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Magnetom verio 3.0 t mri scanner

Manufactured by Siemens
Sourced in Germany

The Magnetom Verio 3.0 T MRI scanner is a magnetic resonance imaging system produced by Siemens. It operates at a field strength of 3.0 Tesla and is designed to generate high-quality images of the body's internal structures.

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7 protocols using magnetom verio 3.0 t mri scanner

1

Multimodal MRI Protocol for Glioma Evaluation

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Conventional MRI and 1H-MRS scans were performed at 3.0 T using a Siemens Magnetom Verio 3.0 T MRI scanner (Siemens Medical Solutions, Erlangen, Germany). The protocol for MRI included T1-weighted imaging (repetition time [TR], 1.90 ms; echo time [TE], 2.93 ms; matrix size, 256×215; slice thickness, 1 mm; field of view [FOV], 250×219 mm2; acquisition averages 1) and T2-weighted fluid-attenuated inversion recovery (T2-FLAIR) sequence (TR, 9.00 ms; TE, 96 ms; TI, 2.5 ms; slice thickness, 2 mm; matrix size, 256×160).
Regular brain MRI and contrast-enhanced scans were followed by 1H-MRS imaging.
MRS imaging was acquired for the gliomas (including areas of necrosis and edema) and contralateral normal brain tissues using 3D multivoxel pointed-resolved spectroscopy sequence (PRESS; TR, 1.70 ms; TE, 135 ms; slice thickness, 15 mm; phase encoding, 16×16×16; FOV, 120×120 mm2). The voxel size was 10×10×10 mm3.
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2

Structural Brain Imaging MRI Preprocessing

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All participants were images on the same Magnetom Verio 3.0-T MRI scanner (Siemens, Munich, Germany) at Shanghai Mental Health Center. The T1-weighted sequence was scanned with the parameters of repetition time = 2530 ms, echo time = 2.34 ms, inversion time = 1100 ms, flip angle = 7°, field of view = 256 mm, with 192 1-mm slices (no gap).
Data were processed using Statistical Parametric Mapping (SPM8) (www.fil.ion.ucl.ac.uk/spm) and voxel-based morphometry (VBM8) toolbox with default parameters (http://dbm.neuro.uni-jena.de/vbm/) in Matlab 2012a. Structural T1-weighted MR images were bias-corrected and segmented into gray matter (GM), white matter, and cerebrospinal fluid. Images of GM and white matter were normalized spatially to the standard Montreal Neurological Institute template and modulated to account for the volume changes caused by normalization. The modulated GM images were smoothed further with a Gaussian kernel of 8-mm full-width-at-half maximum.
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3

Resting-State fMRI and Structural MRI Acquisition Protocol

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All participants were scanned at the Brain & Mind Research Center, Nagoya University, using a Siemens Magnetom Verio 3.0 T MRI scanner with a 32-channel head coil (Siemens, Erlangen, Germany). For each participant, high-resolution T1-weighted (T1w) MRI and resting-state fMRI data were obtained. The T1w images were acquired using a three-dimensional magnetization prepared rapid acquisition gradient echo (MPRAGE, Siemens, Erlangen, Germany) sequence (Mugler and Brookeman, 1990 (link)) with the following imaging parameters: repetition time (TR) = 2500 ms, echo time (TE) = 2.48 ms, inversion time = 900 ms, flip angle (FA) = 8 degrees, field of view (FOV) = 256, 256 × 256 matrix dimension, 192 sagittal slices with 1-mm thickness, in-plane voxel resolution of 1.0 × 1.0 mm2, and total scan time of 5 min and 49 s. For the resting-state fMRI data, an ascending gradient-echo echo-planar imaging sequence was used, with the following parameters: TR = 2.5 s, TE = 30 ms, FOV = 192 mm, 64 × 64 matrix dimension, 39 transverse slices with a 0.5 mm inter-slice interval and 3-mm thickness, FA = 80 degrees, and total scan time of 8 min and 15 s. All participants were instructed to close their eyes but stay awake during the scan.
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4

Resting-state fMRI and T1-weighted Imaging Protocol

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MR imaging was acquired with a Siemens MAGNETOM Verio 3.0 T MRI scanner using a 12-channel head coil at the National Institute of Radiological Sciences. RsfMRI acquisition was performed with a gradient-recalled echo-planar imaging sequence (TR = 2000 ms, TE = 25 ms, flip angle = 75°, matrix = 64 × 64, thickness = 3.4 mm, voxel size = 3.44 × 3.44 × 3.74 mm3). The number of slices in each volume was 33, and 215 volumes were scanned in 7 min 10 s. All participants were instructed to keep still and to focus on the crosshairs projected onto a screen during scanning. T1-weighted imaging was acquired with a 3D magnetization-prepared rapid acquisition gradient-echo sequence (MPRAGE, TR = 2,300 ms, TE = 2.46 ms, flip angle = 9°, TI = 900 ms, matrix = 256 × 256, thickness = 1.0 mm, voxel size = 1.00 × 1.00 × 0.98 mm3).
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5

Functional MRI Acquisition Protocol

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Data collection: All data were collected using a Siemens MAGNETOM Verio 3.0 T MRI scanner from Germany. During the scanning process, patients were in a supine position, with their eyes closed and head immobilized. They wore noise-canceling earplugs, maintained calm breathing, remained awake, and minimized body movement.
EPI scan parameters: Repetition time (TR) = 3,000 ms; Echo time (TE) = 30 ms; Flip angle = 90°; Slice thickness = 3 mm; Number of slices = 43; Matrix size = 64 × 64; Field of view (FOV) = 230 mm × 230 mm; Voxel size = 3.6 mm × 3.6 mm × 3 mm; Total of 200 time points were collected.
T1 sequence scan parameters: TR = 1900 ms; Inversion time = 900 ms; TE = 2.93 ms; Flip angle = 9°; FOV = 256 mm × 256 mm; Slice thickness = 1 mm; Matrix size = 256 × 256.
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6

Multimodal Neuroimaging Protocol for Consciousness Assessment

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A Siemens Magnetom Verio 3.0 T MRI scanner (Siemens, German) with a standard head coil was used to scan the patients in the Department of Radiology of Huashan Hospital, Shanghai, China. The gradient-echo EPI images of the whole brain parameters were set as follows: 33 slices, repetition time/echo time [TR/TE] = 2,000/35 ms, slice thickness = 4 mm, field of view = 256 mm, flip angle = 90°, image matrix: 128 × 128). In total, 200 scans (406 seconds) were acquired in the resting run. In addition, high-resolution anatomical images were acquired for all subjects. T1-weighted magnetization-prepared rapid-gradient echo (MPRAGE) sequences were acquired through the sagittal plane with the following parameters: TR = 2300 ms; TE = 2.98 ms; TI = 900 ms; flip angle = 9°; matrix size = 256 × 240; slice number = 176; field-of-view (FOV) = 256 × 240 mm; acquisition averages = 1; scanning time = 301s. Patients’ CT scans were collected for detecting and identifying cerebral lesions. If the quality of the fMRI data were not satisfactory, such as being confounded by excessive head movements, a scan was performed again on a subsequent day.
All subjects’ MRI scans were acquired under resting states. For each patient, consciousness assessment were performed according to the standardized Glasgow Coma Scale (GCS) and CRS-R24 (link).
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7

Diffusion Tensor Imaging Protocol

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A Magnetom Verio 3.0 T MRI scanner (Siemens Medical Solutions, Erlangen, Germany) equipped with a 32-channel head coil was used to obtain MRI scans of all subjects. The scanning parameters were as follows: repetition time (TR)/echo time (TE) = 10,300/95 ms, field of view (FOV) = 256 × 256 mm2, matrix = 128 × 128, voxel size = 2.0 × 2.0 × 2.0 mm3, slice thickness = 2 mm, number of directions = 64, b = 1000 s/mm2. DTI data preprocessing and atlas-based analysis (ABA) were carried out with FSL 5.0.9 (https://fsl.fmrib.ox.ac.uk/) and PANDA (Pipeline for Analysing braiN Diffusion imAges, http://www.nitrc.org/projects/panda/). The preprocessing steps included format conversion, mask generation and cropping, head motion and eddy correction, and spatial registration. Details for data acquisition and preprocessing are presented in Additional file 1.
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