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182 protocols using spss 26.0 for windows

1

Probiotic Consumption and Cost Analysis

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We applied Sankey Diagrams by RAWGraghs 2.0 (https://www.rawgraphs.io/) to visualize the source of prescriptions. We analyzed the consumption and expenditure of probiotics as a whole and separately according to different formulations and strains. The average cost per visit was the yearly probiotic expenditure divided by the number of probiotic prescriptions. The statistical significance of trends for the usage and cost of total probiotics was analyzed using the Mann-Kendall test. Other probiotic trends were estimated using the Cochran-Armitage trend test R V.3.3.0 (http://www.R-project.org). We demonstrate the mixture of different probiotic strains by Gephi software (version 0.9.4). Backward stepwise multivariable logistic regression with SPSS 26.0 for Windows (SPSS, Inc, Chicago, Ill) investigated risk factors for antitumor agents co-prescribed with probiotics. Variables with p < 0.2 in single-variable comparisons were included in a multivariable logistic regression model. A two-tailed p < 0.05 was considered to be statistically significant. Relative risk was estimated using odds ratios (ORs) with corresponding 95% confidence intervals (CIs). The Spearman’s rank correlation coefficient with SPSS 26.0 for Windows (SPSS, Inc, Chicago, Ill) calculated correlations between probiotic strain and antitumor drug usage. A p-value less than 0.05 is statistically significant.
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2

Statistical Analysis of Ct Value Trends

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Baseline characteristics were summarized using descriptive statistics including proportion, mean and standard deviation. Slopes of Ct values were calculated by linear regression. Student's t-test and the Mann-Whitney test were used to compare continuous variables, and the χ2 test or Fisher's exact test were used to compare categorical variables. All P values were two-tailed, and values < 0.05 were considered to be statistically significant. All statistical analyses were performed using SPSS 26.0 for Windows (SPSS, Chicago, IL, USA), while GraphPad Prism 5.01 (GraphPad Software, San Diego, CA, USA) was used for figure development.
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3

Obesity Indices and Metabolic Syndrome

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Statistical analysis was performed using SPSS 26.0 for Windows (SPSS Inc. Chicago, USA). Data are presented as number (percentage), mean (± standard deviation), or median (25th-75th percentile) for TGs. Differences between groups were analyzed using the independent t-test for continuous variables and chi-square test for categorical variables. Multiple logistic regression analysis was used to identify factors associated with MetS. Covariates in the multivariable model included age, systolic and diastolic blood pressures, total cholesterol, LDL-C, eGFR and medications use. An interaction p in Logistic analysis: Model disease (y)= x1 +x2 + x1*x2 +covariates x1*x2 was interaction term. In this study, y = MetS; x1 = sex; x2 = each obesity-related index; covariates = age, systolic and diastolic blood pressures, total cholesterol, LDL-C, eGFR and medications use. Receiver operating characteristic (ROC) curves and areas under the ROC curves (AUCs) were used to assess the performance and predictive ability, respectively, of the obesity-related indices in identifying MetS. A difference was considered significant if the p value was less than 0.05.
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4

Analyzing Clinical Characteristics and Sociodemographic Factors in Mental Health Services

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Statistical analysis was performed using the Statistical Package for Social Sciences (SPSS) 26.0 for Windows (SPSS Inc., IBM, New York). For clinical characteristics and toxicology data, as well as previous suicide attempts and DSH, we utilized simple ratios and percentage calculations. Sociodemographic variables were compared between those who did and did not attend MHSs utilizing the independent Student t-test for parametric data (clinical and sociodemographic data), and the χ2 test or, where there was a small sample size, the Fishers’ exact test for nonparametric data.
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5

Evaluating Vaccination Impact on Health

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Categorical variables were described using frequencies and percentages. Continuous variables were described by mean and standard deviation. Comparison between answers regarding vaccinated and unvaccinated patients was utilized using paired samples t-test. P < 0.05 was defined as statistically significant. The effect size of significant results was calculated using Cohen’s d test. The internal consistency of each tool in the study instrument was measured using the alpha Cronbach score (alpha above 0.7 is considered high). Correlations were examined using the Pearson correlation coefficient. The analysis was performed using SPSS 26.0 for Windows.
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6

Non-parametric Statistical Analysis in Research

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Data are presented as the mean, range, median, or number (percentage) as appropriate. Statistical significance between the two groups was determined using the Kruskal-Wallis test, a non-parametric method for testing whether samples originate from the same distribution. In addition, between two groups comparison were conducted using the Wilcoxon signed rank test, a non-parametric statistical test. Statistical analysis was performed using GraphPad Prism (Version 9.0, GraphPad Software, San Diego, CA, USA), R statistics package (R Foundation, Vienna, Austria; https://www.r-project.org), and SPSS 26.0 for Windows (SPSS Inc., Chicago, IL, USA). P values < 0.05 were considered significant.
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7

Vibration Perception Threshold Analysis

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Data on characteristics of the participants are given as median (range) unless otherwise stated, while results from the vibration perception threshold analyses are reported as median [IQR].
We tested for differences of continuous variables between groups using non‐parametric Mann–Whitney U‐test and within groups by Wilcoxon signed rank test. Correlations were performed using Spearman rank sum test and expressed as a coefficient (rs) with a level of significance. p < 0.05 was considered statistically significant. Statistical analysis was performed using SPSS 26.0 for Windows (SPSS Inc.).
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8

Multivariate Survival Analysis of Patient Data

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R version 44.1.2 and SPSS 26.0 for Windows were used to analyze all the data. The packages of R include “tableone”, “survival”, “plyr”, “ggplot2”, and “foreign”. First, we conducted the descriptive analysis by t-test (normally distributed continuous variables), Kruskal test (nonnormally distributed continuous variables), or the chi-squared test (categorical variables). Univariate survival analysis was performed by plotting the Kaplan-Meier curve and log-rank test. Finally, we analyzed the independent factors by LASSO and Cox multivariate hazard regression analysis. All tests were two-sided, and a P value of <0.05 was considered to be statistically significant. The missing value was not interpolated.
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9

Correlation Analysis of Distance and Angle Measurements

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The data were analyzed using SPSS 26.0 for Windows, with Pearson correlation coefficients calculated for each sex group. Mean values of distance and angle measurements were calculated with standard deviations and 95% CIs. P values were calculated under a predetermined significance level (0.05), and a 95% CI was constructed. Results were expressed as percentages, mean ± standard deviation for variables. Appropriate tables were used during data analysis.
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10

Survival Analysis of Lymphoma Subtypes

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The Statistical Package of Social Sciences (SPSS 26.0 for Windows) was used. The χ2 test was used to test the relationship between HGL-DH, DLBCL-CNG, and DLBCL without DH-CNG and clinical as well as pathological parameters. Differences concerning overall survival and recurrence free survival between HGL-DH, DLBCL-CNG, and DLBCL without DH-CNG were analyzed by the Kaplan-Meier method and compared by the log rank test. A multivariate analysis was performed to identify independent prognostic markers for OS and RFS using a Cox multistep regression model. A p value < 0.05 was considered significant.
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