Male nmri mice

Manufactured by Taconic Biosciences

Sourced in Denmark

Male NMRI mice are an outbred mouse strain commonly used in research. They are nocturnal, possess a white or cream colored coat, and have a lifespan of approximately 1-2 years. These mice are suitable for a variety of research applications.

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Lab products found in correlation

Sprague dawley rats, by Taconic Biosciences (1 mentions) C57bl 6 mice, by Jackson ImmunoResearch (1 mentions) Nmri mice, by Taconic Biosciences (1 mentions)

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NMRI mice (20 citations)

2 protocols using male nmri mice

Rodent Models for Neuroscience Research

Cited 1 time

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Male NMRI mice (Taconic, Lille Skensved, Denmark) were used for microdialysis and c-fos experiments.^{4 (link)} Sprague Dawley rats, weighing 320–345 g, were also used for the study (Taconic). All other in vivo experiments used adult male C57BL/6 mice from Jackson Laboratories or bred internally at the Vanderbilt University. All the animals were kept at room temperature in a 12 h light/dark cycle with free access to food and water. All the experiments were performed during the light cycle. For immunohistochemical characterization of GLP-1R localization, bacterial artificial chromosome transgenic mice containing a fluorescent reporter expressed in GLP-1R-expressing cells were generated as described in Supplementary Information. All the experiments were in accordance with directives of ‘Principles of Laboratory Animal Care' (NIH publication No. 85–23) and approved by either the Danish Experimental Animal Inspectorate and the council of the European Communities or the Vanderbilt Institutional Animal Care and Use Committee.

Reddy I.A., Pino J.A., Weikop P., Osses N., Sørensen G., Bering T., Valle C., Bluett R.J., Erreger K., Wortwein G., Reyes J.G., Graham D., Stanwood G.D., Hackett T.A., Patel S., Fink-Jensen A., Torres G.E, & Galli A. (2016). Glucagon-like peptide 1 receptor activation regulates cocaine actions and dopamine homeostasis in the lateral septum by decreasing arachidonic acid levels. Translational Psychiatry, 6(5), e809-.

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Behavioral Characterization of Mice

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Male NMRI mice (Taconic, Denmark) that weighed 28-35g were used for microdialysis and locomotor activity experiments, Male NMRI mice that weighed 20-22g were used for the acute self-administration experiment and male C57Bl/6 weighing 20-24g were used for chronic self-administration experiments. All mice were housed in Makrolon cages (20 × 35 × 15 cm) enriched with cardboard housing and nesting material. The animals were kept at room temperature (22°C ± 2) in a 12-hour light/dark cycle (lights on at 6:00 A.M.) with free access to food and water. All experiments were performed during the light cycle between 9:00 A.M. and 4:00 P.M. The mice were allowed to acclimatize to the animal facility for 6-9 days prior to initiation of the experiments. All experiments were approved by the Danish Experimental Animal Inspectorate and were in accordance with the directives of the “Principles of Laboratory Animal Care” (NIH publication No. 85-23, revised 1985) and the council of the European Communities (86/809/EEC).

Sørensen G., Reddy I.A., Weikop P., Graham D.L., Stanwood G.D., Wortwein G., Galli A, & Fink-Jensen A. (2015). The Glucagon-Like Peptide 1 (GLP-1) Receptor Agonist Exendin-4 Reduces Cocaine Self-Administration in Mice. Physiology & behavior, 149, 262-268.

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