16 slice brilliance big bore computed tomography scanner

In total, 33 patients with cervical cancer who received concurrent chemoradiotherapy in Shandong Cancer Hospital from 2019 to 2020 were recruited. All patients received 45–50 Gy/25 fractions of pelvic intensity-modulated photon therapy (IMRT) combined with concurrent cisplatin chemotherapy. Each patient underwent CT and multi-sequence MR simulation scans. CT scans were performed using a Philips 16-slice Brilliance big-bore computed tomography scanner (Philips Medical Systems, Amsterdam, Netherlands) with a 3-mm slice gap thickness and 3-mm slice. The patients were immobilized in the supine position with thermoplastic molds or in the prone position with an abdominal pelvic fixator. Magnetic resonance imaging (MRI) was performed using a 3.0T superconducting MR scanner (Discovery 750w, GE Healthcare, USA) with the same position and fixed device as those used for the CT scans. All patients underwent T1WI, T2fs, and IDEAL IQ sequence scans with 3 mm slice thickness. The IDEAL IQ sequence scans were reconstructed to obtain the fat fraction (FatFrac IDEAL IQ) images.

A total of 15 patients diagnosed with FIGO Stage IIB cervical cancer and treated with cCRT in our hospital between June 1st 2019 and July 30th 2019 were selected for the present study, and patients’ information is shown in Table 1. All the patients undergone external beam radiotherapy (EBRT), brachytherapy, and concurrent chemotherapy. Before EBRT, all the patients were scanned using a Philips 16-slice Brilliance big bore computed tomography scanner (Philips Medical Systems, Amsterdam, Netherlands) with 5 mm slice thickness images, collected from the upper border of L2 vertebra to the region of 5 cm below the ischial tuberosities. All the patients were immobilized with thermoplastic mold in a supine position with comfortably full bladder and bowel preparation prior to simulation (after bladder emptying, patients were requested to drink 800 ml of water with 40 ml 60% Meglumine Diatrizoate 1 h before treatment and hold their urine). The CT scan images were transmitted into the Pinnacle³ 9.10 (Philips Medical Systems, Cleveland, USA) planning system for targets and OARs contouring. The CT scan images and RT structures were transmitted to the Monaco 5.11 (Elekta AB, Stockholm, Sweden) planning system and Tomotherapy planning system (TomoTherapy Inc., Madison, WI) for radiotherapy planning design.

A Philips 16-slice Brilliance big-bore computed tomography scanner (Philips Medical Systems, Amsterdam, Netherlands) with 3 mm slice thickness and 3 mm slice gap was used for imaging. The scans were made from the upper border of the T2 vertebra to the middle of the femur. Patients were immobilized with thermoplastic mold in a supine position or immobilized with an abdominal pelvic fixator in a prone position.