Tms 4

Manufactured by Tomey

Sourced in Japan

The TMS-4 is a laboratory equipment designed for precise measurement and analysis. It is capable of performing a range of tasks, but a detailed description of its core function cannot be provided while maintaining an unbiased and factual approach without extrapolation.

Automatically generated - may contain errors

Lab products found in correlation

Orbscan 2, by Bausch & Lomb (2 mentions) Iolmaster 500, by Zeiss (1 mentions) Tx 20, by Canon (1 mentions) Full auto tonometer tx f, by Canon (1 mentions) Iol master, by Zeiss (1 mentions) Al 3000, by Tomey (1 mentions) Visante oct, by Zeiss (1 mentions) Levofloxacin, by Santen (1 mentions) Visante, by Zeiss (1 mentions) Iolmaster 700, by Zeiss (1 mentions) Wavelight allegro topolyzer vario, by Alcon (1 mentions)

13 protocols using tms 4

Photorefractive Surgery Eligibility Assessment

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Patients who were included in the study were candidates for photorefractive surgery aged between 18 to 40 years; had stable myopic refraction for at least 12 months; had no history of systemic disease, autoimmune disease, or immunosuppressive therapy; were not pregnant or lactating; were not using topical ophthalmic medications; and had no contraindication for PRK. Patients who had unstable refraction after surgery or were lost to follow up were excluded. Soft contact lens usage was ceased at least two weeks prior to surgery. The study protocol was approved by our University Ethics Committee, and written informed consent was obtained from all participants.
Complete eye exam, manifest refraction, cyclorefraction, intraocular pressure (IOP) measurement, dilated fundus examination, measurement of corneal curvature by Javal manual keratometer (Haag-Streit, Switzerland), Orbscan II (Bausch & Lomb, Rochester, NY), Galilei Dual Scheimpflug Analyzer (Ziemer Ophthalmic Systems, Switzerland), Tomey TMS-4 (Tomey, Japan), EyeSys 2000 Corneal Analysis System (EyeSys Vision, Houston, TX), and pachymetry (Nidek, Japan) were performed for all patients preoperatively and six months post-PRK after stability of refraction.

Baradaran-Rafii A., Fekri S., Rezaie M., Salehi-Rad S., Moradi A., Motevasseli T, & Kalantarion M. (2017). Accuracy of Different Topographic Instruments in Calculating Corneal Power after Myopic Photorefractive Keratectomy. Journal of Ophthalmic & Vision Research, 12(3), 254-259.

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Comprehensive Ocular Biometry Measurements

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The detailed measurement methods and instruments have been described in our previous study [23 (link)]. The baseline spherical equivalent refraction (SER) was documented following the administration of cycloplegia. Cycloplegia was induced through the administration of one drop of 1% tropicamide (compound tropicamide eye drops, Shenyang Sinqi, sinqi.com) into each eye, with four repetitions at 5-min interval. A minimum resting period of 20 min was observed prior to achieving cycloplegia. The measurements of keratometry (K), encompassing flat keratometry (Flat K), steep keratometry (Steep K), corneal astigmatism (CA) (Tomey TMS-4, tomey.com), axial length (AL), anterior chamber depth (ACD) (ZEISS IOL Master 500, zeiss.com), and intraocular pressure (IOP) (Canon TX-20, Canon Medical Systems, eu.medical.canon), were conducted. All participants underwent assessment utilizing the specified instruments to determine the aforementioned parameters.

Chen X., Yang B., Wang X., Ma W, & Liu L. (2023). The alterations in ocular biometric parameters following short-term discontinuation of long-term orthokeratology and prior to subsequent lens fitting: a preliminary study. Annals of Medicine, 55(2), 2282745.

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Keratoconus Diagnosis Protocol

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Two cornea specialists diagnosed keratoconus through slit lamp microscopy and corneal topography (TMS-4, TOMEY, Nagoya, Japan). Keratoconus signs found in both slit lamp microscopy and corneal topography were classified as keratoconus, while signs found only in corneal topography were classified as suspected keratoconus. Forme fruste keratoconus was defined as an eye with normal corneal topography in the contralateral eye of the keratoconus. In this study, only keratoconus and suspected keratoconus were included in the keratoconus group. The severity of keratoconus was based on the Amsler–Krumeich classification. This study was approved by the Ethics Committee of Nagoya Eye Clinic (UMIN ID: 000036372). The study was conducted in accordance with the tenets of the Declaration of Helsinki. Because this was a retrospective study, an opt-out method for obtaining consent was approved by the ethics committee.

Kojima T., Isogai N., Nishida T., Nakamura T, & Ichikawa K. (2021). Screening of Keratoconus Using Autokeratometer and Keratometer Keratoconus Index. Diagnostics, 11(11), 2120.

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Preoperative Ocular Biometrics Analysis

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The medical files of patients were reviewed, demographic and preoperative data were collected including: age, gender, sphere, refractive astigmatism, flat K, steep K, corneal astigmatism, intraocular pressure, and central corneal thickness (CCT). Manifest and cycloplegic refraction were assessed by the same optometrist. Corneal curvature was obtained by corneal topography (Tomey, TMS-4, Japan), IOP was measured with a non-contact tonometer (Canon Full Auto Tonometer TX-F; Canon, Inc., Tokyo, Japan). CCT was measured with Sonomed Micropach 200P + (Sonomed, New Hyde Park, NY, USA). CCT, Manifest and cycloplegic refraction and corneal topography were performed by two experienced operators (L.S, YM. J). Date obtained from the right and left eye of a subject are often correlated, so the date of the right eye in this study was used for statistical analysis (12 ).
Refractive data were converted to minus cylinder form during analysis. The axis of astigmatism was defined for 180° ± 30° as WTR, for 90° ± 30° as ATR, whereas 45° ± 15° and 135° ± 15° were regarded as oblique astigmatism.

Yang S., Jiang Y., Cui G, & Li Y. (2022). Age- and gender-related characteristics of astigmatism in a myopic population. Frontiers in Medicine, 9, 1011743.

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Comprehensive Preoperative Ocular Evaluation

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Preoperative examination included uncorrected distance visual acuity (UDVA) and corrected distance visual acuity (CDVA), manifest refraction, corneal thickness (Orbscan II; Bausch & Lomb, Rochester, NY, USA), corneal topography (TMS-4; Tomey, Nagoya, Japan), and corneal refractive power.

Kataoka T., Nishida T., Murata A., Ito M., Isogai N., Horai R., Kojima T., Yoshida Y, & Nakamura T. (2018). Control-matched comparison of refractive and visual outcomes between small incision lenticule extraction and femtosecond laser-assisted LASIK. Clinical Ophthalmology (Auckland, N.Z.), 12, 865-873.

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Preoperative Assessments for Refractive Surgery

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Preoperative assessment included examinations from IOL-Master (version 5.5, Carl Zeiss Meditec, Inc., Jena, Germany, keratometric index: 1.3375), TMS-4 (Topographic Modeling System, Tomey, Inc., Nagoya, Japan, keratometric index: 1.3375), and AL-3000 (Bio & Pachy Meter AL-3000, Tomey, Inc., Nagoya, Japan). The examination of AL-3000 was performed last to avoid corneal indentation and maintain the integrity of the corneal epithelium when other preoperative measurements were gauged. The sequence between IOL-Master and TMS-4 was random. Patients were asked to blink just before measurements were taken. Pupil sizes during preoperative assessments were normal [12 (link)]. All preoperative examinations were carried out by the first author, who was trained and qualified according to the manufacturer’s recommendation. The follow-up points were 1 week, 1 month, and 3 months after the surgery when postoperative assessments using slit-lamp biomicroscopy, auto refractometer, streak retinoscopy, and subjective manifest refraction were implemented. The data in this article were from the 3-month point.

Wu Y., Liu S, & Liao R. (2017). Prediction accuracy of intraocular lens power calculation methods after laser refractive surgery. BMC Ophthalmology, 17, 44.

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Long-Term Corneal Evaluation Post-Op

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Three patients (3 eyes) were monitored for at least 12 months and were assessed using slit-lamp microscopy, corneal topography (Tomey, TMS-4, Japan), optical coherence tomography (Visante OCT, Carl Zeiss Meditec, Dublin, USA) and best corrected visual acuity (BCVA). Postoperative complications throughout the study period were recorded.

Jiang Y., Li Y., Yang S, & Lu T.C. (2017). Tuck-in Lamellar keratoplasty with an lenticule obtained by small incision lenticule extraction for treatment of Post- LASIK Ectasia. Scientific Reports, 7, 17806.

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Comprehensive preoperative ocular assessment

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Before surgery, a comprehensive ophthalmic examination was performed, including uncorrected and best corrected visual acuity (BCVA), corneal topography (Tomey TMS-4, Nagoya, Japan), refraction, intraocular pressure, slit-lamp biomicroscopy, and dilated fundus examination. Surface asymmetry index (SAI) and surface regularity index (SRI) were obtained from the topography. Anterior slit-lamp microscopic photography was taken for each patient. Additionally, 0.3% levofloxacin (Santen, Japan) eye drops were prescribed four times daily for 3 days before surgery.

Chen D., Liu X., Long Q., Wang Z, & Li Y. (2019). Effects of excimer laser phototherapeutic keratectomy in limbal-conjunctival autograft transplantation for recurrent pterygium: a retrospective case control study. BMC Ophthalmology, 19, 238.

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Comprehensive Preoperative Ophthalmic Evaluation

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Preoperatively, all patients underwent comprehensive ophthalmic examinations, including corrected distance visual acuity, intraocular pressure, anterior segment slit-lamp examination, fundus examination, and cycloplegic refraction. Corneal tomography (TMS-4; Tomey Corporation, Aichi, Japan) was used to measure the flattest meridian keratometry (Kf) and steepest meridian keratometry (Ks). Partial coherence interferometry (IOL Master 700; Carl Zeiss Meditec, Jena, Germany) was used to assess axial length (AL; mm), central corneal thickness (CCT; µm), WTW distance (mm), and lens thickness (LT; mm). Anterior segment optical coherence tomography (ASOCT, Visante; Carl Zeiss Meditec) was used to obtain ACD (mm), anterior chamber width (ACW; mm), angle-to angle (ATA) distance (mm), crystalline lens rise (CLR; µm), pupil distance (PD; mm), angle opening distance (AOD; 500 and 700 mm), trabecular iris space area (TISA; 500 and 700 mm²), and anterior chamber angle (ACA) (Figs. 2A, 2B). The inferior surface curvature of the iris was obtained by PyQt5 framework development of annotation tools (Fig. 2C). Postoperatively, we measured the central vault at 1 week using the same ASOCT. The same examinations were performed by the same experienced physician under indoor natural light. Three measurements were taken for the average value.

Di Y., Fang H., Luo Y., Li Y, & Xu Y. (2024). Predicting Implantable Collamer Lens Vault Using Machine Learning Based on Various Preoperative Biometric Factors. Translational Vision Science & Technology, 13(1), 8.

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Comprehensive Ophthalmic Examination Protocol

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Clinical examinations included measurements of the best corrected visual acuity (BCVA), refractive error, biomicroscopic examination, and corneal imaging using Tomey topography (TMS-4, Tomey, Nishi-Ku, Japan) and Pentacam (WaveLight Allegro Topolyzer Vario, Alcon, United States). Funduscopy was also conducted by an indirect binocular ophthalmoscope through dilated pupil using a 78D lens.

Mohammad-Rabei H., Ramin S., Lotfi S., Sabbaghi H., Karimian F., Abdi S., Hasan Shahriari M., Kheiri B., Sheibani K, & Ali Javadi M. (2023). Risk Factors Associated with Keratoconus in an Iranian Population. Journal of Ophthalmic & Vision Research, 18(1), 15-23.

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