa lunar prodigy primo, by GE Healthcare (1 mentions)

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CoreScan (27 citations)

5 protocols using corescan software

Quantifying Body Composition with DXA Scan

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The DXA scan was conducted on a GE Lunar iDXA (GE Healthcare, Software Lunar DPX enCORE 2012 version 14.0, Madison, WI, USA). Each participant received a total body scan, conducted by a single qualified radiographer (AE) who was experienced in DXA scanning. Participants were scanned in the supine position and VAT was estimated using the android region (from the ribs to the iliac crest) via the inbuilt CoreScan software (GE Healthcare, Software Lunar DPX enCORE 2012 version 14.0, Madison, WI, USA). FFM was determined by the sum of bone mineral content and lean soft tissue values, and FM was also determined. The coefficient of the variations were 0.74% for FM, 0.48% for lean mass, and 11.84% for VAT volume.

Day K., Kwok A., Evans A., Mata F., Verdejo-Garcia A., Hart K., Ward L.C, & Truby H. (2018). Comparison of a Bioelectrical Impedance Device against the Reference Method Dual Energy X-Ray Absorptiometry and Anthropometry for the Evaluation of Body Composition in Adults. Nutrients, 10(10), 1469.

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Body Composition Analysis via DXA Scan

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DXA scan variables will include total mass, total lean mass, tissue % lean, and tissue % fat. Scans will be analyzed using CoreScan software (GE HealthCare).

Lai B., Oster R.A., Davis D., Bright L., Fisher G., Wilroy J., Kim Y., Young R., Wright A., Sinha T, & Rimmer J.H. (2024). Telehealth Movement-to-Music With Arm-Based Sprint-Intensity Interval Training to Improve Cardiometabolic Health and Cardiorespiratory Fitness in Children With Cerebral Palsy: Protocol for a Pilot Randomized Controlled Trial. JMIR Research Protocols, 13, e56499.

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Comprehensive Metabolic Profiling of Participants

Cited 1 time

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The baseline visit is performed approximately 4–6 weeks after the screening/enrolment visit (table 1). Participants attend the Clinical Research Facility following an overnight fast. Blood is drawn for serum lipids measurement and anthropometric measures and blood pressure are taken. Arterial stiffness (pulse wave analysis, AtCor Medical, Australia) is measured twice and average recorded, as described.22 (link) This is followed by measurement of resting energy expenditure, carbohydrate and fat oxidation over 30 min by indirect calorimetry (Quark, Cosmed, Italy).23 (link) Body composition is assessed using dual-energy X-ray absorptiometry (DXA, Lunar Prodigy, GE Healthcare). Specifically, total body fat mass and fat-free mass (enCORE software), the android and gynoid region, and visceral fat (CoreScan software, GE Healthcare) are recorded.24 (link) Liver steatosis (controlled attenuation parameter, CAP) and liver fibrosis (liver stiffness measurements, LSMs) are assessed using FibroScan (Touch 502 by Echosens) by a trained technician. CAP and LSMs have been reported to correlate closely with steatosis and fibrosis assessed using the gold standard liver biopsy.25 (link) A physical activity monitor (ActivePal, Pal Technologies) is applied on the thigh for a period of 14 days. At the end of the baseline visit, the participants practice using the app with the dietician.

Htet T.D., Godneva A., Liu Z., Chalmers E., Kolobkov D., Snaith J.R., Richens R., Toth K., Danta M., Hng T.M., Elinav E., Segal E., Greenfield J.R, & Samocha-Bonet D. (2020). Rationale and design of a randomised controlled trial testing the effect of personalised diet in individuals with pre-diabetes or type 2 diabetes mellitus treated with metformin. BMJ Open, 10(10), e037859.

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Comprehensive Body Composition Assessment

Cited 1 time

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Body composition components (fat, lean, and bone mass) were measured with a third-generation DXA scanner (DXA Lunar Prodigy Primo and Lunar iDXA; GE Healthcare) connected with enCore software by trained operators at baseline, 1-year, and 3-year follow-up. Operational definition of regions of interest for body composition measured with DXA is available in the eMethods in Supplement 2.
For visceral fat measurements in an android region, DXA scans were reanalyzed using CoreScan software application (GE Healthcare) validated using computed tomographic scans as a reference tool.^{17 (link)} The primary end points were lean and fat mass expressed as the percentage of DXA-derived total body mass (sum of total bone, fat, and lean mass), to better capture changes in body composition proportions during weight loss, and visceral fat mass expressed in grams, given that it is the most usual measure for this body fat compartment. To deepen our understanding of body composition changes, other secondary outcomes were also examined: overall lean and fat mass expressed in absolute amounts (grams), and visceral fat expressed as the percentage of total fat mass. Furthermore, the ratio of android to gynoid fat was calculated to account for age-related adiposity redistribution from central to peripheral regions, as well as the ratio of lean mass to fat mass as a marker of sarcopenic obesity.

Konieczna J., Ruiz-Canela M., Galmes-Panades A.M., Abete I., Babio N., Fiol M., Martín-Sánchez V., Estruch R., Vidal J., Buil-Cosiales P., García-Gavilán J.F., Moñino M., Marcos-Delgado A., Casas R., Olbeyra R., Fitó M., Hu F.B., Martínez-Gonzalez M.Á., Martínez J.A., Romaguera D, & Salas-Salvadó J. (2023). An Energy-Reduced Mediterranean Diet, Physical Activity, and Body Composition: An Interim Subgroup Analysis of the PREDIMED-Plus Randomized Clinical Trial. JAMA Network Open, 6(10), e2337994.

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Comprehensive Body Composition Assessment

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Height is measured to the nearest 0.1 cm and weight measured to the nearest 0.01 kg to compute Body Mass Index (BMI). Waist and hip circumference are measured to the nearest 0.1 cm to compute waist to hip ratio. Percentage body fat, Total Mass (Kg), Fat Body Mass (g), Lean Body Mass (g) Bone Mineral Content (g) and Fat Free Mass (g) are measured using a dual-energy x-ray absorptiometry (Lunar model iDXA; Core Scan Software, GE Healthcare, Madison, WI). Scans are completed with subjects placed in a supine position with arms and legs close to their body for a whole body scan following a standardized protocol (Lunar Corp., Model DPX-L, Madison, WI). All scans and QC measures are performed by the same technologist on the same equipment in the same location in a semi-automatic manner according to standardized procedures.

Owusu C., Nock N.L., Hergenroeder P., Austin K., Bennet E., Cerne S., Moore H., Petkac J., Schluchter M., Schmitz K.H., Webb-Hooper M., Atkins L., Asagba O., Wimbley L, & Berger N.A. (2020). IMPROVE, a Community-based Exercise Intervention versus Support Group to Improve Functional and Health Outcomes among Older African American and Non-Hispanic White Breast Cancer Survivors from Diverse Socioeconomic Backgrounds: Rationale, Design and Methods. Contemporary clinical trials, 92, 106001.

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