The natural products were selected from an assembled compound library from dietary supplements (Cat. No. L6000, purity>95%, TargetMol, Boston, MA, USA; Cat. No. L1400, purity>95%, Selleck Chemicals, Houston, TX, USA). The capsaicin standard (purity>98%) was purchased from TargetMol (Cat. No. T1062). ST-193, F3406-2010, efavirenz and bafilomycin A1 were described previously32 (link). Doxorubicin hydrochloride was purchased from TargetMol (Cat. No. T1020). All compounds were dissolved in dimethyl sulfoxide (DMSO, Cat. No. 34943, Sigma–Aldrich, St. Louis, MO, USA) and stored at −20 °C until use. DMSO (0.1%, v/v) was used as a solvent control in all experiments.
Doxorubicin hydrochloride
Manufactured by Targetmol
Sourced in China
Doxorubicin hydrochloride is a chemotherapeutic agent used in the treatment of various types of cancer. It is a red-orange crystalline powder that is soluble in water and alcohol. The product is intended for research purposes only and its use should be in accordance with relevant regulations and guidelines.
Automatically generated - may contain errors
Lab products found in correlation
2 protocols using doxorubicin hydrochloride
1
Compound Library for Drug Discovery
2
Osteosarcoma Cell Lines and Osteoclastogenesis
Check if the same lab product or an alternative is used in the 5 most similar protocols
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Pictilisib (C23H27N7O3S2; MW, 513.64; purity, ≥99%) Doxorubicin hydrochloride (C27H29NO11*HCl; MW, 579.99; purity, 99.37%), and dimethyl sulfoxide (DMSO) were purchased from TargetMol (Shanghai, China) and stored at −20°C. Four OS cell lines (MG-63, U2OS, Saos2, and 143B) were cultured in Dulbecco’s modified Eagle’s medium (DMEM) supplemented with 10% fetal bovine serum (FBS) and 1% penicillin/streptomycin. Primary BMMs were isolated from C57BL/6 mice and cultured in α-modified Eagle’s medium supplemented with 1% penicillin/streptomycin, 10% FBS, and 30 ng/ml M-CSF at 37°C and 5% CO2 (21 (link)). Recombinant murine M-CSF and RANKL were obtained from R&D Systems (Minneapolis, MN, USA).
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