DIOA, #D129 SigmaAldrich.Bumetanide, #B3023 Sigma Aldrich.Staurosporine, #sc3510A Santa Cruz Biotechnology.Go6983, #G1918 SigmaAldrich.BAY11-7085, #B3033 APExBio.VU0463271, #4719 Tocris. All inhibitors were applied in Ringer’s solution at concentrations and incubation times shown in the relevant figure legend.
Bay11 7085
Manufactured by Apexbio
Sourced in Colombia
BAY11-7085 is a chemical compound that is used in laboratory research. It functions as an inhibitor of the activation of the nuclear factor-kappa B (NF-κB) signaling pathway. This pathway is involved in the regulation of various cellular processes, including inflammation and immune responses.
Automatically generated - may contain errors
Lab products found in correlation
2 protocols using bay11 7085
1
Signaling Pathway Inhibitors in Ringer's
2
Evaluating Gefitinib, Erlotinib, and Cetuximab Efficacy
Check if the same lab product or an alternative is used in the 5 most similar protocols
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Cells were seeded at a density of 10,000 cells/well in a 96-well plate and allowed to attach for eight hours prior to drug treatment. For viability testing, cells were treated with 5 μM gefitinib (#076091; Matrix Scientific, Columbia, SC), 10 μM erlotinib (#10483; Cayman Chemical; Ann Arbor, MI), or 10 nM cetuximab (#NBP2-75903; Novus Biologicals; Centennial, CO), with or without BAY 11–7085 (#B3033; ApexBio Technology; Houston, TX) at 2 μM or 3.3 μM for 48 hours. DMSO vehicle controls were included. For all treatments the final DMSO concentration was 1%. After 48 hours cell viability was assessed using the MTS assay (Biovision; Milpitas, CA) as previously described [35 (link)]. Viability was calculated by normalizing each cell line to vehicle treatment alone.
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