Neuroimaging data were collected on a Siemens Avanto 1.5 T MRI scanner using a 32-channel head coil. To correct for inhomogeneities of the static magnetic field, fieldmaps were acquired and used in the unwarping stage of data preprocessing. Four functional scanning sessions, composed of 4 dummy and 203 functional volumes, were acquired using a pre-scan normalized gradient echo-planar imaging sequence with the following parameters: volume repetition time = 3.132 s, echo time = 50 ms, flip angle = 90°, matrix = 64 × 64, voxel size = 3 × 3 × 3 mm3, 36 axial slices sampled for whole-brain coverage, tilt = −30°. A T1-weighted magnetization-prepared rapid gradient-echo (MP-RAGE) anatomical scan was acquired at the end of the session (176 sagittal slices, repetition time = 2.73 s, echo time = 3.57 ms, flip angle = 7°, matrix = 224 × 256, voxel size = 1 × 1 × 1 mm3).
Avanto 1.5t mri scanner
Manufactured by Siemens
Sourced in Germany
The Avanto 1.5T MRI scanner is a magnetic resonance imaging device produced by Siemens. It uses a 1.5 tesla superconducting magnet to generate high-quality images of the human body for medical diagnostic purposes.
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24 protocols using avanto 1.5t mri scanner
1
Neuroimaging Protocol for Brain Function
2
Multimodal Neuroimaging Protocol for Brain Imaging
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Structural and functional measures were obtained with a Siemens Avanto 1.5 T MRI scanner and 30-channel coil (a customized 32 channel coil without obstructed view). BOLD measures were acquired using four single-shot EPI runs (TR = 2.5 s, volumes = 144, slices = 30 voxel size = 3.2 × 3.2 x 3.2 mm, axial plane, ascending, bandwidth = 1930 Hz/pix, TE = 39 ms, flip = 90). The high-resolution structural scan was acquired using a T1-weighted 3D MPRAGE (1 mm3 voxel size, Bandwidth = 190 Hz/pix, 176 partitions, partition TR = 2730, TR = 8.4 ms, TE = 3.57, effective TI = 1000 ms, flip angle = 7 °).
3
Multimodal Brain Imaging Protocol
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MR imaging was performed on a Siemens Avanto 1.5 T MRI scanner, using a 12 channel phased array head coil. The MR imaging protocol consisted of a whole brain T1-weighted structural MRI scan and a DTI acquisition. The T1-weighted volume images were acquired using a magnetisation-prepared rapid gradient echo (MPRAGE) sequence with the following parameters: TR/TE/TI = 2400/3.42/1000 ms, flip angle = 80, voxel size = 1.2 mm × 1.2 mm × 1.2 mm, 160 slices (acquired in a sagittal plane), acquisition time = 7 min 42 s.
The DTI (single shot echo planar imaging) sequence parameters were as follows: TR/TE = 8900/109 ms, 63 non-collinear diffusion directions (including 3 interleaved b = 0 acquisitions), voxel size = 2.3 mm × 2.3 mm × 2.3 mm, b-value = 1000 s/mm2, parallel imaging factor = 2, 60 slices (acquired in an oblique axial plane avoiding the orbits where possible), acquisition time = 10 min 7 s. The T1-weighted volume images were clinically reported for any structural abnormalities by an experienced pediatric neuroradiologist.
The DTI (single shot echo planar imaging) sequence parameters were as follows: TR/TE = 8900/109 ms, 63 non-collinear diffusion directions (including 3 interleaved b = 0 acquisitions), voxel size = 2.3 mm × 2.3 mm × 2.3 mm, b-value = 1000 s/mm2, parallel imaging factor = 2, 60 slices (acquired in an oblique axial plane avoiding the orbits where possible), acquisition time = 10 min 7 s. The T1-weighted volume images were clinically reported for any structural abnormalities by an experienced pediatric neuroradiologist.
4
Functional MRI Acquisition Protocol
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Images were acquired using a Siemens Avanto 1.5-T MRI scanner. These included a 5.5-minute T1 weighted structural scan, and 184 multislice T2-weighted echo planar volumes with blood oxygenation level-dependent contrast, taken during 1 9-minute run of the cartoon task. Acquisition parameters were: 35 2 mm slices with a 1 mm gap; echo-time = 50 milliseconds; repetition time = 2975 milliseconds; slice tilt = −30 (T > C): flip angle = 90o; field of view = 192 mm; matrix size = 64 × 64. Fieldmaps were also obtained and used to adjust functional scans for deformations due to magnetic field in-homogeneities during pre-processing.
5
ADNI Longitudinal MRI Biomarkers
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In addition to the longitudinal LCBC datasets, we also include scans from the Alzheimer’s disease Neuroimaging Initiative (ADNI) database (adni.loni.usc.edu ). The ADNI was launched in 2003 as a public-private partnership, led by Principal Investigator Michael W. Weiner, MD. The primary goal of ADNI has been to test whether serial MRI, positron emission tomography, other biological makers, and clinical and neuropsychological assessment can be combined to measure the progression of MCI and early AD. For up-to-date information, see www.adni-info.org . For our study, we randomly select three groups of participants with similar age distributions: CN, MCI and AD. Each group consist of 20 participants. The selected sample of ADNI data has been acquired at different sites using a Siemens Avanto 1.5T MRI scanner and MPRAGE sequence: TR = 2400 ms, TE = 3.54 ms, TI = 1000 ms, flip angle = 8°, voxel size = 1.25 × 1.25 × 1.2 mm3, 192 × 192 acquisition matrix, 160 slices, 180 Hz pixel bandwidth, GRAPPA = 1, 8 channel matrix coil. Each participant has two visits with a follow-up ranging from 6 months to 2 years for each group.
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ADNI Longitudinal MRI Biomarkers
7
High-Resolution Functional Neuroimaging
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A Siemens Avanto 1.5T MRI scanner with a 32-channel head coil was used to acquire a 5.5 min 3D T1-weighted structural scan, and two runs of 199 multislice T2*-weighted echo planar volumes with BOLD contrast (∼10 min per run). The EPI sequence was designed to optimize signal detection and reduce dropout in OFC and amygdala (Weiskopf et al., 2006 (link)), and used the following acquisition parameters: 35 2mm slices acquired in an ascending trajectory with a 1 mm gap, TE = 50 ms; TR = 2975 ms; slice tilt = −30° (T > C); flip angle = 90°; field of view = 192 mm; matrix size = 64×64.
8
Cerebral Microbleeds Evaluation Protocol
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All patients were evaluated by MRI performed using a Siemens Avanto 1.5 T MRI scanner. The protocol performed included volumetric T1-weighted 3D MPR (FoV: 256 mm, slice thickness: 1 mm, TR: 1600 ms, TE: 3.01 ms, and distance factor: 50%); T2 TSE axial (FoV: 230 mm, slice thickness: 5 mm, TR: 3560 ms, TE: 89 ms, and distance factor: 30%); FLAIR axial (FoV: 230 mm, slice thickness: 5 mm, TR: 8000 ms, TE: 94 ms, and distance factor: 30%); T2 gradient echo axial (FoV: 230 mm, slice thickness: 5 mm, TR: 800 ms, TE: 26 ms, and distance factor: 30%); echo planar diffusion images (FoV: 230 mm, slice thickness: 5 mm, TR: 3902 ms, TE: 102 ms, and distance factor: 40%); T2 TSE coronal (FoV: 210 mm, slice thickness: 5 mm, TR: 3250 ms, TE: 100 ms, and distance factor: 20%).
The presence and number of CMBs was evaluated manually by two independent reviewers on axial SWI images according to current consensus criteria [24 (link)] and categorized as lobar (i.e., cortical-subcortical), deep (i.e., basal ganglia, thalamus or brainstem), or mixed (any lobar). The total number of CMBs was also recorded.
The presence and number of CMBs was evaluated manually by two independent reviewers on axial SWI images according to current consensus criteria [24 (link)] and categorized as lobar (i.e., cortical-subcortical), deep (i.e., basal ganglia, thalamus or brainstem), or mixed (any lobar). The total number of CMBs was also recorded.
9
Prostate Brachytherapy Imaging Protocol
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Four weeks after prostate brachytherapy, CT and MRI data were acquired for dosimetric analysis according to the recommended schedule [14 (link)]. Three imaging sequences were obtained: fat-suppressed T1-weighted imaging (FST1-WI), T2-weighted imaging (T2-WI), and T2*-weighted imaging (T2*-WI) using a Siemens Avanto 1.5T MRI scanner (Siemens, Munich, Germany) with 3 mm-thick-slices. The technical parameters of FST1-WI were as follows: repetition time (TR)/echo time (TE) in ms, 955/150; in-plane resolution, 1.0 × 0.7 mm2. The technical parameters of T2-WI were: TR/TE, 5000/100; in-plane resolution, 1.0 × 0.7 mm2; Turbo Spin Echo factor, 15. The technical parameters of T2*-WI were: TR/TE, 600/19; in-plane resolution, 1.1 × 0.7 mm2. FST1-WI, T2-WI, and T2*-WI were obtained successively. During PID, the prostate is contoured using T2-WI to estimate prostate volume.
Within 1 h of MRI, a post-implant CT was performed using a GE spiral CT (Hi-Speed Dxi; GE Healthcare, Buckinghamshire, UK). During the CT scan, a urinary catheter (8 Fr) was inserted. Sequences of 2 mm slices were acquired using a 50 mm field of view (FOV), and a pitch of 2 mm/2 mm = 1 (defined as the table feed/total detector width of the collimated beam). No intravenous contrast material was used during the CT or MRI scans.
Within 1 h of MRI, a post-implant CT was performed using a GE spiral CT (Hi-Speed Dxi; GE Healthcare, Buckinghamshire, UK). During the CT scan, a urinary catheter (8 Fr) was inserted. Sequences of 2 mm slices were acquired using a 50 mm field of view (FOV), and a pitch of 2 mm/2 mm = 1 (defined as the table feed/total detector width of the collimated beam). No intravenous contrast material was used during the CT or MRI scans.
10
High-Resolution Neuroimaging Protocol
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