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Tse metabolic chambers

Manufactured by TSE Systems
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Sourced in Germany

TSE metabolic chambers are specialized equipment used to measure the metabolic parameters of small laboratory animals, such as rodents. The chambers provide a controlled environment to monitor and record various physiological data, including oxygen consumption, carbon dioxide production, and energy expenditure.

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Lab products found in correlation

Mq10 nmr analyzer, by Bruker (4 mentions)

6 protocols using tse metabolic chambers

1

Indirect Calorimetry of THC Effects

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Indirect calorimetry was performed at week 16 (after THC treatment for 8 weeks) using TSE metabolic chambers (TSE Labmaster System, Bad Homburg, Germany). Mice were individually housed in the metabolic cages and acclimatized for 24 h prior to the beginning of an additional 24 h of hourly recording of metabolic parameters. The parameters include food consumption, water intake, the volume of O2 (VO2), the volume of CO2 (VCO2), respiratory exchange ratio (RER = VO2/VCO2) and heat production (kcal/h) were recorded and calculated by TSE software.
Tsai Y.Z., Tsai M.L., Hsu L.Y., Ho C.T, & Lai C.S. (2021). Tetrahydrocurcumin Upregulates the Adiponectin-AdipoR Pathway and Improves Insulin Signaling and Pancreatic β-Cell Function in High-Fat Diet/Streptozotocin-Induced Diabetic Obese Mice. Nutrients, 13(12), 4552.
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2

Measuring Metabolic Rates via NMR

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Metabolic measurements were obtained continuously using TSE metabolic chambers (TSE Labmaster System, Germany) in an open circuit indirect calorimetry system. Data was normalized to lean body mass as determined using a Bruker MQ10 NMR analyzer.
Morley T.S., Xia J.Y, & Scherer P.E. (2015). Selective enhancement of insulin sensitivity in the mature adipocyte is sufficient for systemic metabolic improvements. Nature Communications, 6, 7906.
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3

Metabolic Response to β3 Agonist

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Indirect calorimetry analysis was achieved in TSE metabolic chambers (TSE Systems, Chesterfield, MO). Male mice were individually housed in chamber with ad libitum access to water and regular chow diet under 12-hour light/dark cycle. After acclimation in chambers for 1 day, the mice were injected with 1 mg/kg body weight of β3 agonist CL-316,243. Metabolic profiles, including O2 consumption (mL/kg/h), CO2 generation (mL/kg/h), heat generation (kcal/kg/h), respiratory exchange rate (RER; VCO2/VO2), food intake (g), and movements (counts), were continuously recorded before and after injection. The data of 3-hour period before and after injection were used for statistical analysis.
Li X., Yang L., Mao Z., Pan X., Zhao Y., Gu X., Eckel-Mahan K., Zuo Z., Tong Q., Hartig S.M., Cheng X., Du G., Moore D.D., Bellen H.J., Sesaki H, & Sun K. (2020). Novel role of dynamin-related-protein 1 in dynamics of ER-lipid droplets in adipose tissue. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 34(6), 8265-8282.
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4

Metabolic Measurements via Indirect Calorimetry

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Metabolic measurements were obtained continuously using TSE metabolic chambers (TSE Labmaster System, Germany) in an open-circuit indirect calorimetry system. Data were normalized to lean body mass as determined using a Bruker MQ10 NMR analyzer.
Morley T.S., Xia J.Y, & Scherer P.E. (2015). Selective enhancement of insulin sensitivity in the mature adipocyte is sufficient for systemic metabolic improvements. Nature Communications, 6, 7906.
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5

Continuous Metabolic Monitoring in Mice

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Metabolic measurements were obtained continuously using TSE metabolic chambers (TSE Labmaster System, Germany) in an open-circuit indirect calorimetry system. Studies were performed from days 4 to 6 after implanting osmotic pumps. Data were normalized to lean body mass as determined using a Bruker MQ10 NMR analyzer.
Sharma A.X., Quittner-Strom E.B., Lee Y., Johnson J.A., Martin S.A., Yu X., Li J., Lu J., Cai Z., Chen S., Wang M.Y., Zhang Y., Pearson M.J., Dorn A.C., McDonald J.G., Gordillo R., Yan H., Thai D., Wang Z.V., Unger R.H, & Holland W.L. (2018). Glucagon Receptor Antagonism Improves Glucose Metabolism and Cardiac Function by Promoting AMP-Mediated Protein Kinase in Diabetic Mice. Cell reports, 22(7), 1760-1773.
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6

Continuous Metabolic Monitoring in Mice

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Metabolic measurements were obtained continuously using TSE metabolic chambers (TSE Labmaster System, Germany) in an open-circuit indirect calorimetry system. Studies were performed from days 4 to 6 after implanting osmotic pumps. Data were normalized to lean body mass as determined using a Bruker MQ10 NMR analyzer.
Sharma A.X., Quittner-Strom E.B., Lee Y., Johnson J.A., Martin S.A., Yu X., Li J., Lu J., Cai Z., Chen S., Wang M.Y., Zhang Y., Pearson M.J., Dorn A.C., McDonald J.G., Gordillo R., Yan H., Thai D., Wang Z.V., Unger R.H, & Holland W.L. (2018). Glucagon Receptor Antagonism Improves Glucose Metabolism and Cardiac Function by Promoting AMP-Mediated Protein Kinase in Diabetic Mice. Cell reports, 22(7), 1760-1773.
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