2 3 dimethylmaleic anhydride

Manufactured by Merck Group

Sourced in United States

2,3-dimethylmaleic anhydride is a chemical compound used as a precursor in various synthetic processes. It has the chemical formula C6H6O3. The product is a colorless, crystalline solid with a melting point of approximately 88°C.

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Lab products found in correlation

4 protocols using 2 3 dimethylmaleic anhydride

Chitin-based Nanomaterials for Bioimaging and Therapy

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The α-chitin powder from shrimp shells, sodium hydroxide (NaOH), dopamine hydrochloride, 2,3-dimethylmaleic anhydride, N, N′-dimethylformamide (DMF), trimethylamine (TEA), pyridine, anhydrous diethyl ether, gold (III) chloride hydrate (HAuCl₄), sodium citrate, N-(3-dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride (EDC), sodium tetraborate, bovine serum albumin (BSA), 9,10-dimethylanthracene, formaldehyde, and 4′,6-diamidino-2-phenylindole dihydrochloride (DAPI) were purchased from Sigma-Aldrich (St. Louis, MO, USA). Hydrochloric acid (HCl) was bought from Daejung (Seoul, Korea). Ce6 was acquired from Frontier Scientific Inc. (Logan, UT, USA). The BCA protein assay kit was bought from Thermo Fisher Scientific Inc. (Walthan, MA, USA). Dulbecco’s modified Eagle’s medium (DMEM), Roswell Park Memorial Institute (RPMI) 1640 medium, phosphate-buffered saline (PBS), ethylenediaminetetraacetic acid (EDTA), fetal bovine serum (FBS), penicillin, and streptomycin were purchased from Welgene Inc. (Seoul, Korea). Wheat Germ Agglutinin-Alexa Fluor^® 488 conjugate (WGA-Alexa Fluor^® 488) was purchased from Life Technologies (Carlsbad, CA, USA). The Cell Counting Kit-8 (CCK-8) was obtained from Dojindo Molecular Technologies Inc. (Santa Clara, CA, USA). FITC annexin V apoptosis detection kit I was acquired from BD Pharmingen (San Diego, CA, USA).

Yu H.S., Park H., Tran T.H., Hwang S.Y., Na K., Lee E.S., Oh K.T., Oh D.X, & Park J. (2019). Poisonous Caterpillar-Inspired Chitosan Nanofiber Enabling Dual Photothermal and Photodynamic Tumor Ablation. Pharmaceutics, 11(6), 258.

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Mitochondria-Targeted Delivery of Doxorubicin

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Branched polyethylenimine (PEI, M_w 1800 Da) and succinic anhydride (SA) were purchased from Innochem Technology Co., Ltd. (Beijing, China). 2,3-Dimethylmaleic anhydride (DMMA), PLGA (lactide : glycolide = 65 : 35, M_w 40000-75000 Da), 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT), cytochalasin D (Cyt. D), methyl-β-cyclodextrin (MBCD), sucrose, collagenase I, and collagenase IV were purchased from Sigma-Aldrich (Shanghai, Trading Co., Ltd). Polyethylene glycol monostearate (C₁₈-PEG₂₀₀₀-OH, CPO) was obtained from Tokyo Chemical Industry Co., Ltd. C₁₈-PEG₂₀₀₀-TPP (CPT) was synthesized as our previously reported 38 (link). Doxorubicin hydrochloride (DOX·HCl) was provided by Aladdin Reagent (Shanghai, China). N,N-dimethyl formamide (DMF), chloroform (CHCl₃), and isopropanol were purchased from Sinopharm Chemical Reagent Co. Ltd. (Shanghai, China). Lysotracker Green (Yeasen), Mitotracker Green (Beyotime), BCA protein assay kit (Beyotime), mitochondrial membrane potential assay kit with JC-1 (Beyotime), mitochondrial isolation kit (Beyotime), nuclei extraction kit (ExKine), XF24 extracellular flux analyzer kit (Seahorse Bioscience), and matrigel matrix (BD Biosciences) were all obtained from domestic suppliers. All other reagents and solvents were of analytical grade and used as received.

Yu H., Li J.M., Deng K., Zhou W., Wang C.X., Wang Q., Li K.H., Zhao H.Y, & Huang S.W. (2019). Tumor acidity activated triphenylphosphonium-based mitochondrial targeting nanocarriers for overcoming drug resistance of cancer therapy. Theranostics, 9(23), 7033-7050.

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Doxorubicin-Loaded Silica Nanoparticles for Cancer Therapy

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Doxorubicin (DOX), glutathione (GSH), 3-aminopropyltriethoxysilane
(APTES), tetraethyl orthosilicate (TEOS), bis[3-(triethoxysilyl)propyl]disulfide, N-trimethoxysilylpropyl-N,N,N-trimethylammonium chloride (TSA), 2,3-dimethylmaleic
anhydride (DMA), cetyltrimethylammonium bromide (CTAB), fluorescein
isothiocyanate (FITC), hyaluronic acid (HA, M_w = 10 kDa), and ammonium hydroxide were obtained from Sigma-Aldrich.
All of the chemicals and reagents used in this study were of analytical
grade and used as received without further purification. GSH was obtained
from Shanghai Macklin Biochemical Co., Ltd., and HAase was purchased
from Sigma-Aldrich.

Jin R., Liu Z., Bai Y., Zhou Y, & Chen X. (2018). Multiple-Responsive Mesoporous Silica Nanoparticles for Highly Accurate Drugs Delivery to Tumor Cells. ACS Omega, 3(4), 4306-4315.

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Cationic Polymer-Peptide Nanoparticles for VEGF Delivery

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ε-Poly(L-lysine) (PLL, M = 4200 Da) was purchased from Bonding Chemical Co., Ltd. (Texas, USA). R₉-G-NLSW peptide sequences were synthesized by Biomatik Co. (Wilmington, USA). 2,3-dimethylmaleic anhydride (DMA), diallylcarbamyl chloride (DA), 2,2-dimethoxy-2-phenylacetophenone (DMPA), triethylamine (Et₃N), dimethyl sulfoxide (DMSO) and 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2-H-tetrazolium bromide (MTT) were obtained from Sigma-Aldrich (St. Louis, MO, USA). pIRES-VEGF plasmids (pVEGF) were purchased from Sangon Biotech Co., Ltd. (Shanghai, China). Hoechst 33342 and Alexa Fluor647 labeled-oligonucleotide (AF647-oligonucleotide) were purchased from Thermo Scientific (Rockford, IL, USA). Green DND-26 (LysoTracker) was ordered from Cell Signaling Technology (Danvers, MA). iScript™ gDNA Clear cDNA Synthesis Kit and SsoAdvanced™ Universal SYBR Green Supermix was purchased from Bio-Red Co., Ltd. (Hercules, CA, USA). Human VEGF Quantikine ELISA was purchased from R&D Systems, Inc. (Minneapolis, MN, USA). Matrigel (Cat. Nos. 356234) was obtained from Corning Incorporated (New York, USA). The human dental pulp stem cells (DPSCs) were a gift from Dr. Songtao Shi, University of Pennsylvania School of Dental Medicine. Human umbilical vein endothelial cells (HUVECs) were purchased from the Lonza Company (Allendale, NJ, USA).

Li Q., Hu Z., Liang Y., Xu C., Hong Y, & Liu X. (2021). Multifunctional Peptide-Conjugated Nanocarriers for Pulp Regeneration in a Full-Length Human Tooth Root. Acta biomaterialia, 127, 252-265.

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