Avatar 330 ftir spectrometer

FT-IR spectroscopic study was performed using an Avatar 330 FT-IR spectrometer (Thermo Nicolet, Waltham, MA, USA) to investigate the interactions between MEL and Soluplus^®. Pastilles from the samples and 0.15 g potassium bromide were formed using a Specac^® hydraulic press (Specac, Inc., USA) by 10 t pressing force. The infrared spectra of the pastilles were collected in the range of 400–4000 1/cm with deuterated triglycine sulfate detector. The spectral resolution was set at 4 1/cm and 128 parallel scans were averaged.

The FTIR spectroscopy measurements were recorded to characterize the probable participation of the functional groups of cisplatin in synthesized PLGA-cisplatin. The FTIR spectra of PLGA-cisplatin NPs were acquired in an Avatar 330 FTIR spectrometer (Thermo Fisher Scientific, Waltham, MA, USA) over a scale of 4,250–500 cm⁻¹ after adding with KBr pellets [32 (link)].

The interactions between PRX and the excipients were investigated using an AVATAR 330 FT-IR spectrometer (Thermo Nicolet, Thermo Fisher Scientific Inc., Waltham, MA, USA). The raw materials were combined into physical mixtures (PM) with the same composition as OL. The samples were homogenized with 150 mg of KBr in an achate mortar, and the mixture was pressed to make pastilles using a Specac^® hydraulic press (Specac, Inc., Washington, PA, USA) by 10 ton pressing force. The infrared spectra were recorded between 4000 and 400 cm⁻¹, at an optical resolution of 4 cm⁻¹.

The determination of the success of functionalization procedure and the nature of TNT–carboxylic acid interactions were evaluated using an Avatar 330 FT-IR spectrometer (Thermo Fisher Scientific Ltd., Waltham, MA, USA). FT-IR measurements were conducted with a transmission E.S.P. accessory by using 128 scans at a resolution of 4 cm⁻¹ and applying H₂O and CO₂ corrections. Spectragryph 1.2.16.1 software (Friedrich Menges, Obersdorf, Germany) was used to evaluate the results.
A DXR Dispersive Raman spectrometer (Thermo Fisher Scientific Inc., Waltham, MA, USA) equipped with a CCD camera and a diode laser operating at a wavelength of 780 nm was applied to perform Raman measurements, which were carried out with a laser power of 12 and 24 mW at 25 μm slit aperture size. The data were collected in the spectral range of 200–3300 cm⁻¹ using photobleaching to compensate fluorescence of titanate. OMNIC 8 software was used for data collection, averaging the total of 20 scans and making the spectral corrections. For the removal of cosmic rays, a convolution filter was applied on the original spectrum using Gaussian kernel.

The interactions between IBU and the excipients were investigated by the AVATAR 330 FT-IR spectrometer (Thermo Nicolet, Thermo Fisher Scientific Inc., Waltham, MA, USA). The sample was homogenized with 150 mg of dry KBr in an achate mortar, and the mixture was pressed to create pastilles using a Specac^® hydraulic press (Specac, Inc., Orpington UK) with 10-ton pressing force. The infrared spectra were recorded between 4000 and 400 cm⁻¹, at an optical resolution of 4 cm⁻¹.