Dx chemistry analyzer

Manufactured by IDEXX

The Dx Chemistry Analyzer is a diagnostic instrument designed for performing a variety of clinical chemistry tests. It is capable of analyzing a range of analytes from various sample types, including serum, plasma, and urine. The Dx Chemistry Analyzer provides automated processing and accurate results to support veterinary healthcare professionals in making informed clinical decisions.

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Lab products found in correlation

4 hne, by MyBioSource (1 mentions) Il 17, by R&D Systems (1 mentions) Il 1β, by R&D Systems (1 mentions) Il 12, by R&D Systems (1 mentions) Il 18, by R&D Systems (1 mentions) Hmgb1, by Shino-Test (1 mentions)

Close spelling variants of this product

Catalyst Dx Chemistry Analyzer Catalyst Dx Chemistry Analyzer system

2 protocols using dx chemistry analyzer

Toxicity Assessment of SHetA2 in Rodents

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Animals were examined daily for any external signs of toxicity that would be predicted to shorten the natural life span of the animal, such as roughened coat, chromodacryorrhea, rhinitis, and prostration. Body weights were recorded at weekly intervals. Organ-to-body weight ratios were determined at weeks 1, 2 and 3. Sections of paraffin-embedded organ specimens were stained with hematoxylin and eosin (H&E) for pathology review. Three serum specimens from each of the groups treated for 6 weeks with 500 ppm, 750 ppm and 1000 ppm SHetA2 diets were evaluated for liver and kidney function tests: alanine amino transferase (ALT), aspartate amino transferase (AST), alkaline phosphatase (ALKP) and blood urea nitrogen (BUN) and creatinine (CRE) using an IDEXX Catalyst Dx Chemistry Analyzer.

Benbrook D.M., Janakiram N.B., Chandra V., Pathuri G., Madka V., Stratton N.C., Masamha C.P., Farnsworth C.N., Garcia-Contreras L., Hatipoglu M.K., Lighfoot S, & Rao C.V. (2017). Development of a dietary formulation of the SHetA2 chemoprevention drug for mice. Investigational New Drugs, 36(4), 561-570.

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Quantifying Inflammatory and Oxidative Markers

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Commercially available enzyme linked immunosorbant assay (ELISA)
kits were used to measure the concentrations of HMGB1 (#ST51011,
Shino Test Corporation), IL-1β (#MLB00C, R&D Systems),
IL-18 (#7625, R&D Systems), IL-12 (#DY419, R&D
Systems), IL-17 (#DY421, R&D Systems), LDH (#ab102526,
Abcam), MDA (#ab118970, Abcam), 4-HNE (#MBS702101,
MyBioSource), DAG (#MET-5028, Cell Biolabs Inc.), and IP3
(LS-F10644-1, LifeSpan Biosciences Inc.) in serum, culture medium, or whole
cell lysate according to the manufacturer’s instructions.
Measurement of serum tissue enzymes (CK, BUN, and ALT) were performed using
the IDEXX Catalyst Dx® Chemistry Analyzer according to the
manufacturer’s protocol.

Kang R., Zeng L., Zhu S., Xie Y., Liu J., Wen Q., Cao L., Xie M., Ran Q., Kroemer G., Wang H., Billiar T.R., Jiang J, & Tang D. (2018). Lipid Peroxidation Drives Gasdermin D-mediated Pyroptosis in Lethal Polymicrobial Sepsis. Cell host & microbe, 24(1), 97-108.e4.

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