Irinotecan hydrochloride, curcumin, poloxamer 105, mannitol, and dimethyl sulfoxide (DMSO) were purchased from Sigma-Aldrich and used as received (USA). Dulbecco’s modified Eagle’s medium (DMEM; pH 7.5) and HQ fetal bovine serum (FBS) were purchased from TransGen Biotech Co., Ltd. (Beijing, China). Wortmannin, cytochalasin D, genistein, and methyl-β-cyclodextrin were purchased from Meilun Biotechnology Co., Ltd. (Dalian, China). Chlorpromazine was obtained from Selleck Chemicals (Shanghai, China). Hydrochloric acid was purchased from Chengdu Kelong Chemical Reagent Factory (Chengdu, China). Phosphate-buffered saline (PBS; pH 7.4) was prepared in the laboratory, and ultrapure water was produced using a Milli-Q integral water purification system.
Poloxamer 105
Manufactured by Merck Group
Sourced in United States
Poloxamer 105 is a nonionic triblock copolymer composed of a central hydrophobic chain of polyoxypropylene (polypropylene glycol) flanked by two hydrophilic chains of polyoxyethylene (polyethylene glycol). It is a white, waxy solid used as a surfactant and emulsifier in various pharmaceutical and cosmetic applications.
Automatically generated - may contain errors
Lab products found in correlation
Irinotecan hydrochloride, by Merck Group (3 mentions)
Mannitol, by Merck Group (3 mentions)
Curcumin, by Merck Group (3 mentions)
Chlorpromazine, by Selleck Chemicals (2 mentions)
Wortmannin, by Meilun (2 mentions)
Cytochalasin d, by Meilun (2 mentions)
Genistein, by Meilun (2 mentions)
Dimethyl sulfoxide (dmso), by Merck Group (2 mentions)
Hydrochloric acid (hcl), by Chron Chemicals (1 mentions)
Hq fetal bovine serum, by Transgene (1 mentions)
Fetal bovine serum (fbs), by Thermo Fisher Scientific (1 mentions)
Trypsin, by Thermo Fisher Scientific (1 mentions)
Mito tracker red cmxros, by Beyotime (1 mentions)
Penicillin streptomycin, by Thermo Fisher Scientific (1 mentions)
Ros detection kit, by Keygen Biotech (1 mentions)
Topotecan hydrochloride, by Merck Group (1 mentions)
Glucose, by Merck Group (1 mentions)
Paraformaldehyde (pfa), by Merck Group (1 mentions)
3 protocols using poloxamer 105
1
Nanoformulation for Drug Delivery
2
Irinotecan-Curcumin Nanoformulation Cytotoxicity
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Irinotecan hydrochloride, curcumin, poloxamer 105, mannitol, dimethyl sulfoxide (DMSO), and DMEM Mixture F-12 Ham (DMEM/F12) were purchased from Sigma-Aldrich (St Louis, MO, USA) and used as received. Phosphate Buffered Saline (PBS, pH = 7.4) was prepared in the lab and ultrapure water was produced using a Milli-Q integral water system (Millipore, MA, USA).
MitoTracker Red CMXRos was purchased from Beyotime Biotechnology Inc (P.R. China).
Annexin V apoptosis detection kit FITC and ROS detection kit were purchased from KeyGEN Biotech (Nanjing, P.R. China). Penicillin-streptomycin, fetal bovine serum, and trypsin were purchased from Gibco (Grand Island, NY, USA)
MitoTracker Red CMXRos was purchased from Beyotime Biotechnology Inc (P.R. China).
Annexin V apoptosis detection kit FITC and ROS detection kit were purchased from KeyGEN Biotech (Nanjing, P.R. China). Penicillin-streptomycin, fetal bovine serum, and trypsin were purchased from Gibco (Grand Island, NY, USA)
3
Nanoparticle Formulation for Drug Delivery
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Irinotecan hydrochloride, topotecan hydrochloride, curcumin, po-loxamer 105, mannitol, glucose, paraformaldehyde and dimethyl sulfoxide (DMSO) were purchased from Sigma-Aldrich and used as received. Wortmannin, cytochalasin D, genistein and methyl-p-cyclodextrin were purchased from Meilun Biotechnology Co. Ltd (Dalian, China). Chlorpromazine was obtained from Selleck Chemicals (China). Phosphate buffered saline (PBS, pH = 7.4) was prepared in laboratory and ultrapure water was produced using a Milli-Q integral water purification system.
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