5 fu s1209

Manufactured by Selleck Chemicals

Sourced in United States

5-FU (S1209) is a chemical compound used in laboratory settings. It functions as an antimetabolite, which means it interferes with the normal function of cellular processes. This product is intended for research purposes only and should be handled with appropriate safety precautions.

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Lab products found in correlation

Dox s1208, by Selleck Chemicals (1 mentions) Sorafenib s7397, by Selleck Chemicals (1 mentions)

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S1209 (2 citations)

2 protocols using 5 fu s1209

Evaluating HCC Drug Sensitivity

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Two 3D-HCC cancer in vitro models (CSM and ASM) were used in drug sensitivity assays to identify changes in drug sensitivity for each model. The drugs most commonly used for HCC were selected. Sorafenib (S7397), Cabozantinib (S1119), Lenvatinib (S1164), Regorafenib (S1178), 5-FU (S1209), and DOX (S1208) were purchased from Selleckchem (Houston, TX, USA). Drugs were dissolved in a stock solution of dimethyl sulfoxide (DMSO, 100 mM).

Lee S.Y., Teng Y., Son M., Ku B., Hwang H.J., Tergaonkar V., Chow P.K., Lee D.W, & Nam D.H. (2021). Three-Dimensional Aggregated Spheroid Model of Hepatocellular Carcinoma Using a 96-Pillar/Well Plate. Molecules, 26(16), 4949.

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Characterization of Cell Signaling Pathways

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Anti-Mouse secondary antibody (7076), CDK2 (2546), CDK4 (12790), CDK6 (3136), CyclinD1 (2978), Akt (4691), p-Akt (4060), p-CHK1 (2348), p-CHK2 (2197), p-BCA1 (9009), Anti-Rabbit (7074), Iκbα (4814), p-Iκbα (2859), p-JNK (4668), p-p65 (3033), p65 (8242), p18(2896), p21 (2947), p27 (3686), p38 (8690), p-p38 (4511), GAPDH (5174), β-Actin (4970), p-ERK (9101) and ERK (4695) were purchased from Cell Signaling Technology (Danvers, MA, USA). Chemical inhibitors SB203580 (S1076), PD98059 (S1177), Bay11-7082 (S2913) were from Selleck (Shanghai, China). Chemotherapeutic agents 5-Fu (S1209) and cisplatin (s1166) were from Selleck.

Ma J., Hu X., Liao C., Xiao H., Zhu Q., Li Y., Liu Z., Tao A., He Z., Xu C, & Zheng K. (2019). Gypenoside L Inhibits Proliferation of Liver and Esophageal Cancer Cells by Inducing Senescence. Molecules, 24(6), 1054.

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