Methamphetamine HCl (METH) was provided by the Research Pharmacy of the National Institute on Drug Abuse Intramural Research Program and dissolved in sterile 0.9% physiological saline. BCP was obtained from MilliporeSigma (Burlington, MA, United States) and dissolved in 5% Kolliphor EL (i.e., Cremophor) (BASF Pharma, Ludwigshafen, Germany). The BCP doses were chosen from our previous reports (Galaj and Xi, 2020 (link); He et al., 2020 (link)). AM630 was purchased from Tocris Division of Bio-Techne (Minneapolis, MN, United States) and dissolved in saline; the doses of AM630 (3, 10 mg/kg) were chosen based on our previous experiments (Galaj and Xi, 2020 (link)).
Kolliphor el
Manufactured by BASF
Sourced in Germany, United States, India
Kolliphor EL is a non-ionic surfactant used in various pharmaceutical and biomedical applications. It is a polyethoxylated castor oil derivative that functions as an emulsifier, solubilizer, and wetting agent. The core properties of Kolliphor EL include its ability to enhance the solubility and bioavailability of lipophilic drugs and its use in the formulation of drug delivery systems.
Automatically generated - may contain errors
Lab products found in correlation
Kolliphor hs 15, by BASF (8 mentions)
Kolliphor rh40, by BASF (7 mentions)
Tween 80, by Merck Group (5 mentions)
Capryol 90, by Gattefosse (5 mentions)
Tween 20, by Merck Group (4 mentions)
Labrasol, by Gattefosse (4 mentions)
Kollisolv mct 70, by BASF (4 mentions)
Kolliphor ps80, by BASF (4 mentions)
Transcutol p, by Gattefosse (4 mentions)
Oleic acid, by Merck Group (3 mentions)
Kolliphor p188, by BASF (3 mentions)
Methanol, by Avantor (2 mentions)
Acetic acid, by Merck Group (2 mentions)
Polyethylene glycol peg 400, by Merck Group (2 mentions)
Kollisolv peg 400, by BASF (2 mentions)
Kolliphor ps20, by BASF (2 mentions)
Lauroglycol 90, by Gattefosse (2 mentions)
Kollidon k90, by BASF (2 mentions)
Cremophor el, by BASF (2 mentions)
Aerosil 200, by Evonik (2 mentions)
33 protocols using kolliphor el
1
Methamphetamine and Cannabinoid Receptor Modulation
2
Oral Gavage Toxicity Assessment
3
Betamethasone Dipropionate SMEDDS Hydrogel
Check if the same lab product or an alternative is used in the 5 most similar protocols
+ Expand
Gel NCC ((gNCC) Navitas, Podcerkev, Slovenia), powder NCC ((pNCC) Celluforce, Montreal, QC, Canada), sodium alginate ((ALG) Protanal® LF 10/60, FMC BioPolymer, Philadelphia, PA, USA), pectin ((PEC) Sigma-Aldrich, St. Louis, MO, USA), glycerol (Pharmachem, Ljubljana, Slovenia), and purified water were used to prepare the film-forming hydrogels. Capryol® 90 (Gattefosse, Saint-Priest, France) and Kolliphor® EL (BASF, Ludwigshafen, Germany) were used to form a self-microemulsifying drug delivery system (SMEDDS). For the solubility study of betamethasone dipropionate ((BDP) Sicor S.R.L., Roveretto, Italy), oleic acid (Sigma-Aldrich, St. Louis, MO, USA), Plurol® Oleique (Gattefosse, Saint-Priest, France), isopropyl myristate (Sigma-Aldrich, USA), Tween 80 (Merck, Darmstadt, Germany), Tween 20 (Merck, Darmstadt, Germany), Labrasol (Gattefosse, Saint-Priest, France), and polyethylene glycol 400 (Sigma-Aldrich, St. Louis, MO, USA) were used as excipients. For HPLC (high-performance liquid chromatography) analysis, all reagents (acetic acid (Merck, Darmstadt, Germany), methanol (Avantor, Radnor, PA, USA), and acetonitrile (Avantor, Radnor, PA, USA)) were of HPLC grade.
4
Formulation of Lipid-Based Nanocarriers
Check if the same lab product or an alternative is used in the 5 most similar protocols
+ Expand
Dynasan 118 (tristearin) was obtained from IOI OLEO GmbH (Hamburg, Germany). Compritol 888 ATO and Gelucire®48/16 were kindly supplied from Gattefossè (Milan, Italy). Kolliphor® P188 (Poloxamer 188) and Kolliphor® EL, formerly known as Cremophor® EL (Polyoxyl 35 Hydrogenated Castor Oil), were a gift of BASF. Cetylstearyl alcohol, polyethylene glycol (PEG) 400, PEG 4000 and rhodamine B (Rho) were purchased from Sigma Aldrich (Steinheim, Germany). All other chemicals were of analytical grade. The properties of the hydrophobic and hydrophilic compounds are reported in Table 1 .
5
Formulation Development of Alectinib Hydrochloride
Check if the same lab product or an alternative is used in the 5 most similar protocols
+ Expand
Alectinib hydrochloride was purchased from Wuhan Vanz Pharm Inc. (Wuhan, China). Kolliphor HS 15 (polyoxyl 15 hydroxy stearate), Kollisolv PEG 300 (polyethylene glycol 300), Kollisolv PEG 400 (polyethylene glycol 400), Kolliphor EL (polyoxyl 35 castor oil), Kolliphor PS 20 (Polysorbate 20), Kolliphor PS 80 (polysorbate 80), Kolliphor RH 40 (polyoxyl 40 hydrogenated castor oil), and Kollisolv MCT 70 (medium-chain capric triglyceride) were kindly provided by BASF (Ludwigshafen, Germany). Transcutol P (diethylene glycol monoethyl ether) and Capryol 90 (propylene glycol monocaprylate (type II)) were kindly provided by Gattefosse (Saint-Priest, France). Capmul MCM C8 (mono/diglycerides of caprylic acid) and Capmul MCM C10 (mono/diglycerides of capric acid) were kindly provided by ABITEC Corporation (Janesville, WI, USA). Sodium lauryl sulfate (SLS) was kindly provided by DUKSAN Pure Chemical (Ansan, Korea). All other chemicals were of reagent grade and were thus used without further purification.
6
Optimization of MTK Formulation Using Various Excipients
Check if the same lab product or an alternative is used in the 5 most similar protocols
+ Expand
The sodium salt form of MTK was obtained from Kyongbo Pharm. (Asan, Chungnam, Korea). Polyvinylpyrrolidone K30 (PVP K30), Kollidon/vinylpyrrolidone-vinyl acetate (VA64) copolymer, Poloxamer-188, Poloxamer-407, Kolliphor RH40 (polyoxyl 40 hydrogenated castor oil), Kolliphor EL (polyoxyl castor oil), Kolliphor HS 15 (polyoxyl 15 hydroxystearate) were kindly provided by BASF Co. (Ludwigshafen, Germany). Hypromellose 2910 (HPMC 2910), and trifluoroacetic acid were purchased from Sigma Chemical Co. (St. Louis, MO, USA). Polysorbate 20 and polysorbate 80 were obtained from Masung & Co. Ltd. (Seoul, Korea). Pharma grade xanthan gum was purchased from Arthur Branwell Co. Ltd. (Essex, UK). Essex EssexLactic acid and sodium hydroxide standard solution (1 N) were acquired from Daejung chemical & metal Co. Ltd. (Gyeonggi-do, Korea). Sunset Yellow FCF (disodium 2-hydroxy-1-(4-sulfonatophenylazo)naphthalene-6-sulfonate) was obtained from Bolak Co. Ltd. (Gyeonggi-do, Korea). Acetonitrile (ACN) and methanol of HPLC (High-performance liquid chromatography) grade were provided by J.T. Baker (Phillipsburg, NJ, USA). All other reagents were analytical grade and were used without further purification.
7
Formulation of Lipid-Based Drugs
Check if the same lab product or an alternative is used in the 5 most similar protocols
+ Expand
PPD (purity >99.9%, Figure 1 ) was purchased from Chengdu Biopurify Phytochemicals, Ltd. (Chengdu, China). Kolliphor HS15 (polyoxyl 15 hydroxystearate), Kolliphor EL (polyoxyl castor oil), Kolliphor PS 80 (polysorbate 80), and Kollisolv MCT 70 (medium chain triglycerides) were provided by BASF (Ludwigshafen, Germany). Capmul MCM C8 (mono/diglycerides of caprylic acid) and Capryol 90 (propylene glycol monocaprylate (type II) were provided by Gattefosse (Saint-Priest, France). All other chemicals were of reagent grade and were used without further purification.
8
Formulation Development and Characterization of Lipid-Based Drug Delivery Systems
Check if the same lab product or an alternative is used in the 5 most similar protocols
+ Expand
VST was supplied by Daewon Pharm. Co. Ltd. (Seoul, Republic of Korea). Capryol™ 90, Lauroglycol™ 90, Labrasol®, and Transcutol® P were supplied by Gattefossé (Saint Priest, France). Capmul® MCM was supplied by Abitec Co. (Janesville, WI, USA). Cremophor® EL (Kolliphor® EL), polyvinylpyrrolidone K90 (PVP K90; Kollidon® K90), d-α-tocopheryl polyethylene glycol 1000 succinate (Vitamin E TPGS; Kolliphor® TPGS), poloxamer 407 (Pluronic® F-127; POL), and Soluplus® were supplied by BASF (Ludwigshafen, Germany). Hypromellose E2910 (hydroxypropyl methylcellulose, [HPMC]) was supplied by Shin-Etsu Chemical Co. (Tokyo, Japan). Olive oil, corn oil, Tween® 20, Tween 80, and tetraglycol were purchased from Sigma-Aldrich (St Louis, MO, USA). Polyethylene glycol and polyethylene glycol 6000 PEG 6000) were purchased from Duksan Pure Chemical Co. Ltd. (Ansan, South Korea), and high-performance liquid chromatography (HPLC)-grade acetonitrile and methanol were purchased from JT Baker (Phillipsburg, NJ, USA). All other chemicals used were of analytical grade.
9
Formulation and Characterization of Lipid-Based Nano-Carriers
Check if the same lab product or an alternative is used in the 5 most similar protocols
+ Expand
PZH was purchased from Hangzhou Royall Import and Export Co., Ltd. (Hangzhou, China). Kolliphor EL (polyoxyl 35 castor oil), Kolliphor HS15 (polyoxyl 15 hydroxystearate), Kolliphor RH40 (polyoxyl 40 hydrogenated castor oil), Kolliphor PS80 (polysorbate 80), Kollisolv PG (propylene glycol), Kollisolv MCT70 (medium-chain triglyceride), and Kollisolv PEG400 (polyethylene glycol 400) were provided by BASF (Ludwigshafen, Germany). Capmul MCM C8 (glyceryl monocaprylate) and Capmul MCM C10 (glyceryl monocaprate) were provided by ABITEC (Columbus, OH, USA). Castor oil was provided by DongYang Oil Chemical (Anseong, Korea). All other chemicals were of reagent grade and were used without further purification.
10
Formulation Development of RVP Tablets
Check if the same lab product or an alternative is used in the 5 most similar protocols
+ Expand
RVP powder (purity >99%) and Revanex® tablets containing 200 mg RVP were supplied by Yuhan (Seoul, Korea). Aerosil® 200 was supplied by Evonik Degussa GmbH (Frankfurt am Main, Germany). Avicel PH 101, Brij L4 (BL4), Tween® 20, and Tween® 80 were purchased from Sigma-Aldrich (St. Louis, MO, USA). Florite PS-10 (FLO; calcium silicate) was purchased from Tomita Pharmaceutical Co., Ltd. (Tokushima, Japan). Gelucire 44/14 (G44), Labrafil® M 1944 CS, Labrasol®, and Lauroglycol® 90 were gifted by Gattefossé (Saint Priest, France). Kolliphor® EL, Kolliphor® RH40, Kolliphor® RH60, Kollidon K30, Kollidon K90, Poloxamer (P)188, and P407 were obtained from BASF (Ludwigshafen, Germany). Low-substituted hydroxypropyl cellulose B1 (L-HPC) was supplied by Shin-Etsu Chemical Co., Ltd. (Tokyo, Japan). Neusilin® US2 (magnesium aluminometasilicate) was supplied by Fuji Chemical Industry Company (Toyama, Japan). Sylysia® 350 (porous silica) was supplied by Fuji Silysia Chemical Co., Ltd. (Aichi, Japan). Vivapur (VP)12 and VP105 were supplied by JRS Pharma (Rosenberg, Germany). High-performance liquid chromatography (HPLC)-grade methanol was purchased from JT Baker (Phillipsburg, NJ, USA). All other chemicals used were of analytical grade.
About PubCompare
Our mission is to provide scientists with the largest repository of trustworthy protocols and intelligent analytical tools, thereby offering them extensive information to design robust protocols aimed at minimizing the risk of failures.
We believe that the most crucial aspect is to grant scientists access to a wide range of reliable sources and new useful tools that surpass human capabilities.
However, we trust in allowing scientists to determine how to construct their own protocols based on this information, as they are the experts in their field.
Ready to get started?
Sign up for free.
Registration takes 20 seconds.
Available from any computer
No download required
Revolutionizing how scientists
search and build protocols!