Dipyridamole

Manufactured by Fujifilm

Sourced in Japan

Dipyridamole is a laboratory equipment product used for various analytical and research applications. It functions as a chemical reagent that can be used in various analytical techniques. The core function of Dipyridamole is to serve as a tool for researchers and scientists in their laboratory work.

Automatically generated - may contain errors

Lab products found in correlation

3 protocols using dipyridamole

Prostanoid and Nucleotide Quantification

Check if the same lab product or an alternative is used in the 5 most similar protocols

All prostanoids (PGE₃, PGF_3α, TXB₃, PGE₂, PGF_2α, and TXB₂), deuterated prostanoids (PGE₂-d4, PGF_2α-d4, and TXB₂-d4), and EPA were purchased from Cayman Chemical Co. (Ann Arbor, MI). Calcium ionophore A23187 and indomethacin were purchased from Sigma Aldrich (St. Louis, MO). Adenosine 5′-triphosphate (ATP) disodium salt hydrate, 5′-adenylic acid (AMP), and sodium creatine phosphate hydrate were purchased from Tokyo Chemical Industry Co., Ltd. (Tokyo, Japan). Creatine kinase was purchased from Roche Applied Science (Tokyo, Japan). Dipyridamole, probenecid, quercetin, methotrexate, and folic acid were purchased from Wako Pure Chemical Industries (Osaka, Japan). MK571, celecoxib, candesartan, estradiol 17β-glucronide (E₂17βG), adenosine 3′, 5′-cyclic monophosphate (cAMP), and guanosine 3′, 5′-cyclic monophosphate (cGMP) were purchased from Sigma Aldrich (St. Louis, MO). All other chemicals were of the highest purity available.

Tanaka N., Yamaguchi H, & Mano N. (2014). Transport of Eicosapentaenoic Acid-Derived PGE3, PGF3α, and TXB3 by ABCC4. PLoS ONE, 9(10), e109270.

+ Open protocol

+ Expand

Solubility Measurement of Pharmaceutical Compounds

Check if the same lab product or an alternative is used in the 5 most similar protocols

Albendazole was purchased from Tokyo Chemical Industry Co., Ltd (Tokyo, Japan). Griseofulvin, dipyridamole, and glibenclamide were purchased from FUJIFILM Wako Pure Chemical Corporation (Osaka, Japan). An identical batch was used by all companies.
The Japanese Pharmacopeia (JP) 2^nd fluid for dissolution testing (12.5 mM KH₂PO₄ and 12.5 mM Na₂HPO₄, pH 6.8, buffer capacity 10 mM/ ΔpH) was used for the solubility measurement.

Ono A., Matsumura N., Kimoto T., Akiyama Y., Funaki S., Tamura N., Hayashi S., Kojima Y., Fushimi M., Sudaki H., Aihara R., Haruna Y., Jiko M., Iwasaki M., Fujita T, & Sugano K. (2019). Harmonizing solubility measurement to lower inter-laboratory variance – progress of consortium of biopharmaceutical tools (CoBiTo) in Japan. ADMET & DMPK, 7(3), 183-195.

+ Open protocol

+ Expand

Screening of BCS Class II APIs

Check if the same lab product or an alternative is used in the 5 most similar protocols

Materials Three highly water-insoluble BCS class II classified compounds, namely, nifedipine, which is a weak base (Daito pharmaceutical, Japan), Fenofibrate, a neutral compound (Moehs coprima, Spain), Indomethacin, which is an acid-base compound (Sogo pharmaceutical, Japan) were used as model API for screening studies. The physicochemical properties and morphology of the model APIs are indicated in Table 1 and Fig. 1, respectively. Other APIs were also used as model compound classified in BCS class II. Cilostazol was purchased from Daito Pharmaceutical (Japan). Phenytoin, bezafibrate, itraconazole, piroxicam, dipyridamole, and ketoprofen were purchased from Wako (Japan). The dispersing agents and wetting agents used in this study are listed in Tables 2,3, respectively. These tables were summarized from each vendor's technical catalogs. Dispersing agents and wetting agents were selected from common polymer and surfactant in the pharmaceutical industry. Other reagents for quality testing were purchased from Wako (Japan).

Fujii H, & Watano S. (2019). Development of Universal Formulation with Superior Re-dispersion Using Nanocrystal Approach with Simultaneous Identification of API Physicochemical Properties. Chemical & pharmaceutical bulletin, 67(10).

+ Open protocol

+ Expand

About PubCompare

Our mission is to provide scientists with the largest repository of trustworthy protocols and intelligent analytical tools, thereby offering them extensive information to design robust protocols aimed at minimizing the risk of failures.

We believe that the most crucial aspect is to grant scientists access to a wide range of reliable sources and new useful tools that surpass human capabilities.

However, we trust in allowing scientists to determine how to construct their own protocols based on this information, as they are the experts in their field.

Ready to get started?

Revolutionizing how scientists
search and build protocols!