In this study we used three monovalent vaccines; inactivated M. hyopneumoniae bacterin (RespiSure‐One, Zoetis, Serial No. 185372), modified‐live PRRSV vaccine (Fostera PRRS, Zoetis, Serial No. SN163540/159469, Lot No. 169588), and PCV2 subunit vaccine (Ingelvac CircoFLEX, Boehringer Ingelheim Vetmedica, Serial No. 3091076A) which were prepared and administered according to the manufacturer's instruction. A trivalent M. hyopneumoniae‐PCV2‐PRRSV vaccine (Ingelvac 3FLEX vaccine, Boehringer Ingelheim Vetmedica; Ingelvac CircoFLEX, Serial No. 3091076A; Ingelvac MycoFLEX, Serial No 270472A; Ingelvac PRRS MLV, Serial No. 2451124B) was prepared according to manufacturer's mixing instructions and was also used.
Respisure one
Manufactured by Zoetis
Sourced in United States
RespiSure-One is a vaccine developed by Zoetis for the prevention of Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) in pigs. It is a single-dose injectable vaccine that stimulates the immune system to produce antibodies against the PRRSV.
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2 protocols using respisure one
1
Evaluation of Monovalent and Trivalent Swine Vaccines
2
Piglet Vaccination for Respiratory Health
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The experimental protocol (AUP00001125) was approved by the University of Alberta Animal Care and Use Committee–Livestock in accordance with the Canadian Council on Animal Care guidelines. The animals used for this study have been described previously [28] (link). Briefly, piglets (n = 117) were vaccinated intramuscularly with one dose (1 mL) of RespiSure-One (Zoetis, U.S.A) at 28 days of age (Day 0) and received a booster vaccination at 52 days of age (Day 24). The trial was terminated when piglets were 63 days of age (Day 35). Bodyweight was recorded at 0- (Birth), 24- (Weaning), and 63-days of age. A nasal swab from each piglet was tested prior to vaccination on Day 0 to confirm the piglets were negative for M. hyopneumoniae. Maternal serological status was not measured for sows in this study, but animals within the facility had been reported as M. hyopneumoniae-free at the time of this study and for several years prior to this study. Sows were not vaccinated with RespiSure-One to reduce the possibility that vaccine-induced antibodies measured in piglets were of maternal origin.
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