1 ethyl 3 3 dimethylamino propyl carbodimide edc

Manufactured by Merck Group

Sourced in China

1-ethyl-3-(3-(dimethylamino)-propyl)carbodimide (EDC) is a carbodiimide compound commonly used as a coupling agent in various chemical reactions. It is a colorless, crystalline solid with the molecular formula C8H17N3. EDC is known for its ability to facilitate the formation of amide bonds between carboxylic acids and primary amines.

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Lab products found in correlation

N hydroxysulfosuccinimide sulfo nhs, by Merck Group (2 mentions) Trifluoroacetic acid tfa, by Sinopharm (1 mentions) C18pmh, by Merck Group (1 mentions) Dimethyl sulfoxide (dmso), by Sinopharm (1 mentions) Dimethyl sulfoxide (dmso), by Frontier Scientific (1 mentions) Meso tetra 4 carboxyphenyl porphyrin mtcpp, by Frontier Scientific (1 mentions)

3 protocols using 1 ethyl 3 3 dimethylamino propyl carbodimide edc

Chemoselective Bioconjugation of Chlorin e6

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Poly (maleic anhydride-alt-1-octadecene) (C₁₈PMH), 1-ethyl-3-(3-(dimethylamino) -propyl)carbodimide (EDC), and Sulfo-NHS (N-hydroxysulfosuccinimide) were obtained from Sigma-Aldrich. Chlorine e6 (Ce 6) were from J&K Chemical Co. Dimethyl sulfoxide (DMSO) and trifluoroacetic acid (TFA) were obtained from Sinopharm Chemical Reagent Co. mPEG-NH₂ (5k), and Boc-PEG-NH₂(3350) were obtained from Biomatrik Co., Ltd (Jiaxing, China). Deionized water used in our experiments was obtained from a Milli-Q water system.

Cheng L., Kamkaew A., Sun H., Jiang D., Valdovinos H.F., Gong H., England C.G., Goel S., Barnhart T.E, & Cai W. (2016). Dual-Modality Positron Emission Tomography/Optical Image-Guided Photodynamic Cancer Therapy with Chlorin e6-Containing Nanomicelles. ACS nano, 10(8), 7721-7730.

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Synthesis of PLGA-Cisplatin Nanoparticles

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PLGA ([η] = 0.32–0.44 dL/g; 50:50) and CDDP was purchased from Sigma-Aldrich (China). Cisplatin, PEG-diamine (Mn ~ 2000) was purchased from Laysan Bio Inc (Arab, AL). 1-ethyl-3 (3-dimethylaminopropyl) carbodimide (EDC) was purchased from Sigma Aldrich, China. All other chemicals were of reagent grade and used without further purifications.

Wang Z.Q., Liu K., Huo Z.J., Li X.C., Wang M., Liu P., Pang B, & Wang S.J. (2015). A cell-targeted chemotherapeutic nanomedicine strategy for oral squamous cell carcinoma therapy. Journal of Nanobiotechnology, 13, 63.

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Porphyrin-PEG Conjugates Synthesis

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Meso-tetra(4-carboxyphenyl)porphyrin (mTCPP) and Dimethyl sulfoxide (DMSO) were obtained from Frontier Scientific, Inc. (Logan, UT, USA). Polyethylene glycol (PEG)_2K, PEG_5K, PEG_10K, and PEG_30K were obtained from Biomatrik Co., Ltd. (Jiaxing, China) with the molecular weight of 2 kDa, 5 kDa, 10 kDa, and 30 kDa, respectively. 1-ethyl-3-(3-(dimethylamino)-propyl)carbodimide (EDC), and N-hydroxysulfosuccinimide (Sulfo-NHS) were obtained from Sigma-Aldrich. Deionized water used in our experiments was obtained from a Milli-Q water system.

Cheng L., Jiang D., Kamkaew A., Valdovinos H.F., Im H.J., Feng L., England C.G., Goel S., Barnhart T.E., Liu Z, & Cai W. (2017). Renal-Clearable PEGylated Porphyrin Nanoparticles for Image-guided Photodynamic Cancer Therapy. Advanced functional materials, 27(34), 1702928.

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