Rs 3 5 dihydroxyphenylglycine dhpg
(RS)-3,5-dihydroxyphenylglycine (DHPG) is a synthetic compound commonly used as a research tool in neuroscience studies. It is a selective agonist for the metabotropic glutamate receptor subtype 5 (mGluR5). DHPG can be utilized to investigate the role of mGluR5 in various neurological processes and pathways.
Lab products found in correlation
7 protocols using rs 3 5 dihydroxyphenylglycine dhpg
Immunoblotting and Immunocytochemistry Protocols
Immunoblotting of Glutamate Receptors
Inhibition of Neuronal Synaptic Signaling
Selective mGlu5 Receptor PAM Protocol
GABAzine and kynurenic acid were obtained from Hello Bio (Bristol, UK).
Pharmacological Modulation of Synaptic Plasticity
The drugs were made up as stock solutions in either double-distilled water (D-APV, NMDA, anisomycin and DHPG) or 99% v/v. DMSO (Cycloheximide) at 10-1000-fold their final concentration and stored at -20°C. DMSO at final concentration of 0.01–0.1% was added to the solution of the control group as vehicle to balance any slight effect it might have on LTD. These stocks were diluted in aCSF to achieve their desired final concentrations and were applied by switching the perfusion from control aCSF to drug-containing aCSF.
Neuromodulation drug administration protocols
Arachidonic Acid Metabolite Assay
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