Histocore peloris 3 premium tissue processing system

Manufactured by Leica Biosystems

Sourced in United States

The HistoCore PELORIS 3 Premium Tissue Processing System is a high-performance tissue processing instrument designed for use in clinical and research laboratories. The system is capable of automated tissue processing and paraffin embedding, providing consistent and reliable results.

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Lab products found in correlation

Benchmark xt, by Roche (1 mentions) Histocore arcadia embedding center, by Leica Biosystems (1 mentions) Histocoreautocut automated rotary microtome, by Leica Biosystems (1 mentions)

2 protocols using histocore peloris 3 premium tissue processing system

Breast Cancer Biomarker Profiling

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Preoperative CNB specimen was fixed by 10% formalin for 2 hours. Postoperative SS was serially sectioned into thin slices and fixed by 10% formalin for at least 5 hours. CNB was submitted entirely and SS was submitted at least 2 representative sections of tumor for tissue processing (HistoCore PELORIS 3 Premium Tissue Processing System, Leica Biosystems, IL, USA).
Serial 4-µm-thick paraffin-embedded sections from CNB and SS were stained for ER (SP1, Ventana Medical System, Tucson, AZ, USA), PR (1E2, Ventana Medical System, Tucson, AZ, USA) and HER2/neu (4B5, Ventana Medical Systems) by using an automated immune stainer (BenchMark XT; Ventana Medical System). Silver in situ hybridization was performed using HER2/CEP17 dual-probe (Ventana Medical Systems) through an automated stainer (BenchMark XT; Ventana Medical System).

Park J.H., Kim H.Y., Jung Y.J., Kim D.I., Kim J.Y, & Paik H.J. (2019). Identifying breast cancer patients who require a double-check of preoperative core needle biopsy and postoperative surgical specimens to determine the molecular subtype of their tumor. Annals of Surgical Treatment and Research, 97(5), 223-229.

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Histological Analysis of Liver Tissue

Cited 2 times

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The livers of controls and TAA-treated rats were removed and fixed in 10% formalin, regularly subjected to paraffin sections, and stained with hematoxylin and eosin (H and E). Briefly, after gradient dehydration with various concentrations of alcohol in an automatic tissue dehydrator (HistoCore PELORIS 3 Premium Tissue Processing System, Leica Biosystems Inc., Buffalo Grove, IL, USA), the liver of each animal was embedded in paraffin blocks (using HistoCore Arcadia Embedding Center, Leica Biosystems Inc., Buffalo Grove, IL, USA). The liver tissue was then cut into 10 µm thin slices via an ultra-thin semiautomatic microtome (Histocoreautocut automated rotary microtome, Leica Biosystems Inc., Buffalo Grove, IL, USA), and adhered to the slides. Then, the slides were stained with H and E, and the morphological changes were evaluated using a microscope (Olympus VS120 Automated Slide Scanner, Olympus, Pittsburgh, PA, USA) [25 (link),26 (link)].

El-Mansoury B., Smimih K., El Khiat A., Draoui A., Aimrane A., Chatoui R., Ferssiwi A., Bitar A., Gamrani H., Jayakumar A.R, & El Hiba O. (2024). Short Working Memory Impairment Associated with Hippocampal Microglia Activation in Chronic Hepatic Encephalopathy. Metabolites, 14(4), 193.

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