Sodium dihydrogen phosphate

Manufactured by Scharlab

Sourced in Spain

Sodium dihydrogen phosphate is an inorganic chemical compound with the formula NaH2PO4. It is a white, crystalline solid that is soluble in water. Sodium dihydrogen phosphate is commonly used as a buffer in various scientific applications.

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Lab products found in correlation

4 protocols using sodium dihydrogen phosphate

Analytical Method Development for MOL

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MOL, purity 98%, was obtained from Optimus Drugs Pvt LTD, India. 200 mg per capsule (R&D prepared samples) was used as the pharmaceutical formulation dosage form. American Society for Testing and Materials (ASTM) grade I water was obtained daily from the central laboratory. Potassium dihydrogen phosphate, sodium dihydrogen phosphate, dipotassium hydrogen phosphate, o-phosphoric acid, acetic acid, and anhydrous sodium acetate were supplied by Scharlau, Barcelona, Spain. The solvents used, such as acetonitrile, ethanol and methanol, were also supplied by Scharlau, Barcelona, Spain.
The chosen diluent for standard and test sample preparation was a mixture of ethanol and water in equal proportions.

Annadi A.M., El Zahar N.M., El-Din A. Abdel-Sattar N., Mohamed E.H., Mahmoud S.A, & Attia M.S. (2022). Development and validation of molnupiravir assessment in bulk powder and pharmaceutical formulation by the RP-HPLC-UV method. RSC Advances, 12(53), 34512-34519.

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Quantitative Analysis of Methylprednisolone

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Methyl Prednisolone reference standard (MP), Methyl Prednisolone hemisuccinate reference standard (MPHS), and Methylprednisolone sodium succinate working standard (MPSS) was supplied by UP pharma (Assuit, Egypt). Acetonitrile HPLC-grade, disodium hydrogen phosphate, sodium dihydrogen phosphate, glacial acetic acid 99%, hydrochloric acid 37%, sodium hydroxide, and Hydrogen peroxide 30% (Scharlau, Spain). Water for injection (WFI) was used in the analysis and passed through a 0.45 μm nylon membrane filter before use. Phosphate solution (1) was prepared by weighing 1.6 g of disodium hydrogen phosphate in 1000 mL of WFI. Phosphate solution (2) was prepared by weighing about 0.3 g of sodium dihydrogen phosphate in 1000 mL of WFI.

, & Al-Hakkani M.F. (2023). A new validated facile HPLC analysis method to determine methylprednisolone including its derivatives and practical application. Scientific Reports, 13, 11548.

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Bosentan-loaded PLGA Nanoparticles

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Poly(lactic-co-glycolic acid) polymer (50:50) (PURASORB® PDLG 5002A, inherent viscosity of 0.2 dL/g) was generously donated from PURAC (Gorinchem, Netherlands). Bosentan was supplied by Parabolic (Chandigarh, India). Polyvinyl alcohol (PVA) (98–99% hydrolyzed with Low Mwt.) was purchased from Alfa Aesar (Karlsruhe, Germany). Sodium lauryl sulfate (SLS) was obtained from Oxford (Mumbai, India). Dichloromethane (DCM), sodium dihydrogen phosphate, sodium hydroxide pellets and methanol were obtained from Scharlau (Barcelona, Spain). Pure acetone was purchased from El Nasr pharmaceutical Chemicals Co. (Cairo, Egypt). All solvents used were HPLC grade.

Hanna L.A., Basalious E.B, & ELGazayerly O.N. (2017). Respirable controlled release polymeric colloid (RCRPC) of bosentan for the management of pulmonary hypertension: in vitro aerosolization, histological examination and in vivo pulmonary absorption. Drug Delivery, 24(1), 188-198.

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Favipiravir Analytical Method Development

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Favipiravir was kindly supplied by Optrix Laboratories private Limited, India. Lamivudine, used as an internal standard (IS), was bought from LGC GmbH, Germany. Potassium dihydrogen phosphate, sodium dihydrogen phosphate, ortho phosphoric acid, acetic acid, ammonium formate and formic acid were purchased from Scharlau, Spain. Methanol and acetonitrile (HPLC grade), Sigma Aldrich, Germany.

Bendas E.R., Rezk M.R, & Badr K.A. (2023). Does the Ethnic Difference Affect the Pharmacokinetics of Favipiravir? A Pharmacokinetic Study in Healthy Egyptian Volunteers and Development of Level C In-vitro In-vivo Correlation. Drug research, 73(6).

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