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Lys 3 bombesin

Manufactured by Merck Group
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[Lys]3-bombesin is a synthetic peptide that mimics the structure of the naturally occurring bombesin peptide. It is commonly used in research applications as a reagent for the study of bombesin receptor-mediated cellular processes.

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Lab products found in correlation

Substance p, by Merck Group (2 mentions) Formic acid, by Merck Group (2 mentions) Epr tube, by Wilmad (1 mentions) Agilent tuning mix, by Agilent Technologies (1 mentions) Lc ms grade acetonitrile acn, by Avantor (1 mentions) Low concentration tuning mix, by Agilent Technologies (1 mentions)

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Bombesin (5 citations)

2 protocols using lys 3 bombesin

1

Characterization of Complex 1 by EPR

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Substance P, [Lys]3-bombesin, and formic acid were purchased from Sigma Aldrich Company Ltd., Dorset, UK. Low concentration Agilent tuning mix was purchased from Agilent Technologies (Santa Clara, CA). Complex 1 was synthesised and characterised as described elsewhere.6 (link) EPR tubes were purchased from Wilmad Labglass. The spin trap 5-(diethoxyphosphoryl)-5-methyl-1-pyrroline-N-oxide (DEPMPO) was obtained from Enzo Life Sciences in high purity. Ultra-pure water was obtained from a Milli-Q UV III system (Milli-Q, Hertfordshire, UK).
Wootton C.A., Sanchez-Cano C., Lopez-Clavijo A.F., Shaili E., Barrow M.P., Sadler P.J, & O'Connor P.B. (2018). Sequence-dependent attack on peptides by photoactivated platinum anticancer complexes †Electronic supplementary information (ESI) available: Detailed MS data and discussion of effects of Pt on MS/MS fragmentation, as Scheme S1, Tables S1–S14 and Fig. S1–S10. See DOI: 10.1039/c7sc05135b. Chemical Science, 9(10), 2733-2739.
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2

Synthesis and Characterization of Iridium Anticancer Complexes

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Substance P, [Lys]3-Bombesin, and formic acid were purchased from Sigma Aldrich (St. Louis, MO). LCMS grade Acetonitrile (ACN) was obtained from VWR (Radnor, PA) and used without further purification. Low concentration tuning mix was purchased from Agilent Technologies (Santa Clara, CA) and used as received. The iridium(III) anticancer complexes Ir2+Cl and Ir3+Cl were synthesised and characterised using previous methods. 13 The synthesis of the di-aldehyde derivative (Ir1+Cl) is described in the Supporting Information (SI).
Wootton CA ., Millett AJ ., Lopez-Clavijo AF ., Chiu CKC ., Barrow MP ., Clarkson GJ ., Sadler PJ , & O'Connor PB . (2019). Structural analysis of peptides modified with organo-iridium complexes, opportunities from multi-mode fragmentation. The Analyst, 144(5).
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