Il 17

Manufactured by MyBioSource

Sourced in United States

IL-17 is a cytokine that plays a crucial role in the immune system's inflammatory response. It is primarily produced by T helper 17 (Th17) cells and acts on various cell types to promote the secretion of proinflammatory mediators. The core function of IL-17 is to coordinate the recruitment, activation, and migration of immune cells to sites of inflammation.

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Lab products found in correlation

Il 10, by MyBioSource (2 mentions) Il 10, by Cusabio (1 mentions) Ifn γ, by Cusabio (1 mentions) Il 17, by R&D Systems (1 mentions) Lipopolysaccharides (lps), by MyBioSource (1 mentions) Il 1β, by MyBioSource (1 mentions) Interleukin 6 (il 6), by MyBioSource (1 mentions) Tnf α, by MyBioSource (1 mentions) Gsh px, by MyBioSource (1 mentions) Il 22, by MyBioSource (1 mentions)

3 protocols using il 17

Serum Levels of Immune Biomarkers

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ELISA-based serum levels of interferon-γ (IFN-γ) (Cusabio, China), interleukin-17 (IL-17) (Mybiosource, USA), interleukin-10 (IL-10) (Cusabio, China), beta-defensin, and lipocalin-2 (LCN-2) (Mybiosource, USA) were determined.

Gad El-Karim D.R., El-Amrawi G, & Salama A.R. (2024). Clinicopathological studies on ulcerative lymphangitis in cattle: Alterations in serum inflammatory cytokines, anti-microbial, organs functions, and oxidative stress-related biomarkers. Open Veterinary Journal, 14(1), 25-31.

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Cytokine and Oxidative Stress Profiling

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Blood was collected from the mice in each group and subsequently centrifuged at 4000 rpm for 10 min. The levels of MCP-1, tumor necrosis factor-α (TNF-α) and interferon-γ (IFN-γ) in the obtained sera were measured utilizing ELISA sets (Becton Dickinson).
In the case of reactive oxygen species (ROS), IL-17, IL-10 and Foxp3, ELISA kits were used: ROS (MyBiosource, San Diego), IL-17 (R & D Systems, Minneapolis), IL-10 (Chondrex, Redmond), Foxp3 (Cloud-Clone, Houston) These assays were conducted according to the protocols provided by the above manufacturers.

Mukai S., Ogawa Y., Saya H., Kawakami Y, & Tsubota K. (2018). Therapeutic potential of tranilast for the treatment of chronic graft-versus-host disease in mice. PLoS ONE, 13(10), e0203742.

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Evaluation of LPS-Induced Metabolic Effects

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LPS (Escherichia coli 055:B5) were obtained from Aladdin (Beijing, China). De Man, Rogosa, and Sharpe (MRS) was from Solarbio Ltd. (Solarbio, Beijing, China). Total cholesterol (TC), triglyceride (TG), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), ALT, AST, MDA, T-AOC, SOD, GSH-Px, CAT, TNF-α, transforming growth factor (TGF)-β, IL-1β, IL-6, IL-17, IL-10, IL-22, and LPS kits were obtained from MY BioSource Co., Ltd. (San Diego, CA, USA).

Guo W., Mao B., Tang X., Zhang Q., Zhao J., Cui S, & Zhang H. (2022). Lactobacillus paracasei CCFM1223 Protects against Lipopolysaccharide-Induced Acute Liver Injury in Mice by Regulating the “Gut–Liver” Axis. Microorganisms, 10(7), 1321.

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