Quartz sand sio2

AZI, ERY-IE, ERY-OX and CLA were kindly supplied by Pliva (Croatia), while ROX was acquired from Sigma-Aldrich (Germany). The remaining eight target compounds, as well as deuterated azithromycin (AZI-d3) and deuterated clarithromycin (CLA-d3), used as internal standards, were purchased from Toronto Research Chemicals (Canada).
HPLC grade methanol (MeOH) and acetonitrile (ACN) were purchased from BDH Prolabo (UK), acetone from Merck (Germany), anhydrous ammonia solution (7 N in MeOH) from Alfa Aesar (Germany), and ACS grade formic acid, as well as quartz sand (SiO2), from Sigma-Aldrich. Ultrapure water was produced by Elix-Milli-Q system (Millipore, USA). Cellulose filters (type D28), used for pressurized liquid extraction (PLE), were produced by Dionex Corporation (USA) and regenerated cellulose filters (0.45 µm), used for the final extract filtration, by Waters (USA). HPLC column ACE C18 PFP (150 × 3 mm; 3 μm) was purchased from Advanced Chromatography Technologies (UK).

Chloroplatinic acid hexahydrate (H2PtCl6•6H2O; ≥ 37.5% platinum basis), quartz sand (SiO2), and benzene liquid primary standard (L-PS; ≥ 99.8%) were purchased from Sigma-Aldrich (St. Louis, Missouri, USA). Ti3C2 MXene powder (> 98%) was provided by Invisible Co., Ltd. (South Korea). Nitrogen (N2; 99.999%), H2 (99.999%), and air (99.999%) cylinders were supplied by Union Gas Co., Ltd. (South Korea).