Children ages 9–11 were scanned with a 3-T whole-body scanner using a 32-channel head coil (Ingenia; Philips Healthcare), providing T1-weighted structural and functional images (TR = 1075 ms, 290 vol per participant). Images were acquired on a Phillips Healthcare Ingenia 3 T whole-body scanner with a 32-channel head coil. For the T1-weighted structural scans, the imaging parameters were: T1 3D TFE (Turbo Field Echo) pulse sequence, 8° flip angle, FOV 240 mm, matrix size 240 × 240, slice thickness 1 mm. For task-based MRI, echoplanar images were collected with the following parameters: TR = 1075 ms, TE = 30 ms, 55° flip angle, single excitation per image, FOV 240 mm, matrix size 80 × 80, slice thickness 3 mm, 48 slices. Three runs of 290 vol were collected for each participant.
Ingenia 3
Manufactured by Philips
Sourced in China
Ingenia 3.0 is a magnetic resonance imaging (MRI) system manufactured by Philips. It is designed to capture high-quality images of the human body. The Ingenia 3.0 operates at a magnetic field strength of 3.0 Tesla, which enables it to produce detailed and accurate imaging data.
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13 protocols using ingenia 3
1
Neuroimaging of Executive Function in Children
2
Distortion-Robust Brain Imaging for Stroke
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We examined our FastCSR method on three stroke patients whose brains were distorted due to severe cerebral hemorrhage. Their T1w images were acquired on a Philips Ingenia 3 T scanner (Philips Healthcare, Best) with a sagittal 3D T1w sequence (TR = 1000 ms, TE = 2.15 ms, flip angle = 8°, FOV = 256 × 256, voxel size = 1 × 1 × 1 mm3) at the China Rehabilitation Research Center, Beijing, China. Written informed consent was obtained from each participant in accordance with guidelines and regulations previously approved by the Medical Ethics Committee of China Rehabilitation Research Center.
3
Nephrogeriatric Brain MRI Protocol
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As part of routine nephro-geriatric work-up a brain MRI was performed in all patients without a contra-indication for MRI. Contraindications for not performing a MRI were: having a pacemaker, having a metallic foreign body (metal sliver) in their eye, being claustrophobic, or not being able to have access to the MRI table due to backpain or impaired mobility. Brain MRI scans were acquired on a Philips Ingenia 3 T scanners at the LUMC (Philips Medical Systems, Best, The Netherlands) according to a standardized scanning protocol. The scanning protocol included T1-weighted images (repetition time (TR) = 8.2 ms; echo time (TE) = 4.5 ms; flip angle 8°, voxel size 1x1x1mm3), fluid-attenuated inversion recovery (FLAIR) images (TR = 4800 ms; TE = 313 ms; inversion time (TI) = 1650 ms; voxel size 1.11 × 1.11 × 1.11mm3) and susceptibility-weighted imaging (TR = 45 ms; TE 31 ms; flip angle 13°; voxel size 0.8 × 0.8 × 1.6mm3). The brain MRI scans were scored for markers of small vessel disease (white matter hyperintensities) and lacunes of presumed vascular origin and microbleeds) according to the STRIVE criteria [34 (link)]. White matter hyperintensities were assessed by the Scheltens scale [35 (link)].
4
Knee MRI Acquisition Protocol
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MRI was performed on a 3 T-MRI scanner (Ingenia 3.0, Philips Healthcare) using a knee coil (8-Channel-Knee-Coil, Philips Healthcare). The protocol included a 3D-T1-weighted FFE sequence in transverse orientation (TR 6.1 ms, TE 2.3 ms, flip angle 35°, field of view 180 × 180, in-plane resolution 0.625 × 0.625 mm2, slice thickness 1.2 mm, spacing between slices 0.6 mm), a T1-weigthed TSE in sagittal (TR 1120 ms, TE 10.8 ms, flip angle 90°, FOV 150 × 150, in-plane resolution 0.174 × 0.174 mm2, slice thickness 2.0 mm, spacing between slices 2.2 mm), and coronal orientation (TR 855 ms, TE 10.8 ms, flip angle 90°, FOV 150 × 150, in-plane resolution 0.188 × 0.188 mm2, slice thickness 2.0 mm, spacing between slices 2.2 mm).
5
High-Resolution Rectal MRI Imaging Protocol
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All MRI examinations were performed in the supine position on a 3.0-Tesla (T) scanner (Ingenia 3.0, Philips Medical System, Best, The Netherlands) with an eight-channel phased-array surface coil. There was no bowel preparation or intravenous antispasmodic agents administered. High-resolution rectal MRI protocols included transverse DWI and T2WI, and sagittal fat-suppression T2WI. The acquisition parameters for transverse T2WI included: repetition time (TR)/echo time (TE), 2200/65 ms; flip angle, 90°; matrix size, 288 × 288; field of view (FOV), 250 × 250 mm2; slices, 20; slice thickness, 5 mm; spacing between slices, 0.5 mm; and NSA, 2. The parameters for DWI included: TR/TE, 6000/76 ms; flip angle, 90°; matrix size, 288 × 288; FOV, 450 × 450 mm2; slices, 48; slice thickness, 5 mm; spacing between slices, 1 mm; and b values, 0 and 1,000 s/mm2.
DWI and T2WI images were exported from the Picture Archiving and Communication System at our institution. ADC maps were generated using MATLAB 2018a (Mathworks, Natick, MA, United States) according to loaded DWI images using the following formula: ADC = (lnSI0-lnSI)/(b-b0), where SI0 and SI represent signal intensity at b values of 0 and 1,000 s/mm2, respectively.
DWI and T2WI images were exported from the Picture Archiving and Communication System at our institution. ADC maps were generated using MATLAB 2018a (Mathworks, Natick, MA, United States) according to loaded DWI images using the following formula: ADC = (lnSI0-lnSI)/(b-b0), where SI0 and SI represent signal intensity at b values of 0 and 1,000 s/mm2, respectively.
6
Optimized MRI Imaging of Diannan Swine Brains
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All MRI scans were performed using a 3.0T MRI scanner (Ingenia 3.0; Philips) to collect MRI images of the brains of Diannan small‐ear pigs. The pigs were anesthetized with 3% pentobarbital sodium and were then placed on the scanning bed. A horizontal scanning frame with an inner diameter of 16cm and a volume or surface coil for scanning the Diannan small‐ear pigs were used in the process. The physiological parameters of the experimental animals were continuously and dynamically monitored, including the heart rate (HR), respiratory rate (RR), temperature (T), and so forth. Body temperature was maintained at about 37°C with a heating blanket.
7
Gadoxetic Acid Contrast-Enhanced MRI Protocol
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All MR examinations were performed on either 1.5 T (n = 43, Achieva 1.5, Philips Medical Systems) or 3 T (n = 108, Achieva 3.0 T and Ingenia 3.0 T, Philips Medical Systems; Vantage Tital 3 T, Canon Medical Systems) clinical MR systems. The baseline MRI examinations included a single-shot turbo spin-echo, breath-hold gradient dual-echo T1-weighted (in-phase and opposed-phase), fat-suppressed fast spin-echo T2-weighted, diffusion-weighted (b = 0, 500, and 1000 s/mm2, applied in three orthogonal directions), and dynamic contrast-enhanced sequences. The dynamic contrast-enhanced sequences were obtained using a 3D fat-suppressed T1-weighted spoiled gradient-recalled echo pulse sequence. After obtaining precontrast images, intravenous gadoxetic acid (Primovist, Bayer Pharma) was administered at a dose of 0.025 mmoL/kg body weight at a rate of 2.0 mL/sec, followed by a 20-mL saline flush at 1.0–2.0 mL/sec. Postcontrast images were obtained during the arterial phase (27–40 s using fluoroscopic triggering technique), portal venous phase (70 s), and transitional phase (120 s) images after an intravenous administration of gadoxetic acid. HBP images were obtained 20 min after the administration of contrast agent.
8
MRI Protocol for Abdominal Imaging
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The patients lay on the scanning bed in a supine position without bowel preparation or intravenous injection of antispasmodics. An axial HR-T2WI sequence and axial DWI sequence were conducted during the MRI examination, using an eight-channel phased array surface coil. Eighty-nine patients were examined with a 3.0 Tesla (T) MRI scanner (Ingenia 3.0; Philips Medical System, Best, The Netherlands). The acquisition parameters were as follows: repetition time/echo time, 6,000/76 ms; flip angle, 90°; matrix size, 576 × 576; field of view, 450 mm; slices, 48; slice thickness, 5 mm; spacing between slices, 1 mm; b values, 0 and 600 s/mm2. Sixty-five patients were imaged with another 3.0T MRI scanner (Signa HDxt, GE Healthcare). The acquisition parameters were as follows: repetition time/echo time, 6540/130 ms; flip angle, 90°; matrix size, 320 × 320; field of view, 360 mm; slices, 45; slice thickness, 5 mm; spacing between slices, 1 mm; b values, 0 and 600 s/mm2.
9
High-Resolution T1-Weighted MRI Protocol
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Sagittal 3D high-resolution T1-weighted data were collected by a turbo field echo (TFE) sequence. The parameters are as followed: repetition time (TR)/echo time (TE) = 7.0 ms/3.2 ms; field of view = 256 mm × 256 mm; matrix = 256 × 256. The thickness slice is 1.0 mm, and there were 192 slices with no gap (Ingenia 3.0, Philips).
All the structural MRI data were preprocessed utilizing CAT12 software (version r1364) with the accompanying methodology: bias correction, segmentation, the creation of population-specific tissue templates, spatial normalization using the DARTEL technique, and smoothing with an 8 mm × 8 mm × 8 mm full-width. After these preprocessing steps, we acquired the normalized, modulated, and smoothed GMV images, and each voxel represented volume information.
All the structural MRI data were preprocessed utilizing CAT12 software (version r1364) with the accompanying methodology: bias correction, segmentation, the creation of population-specific tissue templates, spatial normalization using the DARTEL technique, and smoothing with an 8 mm × 8 mm × 8 mm full-width. After these preprocessing steps, we acquired the normalized, modulated, and smoothed GMV images, and each voxel represented volume information.
10
Diffusion-Weighted MRI Protocol for 3.0T
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All MRI examinations were performed on a 3.0-Tesla (T) scanner (Ingenia 3.0, Philips Medical System, Best, The Netherlands) with an eight-channel phased-array surface coil in the supine position. There was no bowel preparation or intravenous antispasmodic agents administered. An axial DWI sequence was performed for all patients. The acquisition parameters were as follows: Repetition time/echo time, 6000/76 ms; flip angle, 90°; matrix size, 288 × 288; field of view, 450 mm; slices, 48; slice thickness, 5 mm; spacing between slices, 1 mm; b values, 0 and 1000 s/mm2.
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