Before the start of the experiment, another week of environmental adaptation was carried out. For the diabetic group, 45 mg/kg streptozocin (STZ; Solarbio Beijing) was intraperitoneally injected for one week, while the same volume of saline was injected into the controls. During the week of drug injection, we trained the mice on the Y maze for the first six days and performed the final behavioral test on the seventh day. The blood glucose in caudal venous was detected every two days. When random blood glucose > 16.7 mmol/L [34 (link)], they were considered diabetic.
Streptozocin
Manufactured by Solarbio
Sourced in China
Streptozocin is a chemical compound primarily used as a research tool in the laboratory setting. It functions as a naturally occurring nitrosourea compound, demonstrating cytotoxic properties. Streptozocin is commonly utilized in studies involving diabetes research and the investigation of various disease models.
Automatically generated - may contain errors
Lab products found in correlation
2 protocols using streptozocin
1
Streptozocin-Induced Diabetic Mouse Model
2
Vitamin A and Cerulein-Induced Pancreatitis
Check if the same lab product or an alternative is used in the 5 most similar protocols
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Vitamin A palmitate (CAS NO. 79-81-2, Aladdin, China) was dissolved in corn oil and introduced by gavage or intraperitoneal injection. Cerulein (Stock NO. HY-A0190) was purchased from MedChemExpress, USA. Streptozocin (Code NO. S8050) was obtained from Solarbio, China.
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