Magnetom prisma fit 3 tesla mri scanner

MRI data from diffuse glioma patients were acquired at the Wolfson Brain Imaging Centre (University of Cambridge) using a Siemens Magnetom Prisma-fit 3 Tesla MRI scanner and 16-channel receive-only head coil (Siemens AG, Erlangen, Germany). A T1-weighted MPRAGE sequence was acquired using the following parameters: repetition time (TR) = 2300 ms, echo time (TE) = 2.98 ms, flip angle (FA) = 9°, 1 mm³ resolution, field of view (FOV) = 256 × 240 mm², 192 contiguous slices and acquisition time of 9 min and 14 s. During the same scanning session, we acquired resting-state (eyes closed) fMRI with a BOLD-sensitive sequence: TR = 1060 ms, TE= 30 ms, acceleration factor = 4, FA = 74°, 2 mm³ resolution, FOV = 192 × 192 mm² and acquisition time of 9 min and 10 s. fMRI pre-processing was based on independent component analysis (ICA) performed with FSL MELODIC. Noise components were identified and removed using ICA-FIX [30 (link)] with training specific to this dataset [31 (link)]. Additional processing steps included slice timing correction, bias field correction, rigid body motion correction, normalisation by a single scaling factor and smoothing to 5 mm fixed-width half-maximum. We focused on the physiologically relevant frequency range by using wavelet filtering that retained the BOLD oscillations in the frequency range 0.03–0.12 Hz (wavelet scales 3 and 4) [32 (link)].

After a mock scanner training session, magnetic resonance imaging (MRI) was performed using a Siemens MAGNETOM Prisma^fit 3 Tesla MRI scanner (Siemens Medical Systems) with a 20-channel phased array coil. A high-resolution magnetic resonance imaging scan was acquired using a T1-weighted three-dimensional magnetization prepared rapid gradient echo (MP-RAGE) sequence with the parameters: 256 × 256 × 176-matrix size with 1 × 1 × 1-mm³ resolution; inversion time = 900 ms; repetition time (TR) = 1950 ms; echo time (TE) = 2.26 ms; flip angle = 90°; Total scan duration was 4 min and 14 s. A diffusion weighted image was acquired using a dual spin echo, single shot, pulsed gradient, echo planar imaging sequence in 64 diffusion sensitized gradient directions with the following parameters: TR = 8100 ms; TE = 69 ms; flip angle = 90°; 70 axial slices; 2 mm × 2 mm × 2 mm voxel size; FOV = 256 mm; b value = 1000 s/mm²; Total scan duration was 9 min and 29 s.

After a mock scanner training session, magnetic resonance imaging was performed using a Siemens MAGNETOM Prisma^fit 3‐Tesla MRI scanner (Siemens Medical Systems) with a 20‐channel phased array coil. The MRI session started with a localizer scan. A high‐resolution MRI scan was acquired using a T1‐weighted three‐dimensional magnetization prepared rapid gradient echo (MP‐RAGE) sequence with the parameters: 256 × 256 × 176‐matrix size with 1 × 1 × 1‐mm³ resolution; inversion time = 900 ms; repetition time (TR) = 1,950 ms; echo time (TE) = 2.26 ms; flip angle = 90°; and total scan duration was 4 min and 14 s.