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Coutaric acid

Manufactured by Merck Group
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Coutaric acid is a chemical compound that is used in laboratory settings. It serves as a reference standard for analytical procedures. The core function of Coutaric acid is to provide a consistent and reliable reference point for various analytical techniques.

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Lab products found in correlation

Catechin, by Merck Group (5 mentions) Epicatechin, by Merck Group (5 mentions) Gallic acid, by Merck Group (4 mentions) Citric acid, by Merck Group (3 mentions) Methanol, by Thermo Fisher Scientific (3 mentions) Acetonitrile, by Thermo Fisher Scientific (3 mentions) L tryptophan, by Merck Group (3 mentions) Quercetin 3 o glucoside, by Extrasynthese (3 mentions) Procyanidin b2, by Extrasynthese (3 mentions) Procyanidin b3, by Extrasynthese (3 mentions) L proline, by Merck Group (3 mentions) L phenylalanine, by Merck Group (3 mentions) L isoleucine, by Merck Group (3 mentions) L tyrosine, by Merck Group (3 mentions) L leucine, by Merck Group (3 mentions) Caftaric acid, by Biosynth (3 mentions) Millipore milli q system, by Merck Group (3 mentions) Procyanidin b1, by Extrasynthese (3 mentions) Procyanidin c1, by Extrasynthese (3 mentions) E piceid, by Merck Group (3 mentions)

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Trans-coutaric acid (3 citations)

6 protocols using coutaric acid

1

Cultivation of Plant In Vitro Cultures

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Reagents needed for cultivation of in vitro cultures, e.g., MS and SH basal media, agar, PGRs, and sucrose were acquired from Duchefa Farma B.V. (Haarlem, The Netherlands).
Ultrapure water was obtained using Millipore Milli-Q system (Merck Millipore, Molsheim, France). Acetonitrile and methanol were purchased from Thermo Fisher Scientific (Illkirch-Graffenstaden, France). Standard compounds L-leucine, L-isoleucine, L-phenylalanine, L-tyrosine, L-tryptophan, L-proline, citric acid, gallic acid, coutaric acid, trans-resveratrol, cis-resveratrol, E-piceid, catechin, epicatechin, catechin gallate, tyrosinase, and L-DOPA were purchased from Sigma-Aldrich (St. Louis, MO, USA). Rhamnetin, E-ε-viniferin, quercetin 3-O-glucoside, quercetin 3-O-glucuronide, quercetin-3-O-galactoside, procyanidin B1, procyanidin B2, procyanidin B3, and procyanidin C1 were obtained from ExtraSynthèse (Genay, France); caftaric acid was delivered by Carbosynth (Compton, Berkshire, UK), while E-ε-viniferin, Z/E-vitisin B, ampelopsin A, and hopeaphenol were obtained by previous extraction from grape stems [50 (link)].
Sharafan M., Malinowska M.A., Kubicz M., Kubica P., Gémin M.P., Abdallah C., Ferrier M., Hano C., Giglioli-Guivarc’h N., Sikora E., Lanoue A, & Szopa A. (2023). Shoot Cultures of Vitis vinifera (Vine Grape) Different Cultivars as a Promising Innovative Cosmetic Raw Material—Phytochemical Profiling, Antioxidant Potential, and Whitening Activity. Molecules, 28(19), 6868.
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2

Cultivation of Plant In Vitro Cultures

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Reagents needed for cultivation of in vitro cultures, e.g., MS and SH basal media, agar, PGRs, and sucrose were acquired from Duchefa Farma B.V. (Haarlem, The Netherlands).
Ultrapure water was obtained using Millipore Milli-Q system (Merck Millipore, Molsheim, France). Acetonitrile and methanol were purchased from Thermo Fisher Scientific (Illkirch-Graffenstaden, France). Standard compounds L-leucine, L-isoleucine, L-phenylalanine, L-tyrosine, L-tryptophan, L-proline, citric acid, gallic acid, coutaric acid, trans-resveratrol, cis-resveratrol, E-piceid, catechin, epicatechin, catechin gallate, tyrosinase, and L-DOPA were purchased from Sigma-Aldrich (St. Louis, MO, USA). Rhamnetin, E-ε-viniferin, quercetin 3-O-glucoside, quercetin 3-O-glucuronide, quercetin-3-O-galactoside, procyanidin B1, procyanidin B2, procyanidin B3, and procyanidin C1 were obtained from ExtraSynthèse (Genay, France); caftaric acid was delivered by Carbosynth (Compton, Berkshire, UK), while E-ε-viniferin, Z/E-vitisin B, ampelopsin A, and hopeaphenol were obtained by previous extraction from grape stems [50 (link)].
Sharafan M., Malinowska M.A., Kubicz M., Kubica P., Gémin M.P., Abdallah C., Ferrier M., Hano C., Giglioli-Guivarc’h N., Sikora E., Lanoue A, & Szopa A. (2023). Shoot Cultures of Vitis vinifera (Vine Grape) Different Cultivars as a Promising Innovative Cosmetic Raw Material—Phytochemical Profiling, Antioxidant Potential, and Whitening Activity. Molecules, 28(19), 6868.
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3

Polyphenol Fingerprinting of Samples

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Reagents were acquired from various suppliers: authentic standards of oenin (Malvidin-3-O-glucoside), rutin (quercetin 3-O-rutinoside), chlorogenic acid (5-caffeoylquinic acid) from Extrasynthèse (Genay, France); gallic acid, caffeic acid, caftaric acid, coutaric acid, catechin, epicatechin, quercetin-3-glucoside, Folin-Ciocalteu phenol reagent, Trolox [(S)-(−)-6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid], acetonitrile, formic acid, ethanol, (all HPLC grade) from Sigma-Aldrich (St. Louis, MO, USA). Milli-Q water (Merck Millipore, Darmstadt, Germany) was used for the preparation of reagents and antioxidant assays.
Gerardi C., Pinto L., Baruzzi F, & Giovinazzo G. (2021). Comparison of Antibacterial and Antioxidant Properties of Red (cv. Negramaro) and White (cv. Fiano) Skin Pomace Extracts. Molecules, 26(19), 5918.
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4

Phenolic Standards and Analytical Methods

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Phenolic standards (gallic acid (≥98%), (+)-catechin (≥99%), (-)-epicatechin (≥98%), caffeic acid (≥98%), coutaric acid (≥90%), quercetin (≥95%), and myricetin glycosides (≥99%)) were obtained from Sigma Chemical Co. (St. Louis, MO, USA). Keracyanin chloride (≥98%) were obtained from Sigma Chemical Co. as the anthocyanin standard. For HPLC analysis, phosphoric acid, 85 wt.% in H2O were obtained from Sigma Chemical Co. TPTZ (2,4,6-tripyridyl-s-triazine), and FeCl3·6H2O used for the FRAP assay were obtained from Thermo Fisher Scientific Inc. (Waltham, MA, USA). All solvents used in this study were HPLC grade.
Dou F., Rai R, & Nitin N. (2022). Lactic Acid Bacteria Simultaneously Encapsulate Diverse Bioactive Compounds from a Fruit Extract and Enhance Thermal Stability. Molecules, 27(18), 5821.
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5

Characterization of Phenolic Compounds

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Acetonitrile and methanol were purchased from Thermo Fisher Scientific (France). A Millipore Milli-Q system (Merck Millipore, Molsheim, France) provided ultrapure water. L-leucine, L-isoleucine, L-phenylalanine, L-tyrosine, L-tryptophan, L-proline, citric acid, E-resveratrol, E-piceatannol, catechin, epicatechin, coutaric acid, fertaric acid, E-piceid, kaempferol 3-O-glucoside, and kaempferol 3-O-glucuronide were obtained from Sigma-Aldrich (St. Louis, MO, USA). Caftaric acid was purchased from Carbosynth (Compton, Berkshire, UK). Rhamnetin, E-ε-viniferin, kaempferol 3-O-rutinoside, quercetin 3-O-glucoside, quercetin 3-O-glucuronide, myricetin 3-O-glucoside, procyanidin B1, procyanidin B2, procyanidin B3, procyanidin C1, and kaempferol 3-O-rutinoside were purchased from Extrasynthèse (Genay, France). Pallidol and E-δ-viniferin were graciously provided by Dr. Mary-Lorène Goddard (EA-3991, Université de Haute-Alsace, Colmar, France). E-miyabenol C was obtained from Ambinter (Paris, France).
Billet K., Malinowska M.A., Munsch T., Unlubayir M., Adler S., Delanoue G, & Lanoue A. (2020). Semi-Targeted Metabolomics to Validate Biomarkers of Grape Downy Mildew Infection Under Field Conditions. Plants, 9(8), 1008.
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6

Quantification of Phenolic Compounds

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Pure phenolic compound standards (caffeic acid, caftaric acid, catechin, coutaric acid, ellagic acid, epicatechin, ethyl gallate, fertaric acid, ferulic acid, gallic acid, kaempferol, kaempferol-3-O-glucoside, kaempferol-3-O-rutinoside, myricetin, myricetin-3-O-rhamnoside, p-coumaric acid, p-OH-benzoic acid, procyanidin B1, procyanidin B2, protocatechuic acid, quercetin, quercetin-3-O-rutinoside, salicylic acid, syringic acid, t-resveratrol, t-piceid and vallinic acid) were purchased from Sigma-Aldrich Chemical Co. (St.
Louis, MO, USA). Anthocyanin standards (cyanidin chloride, delphinidin chloride, malvidin chloride, pelargonidin chloride, peonidin chloride and petunidin chloride) and pelargonidin-3-O-glucoside were obtained from Extrasynthese (Genay, France). Unless otherwise stated, all other chemicals and reagents were obtained from Sigma-Aldrich Chemical Co. (St. Louis, MO, USA), Panreac (Barcelona, Spain) or Fisher Scientific (Loughborough, UK).
Del Pino-García R., González-SanJosé M.L., Rivero-Pérez M.D., García-Lomillo J, & Muñiz P. (2017). The effects of heat treatment on the phenolic composition and antioxidant capacity of red wine pomace seasonings. Food chemistry, 221.
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